Targeting the adrenomedullin-2 receptor for the discovery and development of novel anti-cancer agents

Jailani, A.B.A. orcid.org/0000-0001-9837-6062, Bigos, K.J.A., Avgoustou, P. orcid.org/0000-0002-1642-1083 et al. (4 more authors) (2022) Targeting the adrenomedullin-2 receptor for the discovery and development of novel anti-cancer agents. Expert Opinion on Drug Discovery, 17 (8). pp. 839-848. ISSN 1746-0441

Abstract

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Authors/Creators:
Copyright, Publisher and Additional Information: © 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Keywords: Adrenomedullin; angiogenesis; antagonists; cancer; calcitonin receptor-like receptor; receptor activity-modifying protein; therapeutic target; G protein-coupled receptor; hypoxia; metastasis
Dates:
  • Accepted: 13 June 2022
  • Published (online): 22 June 2022
  • Published: 3 August 2022
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Science (Sheffield) > Department of Chemistry (Sheffield)
Funding Information:
FunderGrant number
Prostate Cancer UKPA12-12
The Wellcome Trust104046/Z/14/1; 205291/Z/16/Z
Depositing User: Symplectic Sheffield
Date Deposited: 08 Sep 2022 11:05
Last Modified: 08 Sep 2022 11:05
Status: Published
Publisher: Taylor & Francis
Refereed: Yes
Identification Number: https://doi.org/10.1080/17460441.2022.2090541
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