Neuronal DNA damage response-associated dysregulation of signalling pathways and cholesterol metabolism at the earliest stages of Alzheimer-type pathology.

Simpson, J.E., Ince, P.G., Minett, T. et al. (9 more authors) (2015) Neuronal DNA damage response-associated dysregulation of signalling pathways and cholesterol metabolism at the earliest stages of Alzheimer-type pathology. Neuropathology and Applied Neurobiology. ISSN 0305-1846

Abstract

Metadata

Authors/Creators:
  • Simpson, J.E.
  • Ince, P.G.
  • Minett, T.
  • Matthews, F.E.
  • Heath, P.R.
  • Shaw, P.J.
  • Goodall, E.
  • Garwood, C.J.
  • Ratcliffe, L.E.
  • Brayne, C.
  • Rattray, M.
  • Wharton, S.B.
Copyright, Publisher and Additional Information: © 2015. The Author(s). This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Keywords: DNA damage response; GSK3β; Wnt signalling; ageing brain; cholesterol biosynthesis; insulin signalling; microarray; neurones
Dates:
  • Published: 7 July 2015
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine (Sheffield) > Department of Neuroscience (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 14 Jul 2015 12:28
Last Modified: 14 Jul 2015 12:28
Published Version: http://dx.doi.org/10.1111/nan.12252
Status: Published
Publisher: Blackwell Publishing
Refereed: Yes
Identification Number: https://doi.org/10.1111/nan.12252
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