Kpeglo, D, Knowles, M orcid.org/0000-0002-9363-8657, Haddrick, M et al. (2 more authors) (2021) MODELLING THE BIOPHYSICS OF PANCREATIC DUCTAL ADENOCARCINOMA ON-CHIP FOR EFFECTIVE THERAPEUTIC ASSESSMENT. In: MicroTAS 2021, 10-14 Oct 2021, Florida, USA.
Abstract
This paper presents a microfluidic device for modelling the biophysics of pancreatic ductal adenocarcinoma (PDAC). The biophysics of PDAC hampers the delivery and uptake of chemotherapeutic drugs to the PDAC cancer cells. Understanding and modelling the biophysical nature of PDAC, its fibrotic stroma, and mechanical stiffness is key to effectively targeting PDAC cells with therapeutics.
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Institution: | The University of Leeds | ||||||
Academic Units: | The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Physics and Astronomy (Leeds) > Molecular & Nanoscale Physics | ||||||
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Depositing User: | Symplectic Publications | ||||||
Date Deposited: | 24 Feb 2023 14:58 | ||||||
Last Modified: | 24 Feb 2023 14:58 | ||||||
Status: | Published | ||||||
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