Papa, S orcid.org/0000-0002-8369-6538 and Bubici, C (2016) Linking apoptosis to cancer metabolism: Another missing piece of JuNK. Molecular & Cellular Oncology, 3 (2). e1103398. ISSN 2372-3556
Abstract
Cancer cells become dependent on aerobic glycolysis to sustain rapid proliferation and escape apoptosis. How this metabolic change, also known as the Warburg effect, is linked to apoptosis remains largely unknown. Our new data place c-Jun N-terminal kinase in the center of a hub regulating apoptosis and cancer metabolism.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2016 The Author(s). Published with license by Taylor & Francis Group, LLC© Salvatore Papa and Concetta Bubici. This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License http://creativecommons.org/licenses/by-nc/3.0/, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted. |
Keywords: | Aerobic glycolysis, cancer, JNK, PARP14, PKM2 |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > Institute of Molecular Medicine (LIMM) (Leeds) > Section of Experimental Haematology (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 14 Jul 2016 14:36 |
Last Modified: | 14 Jul 2016 14:36 |
Published Version: | http://dx.doi.org/10.1080/23723556.2015.1103398 |
Status: | Published |
Publisher: | Taylor & Francis |
Identification Number: | 10.1080/23723556.2015.1103398 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:100527 |