ISSCR standards for the use of human stem cells in basic research

Abstract

The laboratory culture of human stem cells seeks to capture a cellular state as an in vitro surrogate of a biological system. For the results and outputs from this research to be accurate, meaningful, and durable, standards that ensure reproducibility and reliability of the data should be applied. Although such standards have been previously proposed for repositories and distribution centers, no widely accepted best practices exist for laboratory research with human pluripotent and tissue stem cells. To fill that void, the International Society for Stem Cell Research has developed a set of recommendations, including reporting criteria, for scientists in basic research laboratories. These criteria are designed to be technically and financially feasible and, when implemented, enhance the reproducibility and rigor of stem cell research.

Metadata

Item Type:

Article

Authors/Creators:

Ludwig, T.E.
Andrews, P.W. https://orcid.org/0000-0001-7215-4410
Barbaric, I.
Benvenisty, N.
Bhattacharyya, A.
Crook, J.M.
Daheron, L.M.
Draper, J.S.
Healy, L.E.
Huch, M.
Inamdar, M.S.
Jensen, K.B.
Kurtz, A.
Lancaster, M.A.
Liberali, P.
Lutolf, M.P.
Mummery, C.L.
Pera, M.F.
Sato, Y.
Shimasaki, N.
Smith, A.G.
Song, J.
Spits, C.
Stacey, G.
Wells, C.A.
Zhao, T.
Mosher, J.T.

© 2023 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives licence (https://creativecommons.org/licenses/by-nc-nd/4.0/)

Keywords:

hESCS; hIPSCs; human; model systems; organoids; tissue stem cells; Humans; Reproducibility of Results; Stem Cell Research

Dates: