Defective repair of topoisomerase I induced chromosomal damage in Huntington’s disease

Palminha, N.M., Dos Santos Souza, C. orcid.org/0000-0001-5314-6263, Griffin, J. orcid.org/0000-0003-3969-7637 et al. (3 more authors) (2022) Defective repair of topoisomerase I induced chromosomal damage in Huntington’s disease. Cellular and Molecular Life Sciences, 79 (3). 160. ISSN 1420-682X

Abstract

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Copyright, Publisher and Additional Information: © 2022 The Author(s). This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
Keywords: Chromatin ubiquitination; DNA repair; Huntington’s disease; RNF168; TOP1cc; p62/SQSTM1
Dates:
  • Accepted: 8 February 2022
  • Published (online): 28 February 2022
  • Published: March 2022
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > Department of Neuroscience (Sheffield)
Funding Information:
FunderGrant number
The Wellcome Trust103844/Z/14/Z
Depositing User: Symplectic Sheffield
Date Deposited: 07 Mar 2022 08:36
Last Modified: 07 Mar 2022 08:36
Status: Published
Publisher: Springer Nature
Refereed: Yes
Identification Number: https://doi.org/10.1007/s00018-022-04204-6
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