Giovannoni, G., Ford, H.L., Schmierer, K. et al. (12 more authors) (2024) MS care: integrating advanced therapies and holistic management. Frontiers in Neurology, 14. ARTN 1286122. ISSN 1664-2295
Abstract
Lifestyle and environmental factors are key determinants in disease causality and progression in neurological conditions, including multiple sclerosis (MS). Lack of exercise, poor diet, tobacco smoking, excessive alcohol intake, social determinants of health, concomitant medications, poor sleep and comorbidities can exacerbate MS pathological processes by impacting brain health and depleting neurological reserves, resulting in more rapid disease worsening. In addition to using disease-modifying therapies to alter the disease course, therapeutic strategies in MS should aim to preserve as much neurological reserve as possible by promoting the adoption of a “brain-healthy” and “metabolically-healthy” lifestyle. Here, we recommend self-regulated lifestyle modifications that have the potential to improve brain health, directly impact on disease progression and improve outcomes in people with MS. We emphasise the importance of self-management and adopting a multidisciplinary, collaborative and person-centred approach to care that encompasses the healthcare team, family members and community support groups.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2023 Giovannoni, Ford, Schmierer, Middleton, Stennett, Pomeroy, Fisniku, Scalfari, Bannon, Stross, Hughes, Williams, Josephs, Peel and Straukiene. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
Keywords: | multiple sclerosis; brain health; lifestyle; disease progression; outcomes; holistic care; recommendations |
Dates: |
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Institution: | The University of Leeds |
Depositing User: | Symplectic Publications |
Date Deposited: | 04 Apr 2024 10:44 |
Last Modified: | 04 Apr 2024 10:44 |
Published Version: | http://dx.doi.org/10.3389/fneur.2023.1286122 |
Status: | Published online |
Publisher: | Frontiers Media SA |
Identification Number: | https://doi.org/10.3389/fneur.2023.1286122 |
Related URLs: |