Clinical effectiveness and cost-effectiveness of supported mindfulness-based cognitive therapy self-help compared with supported cognitive behavioral therapy self-help for adults experiencing depression

Abstract

Question Is practitioner-supported mindfulness-based cognitive therapy self-help (MBCT-SH) clinically effective and cost-effective compared with practitioner-supported cognitive behavioral therapy self-help (CBT-SH) for adults experiencing mild to moderate depression?

Findings In this randomized clinical trial of 410 participants with mild to moderate depression, practitioner-supported MBCT-SH led to significantly greater reductions in depressive symptom severity at 16 weeks postrandomization compared with practitioner-supported CBT-SH. The probability of MBCT-SH being cost-effective compared with CBT-SH exceeded 95%.

Meaning Practitioner-supported MBCT-SH for mild to moderate depression was clinically effective and cost-effective compared with currently recommended practitioner-supported CBT-SH and should be made routinely available to adults experiencing mild to moderate depression.

Metadata

Authors/Creators:

Strauss, C.
Bibby-Jones, A.-M.
Jones, F.
Byford, S.
Heslin, M.
Parry, G.
Barkham, M. https://orcid.org/0000-0003-1687-6376
Lea, L.
Crane, R.
de Visser, R.
Arbon, A.
Rosten, C.
Cavanagh, K.

© 2023 Strauss C et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Dates:

Accepted: 26 January 2023
Published (online): 22 March 2023

Institution:

The University of Sheffield

Academic Units:

The University of Sheffield > Faculty of Science (Sheffield) > Department of Psychology (Sheffield)

Funding Information:

Funder	Grant number
DEPARTMENT OF HEALTH AND SOCIAL CARE	PB-PG-0815-20056

Depositing User:

Symplectic Sheffield

Date Deposited:

24 Mar 2023 09:54

Last Modified:

24 Mar 2023 09:54

Status:

Published online

Publisher:

American Medical Association (AMA)

Refereed:

Yes

Identification Number:

https://doi.org/10.1001/jamapsychiatry.2023.0222

Related URLs:

PubMed URL

CORE (COnnecting REpositories)

Clinical effectiveness and cost-effectiveness of supported mindfulness-based cognitive therapy self-help compared with supported cognitive behavioral therapy self-help for adults experiencing depression

Abstract

Metadata

Download

Published Version

Export

Statistics