Cellular proteostasis: degradation of misfolded proteins by lysosomes

Jackson, MP and Hewitt, EW orcid.org/0000-0002-6238-6303 (2016) Cellular proteostasis: degradation of misfolded proteins by lysosomes. Essays in Biochemistry, 60 (2). pp. 173-180. ISSN 0071-1365



Copyright, Publisher and Additional Information: © 2016 The Author(s). This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution Licence 4.0 (CC BY).
Keywords: amyloid; α-synuclein; autophagy; β2-microglobulin; chaperone mediated autophagy; immunoglobulin light chain; lysosome; macroautophagy; mTOR; Parkinson’s; protein aggregation; protein misfolding; proteostasis; rapamycin; TFEB
  • Accepted: 29 April 2016
  • Published: 15 October 2016
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Molecular and Cellular Biology (Leeds)
Funding Information:
FunderGrant number
Wellcome Trust092896/Z/10/Z
Depositing User: Symplectic Publications
Date Deposited: 10 May 2016 10:51
Last Modified: 23 Jun 2023 22:05
Published Version: https://doi.org/10.1042/EBC20160005
Status: Published
Publisher: Portland Press
Identification Number: https://doi.org/10.1042/EBC20160005