Imatinib Mesylate Exerts Anti-Proliferative Effects on Osteosarcoma Cells and Inhibits the Tumour Growth in Immunocompetent Murine Models

Gobin, B., Moriceau, G., Ory, B. et al. (5 more authors) (2014) Imatinib Mesylate Exerts Anti-Proliferative Effects on Osteosarcoma Cells and Inhibits the Tumour Growth in Immunocompetent Murine Models. PLoS ONE, 9 (3). e90795. ISSN 1932-6203

Abstract

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Authors/Creators:
Copyright, Publisher and Additional Information: Copyright: © 2014 Gobin et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. http://creativecommons.org/licenses/by/4.0/
Keywords: Animals; Antineoplastic Agents; Benzamides; Caspases; Cell Cycle Checkpoints; Cell Death; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Disease Progression; Humans; Imatinib Mesylate; Immunocompetence; Male; Mice; Mice, Inbred C57BL; Mitosis; Osteosarcoma; Piperazines; Proto-Oncogene Proteins c-akt; Pyrimidines; Rats; Receptor, Platelet-Derived Growth Factor alpha; Signal Transduction; TOR Serine-Threonine Kinases
Dates:
  • Published: 5 March 2014
  • Accepted: 4 February 2014
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine (Sheffield) > Division of Genomic Medicine (Sheffield) > Department of Oncology (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 13 Apr 2016 09:26
Last Modified: 13 Apr 2016 09:26
Published Version: http://dx.doi.org/10.1371/journal.pone.0090795
Status: Published
Publisher: Public Library of Science
Refereed: Yes
Identification Number: https://doi.org/10.1371/journal.pone.0090795
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