The design and evaluation of interfaces for navigating gigapixel images in digital pathology

This paper describes the design and evaluation of two generations of an interface for navigating datasets of gigapixel images that pathologists use to diagnose cancer. The interface design is innovative because

users panned with an overview:detail view scale difference that was up to 57 times larger than established guidelines, and 1 million pixel ‘thumbnail’ overviews that leveraged the real-estate of high resolution

workstation displays. The research involved experts performing real work (pathologists diagnosing cancer), using datasets that were up to 3150 times larger than those used in previous studies that involved

navigating images. The evaluation provides evidence about the effectiveness of the interfaces, and characterizes how experts navigate gigapixel images when performing real work. Similar interfaces could

be adopted in applications that use other types of high-resolution images (e.g., remote sensing or highthroughput microscopy).