An investigation of the impact of futility analysis in publicly funded trials

Sully, B.G.O., Julious, S.A. and Nicholl, J. (2014) An investigation of the impact of futility analysis in publicly funded trials. Trials, 15. ARTN 61. ISSN 1745-6215



  • Sully, B.G.O.
  • Julious, S.A.
  • Nicholl, J.
Copyright, Publisher and Additional Information: © Sully et al.; licensee BioMed Central Ltd. 2014. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.
Keywords: Adaptive designs; Futility; Recruitment; Efficiency; Health technology assessment; Medical research council
  • Accepted: 23 January 2014
  • Published: 17 February 2014
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Health and Related Research (Sheffield) > ScHARR - Sheffield Centre for Health and Related Research
Depositing User: Symplectic Sheffield
Date Deposited: 29 Jul 2016 12:57
Last Modified: 29 Mar 2018 13:03
Published Version:
Status: Published
Publisher: BioMed Central
Refereed: Yes
Identification Number:
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