Amyotrophic lateral sclerosis-associated mutant VAPBP56S perturbs calcium homeostasis to disrupt axonal transport of mitochondria.

Mórotz, G.M., De Vos, K.J., Vagnoni, A. et al. (3 more authors) (2012) Amyotrophic lateral sclerosis-associated mutant VAPBP56S perturbs calcium homeostasis to disrupt axonal transport of mitochondria. Human Molecular Genetics, 21 (9). 1979 - 1988. ISSN 0964-6906

Abstract

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Authors/Creators:
  • Mórotz, G.M.
  • De Vos, K.J.
  • Vagnoni, A.
  • Ackerley, S.
  • Shaw, C.E.
  • Miller, C.C.
Copyright, Publisher and Additional Information: © The Author 2012. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial Licence (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use the material for commercial purposes.
Keywords: Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Animals; Axonal Transport; Base Sequence; Calcium; HEK293 Cells; Homeostasis; Humans; Kinesin; Mitochondria; Mitochondrial Proteins; Movement; Mutagenesis, Site-Directed; Mutant Proteins; Neurons; Plasmids; Rats; Recombinant Proteins; Time-Lapse Imaging; Transfection; Tubulin; Vesicular Transport Proteins; rho GTP-Binding Proteins
Dates:
  • Published: 1 May 2012
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine (Sheffield) > Department of Neuroscience (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 22 Jun 2015 10:07
Last Modified: 22 Jun 2015 10:07
Published Version: http://dx.doi.org/10.1093/hmg/dds011
Status: Published
Publisher: Oxford University Press
Refereed: Yes
Identification Number: https://doi.org/10.1093/hmg/dds011
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