Diagnosis and management of secondary HLH/MAS following HSCT and CAR-T cell therapy in adults; a review of the literature and a survey of practice within EBMT centres on behalf of the Autoimmune Diseases Working Party (ADWP) and Transplant Complications Working Party (TCWP)

Sandler, R.D. orcid.org/0000-0002-6933-9921, Tattersall, R.S. orcid.org/0000-0002-1087-6546, Schoemans, H. et al. (14 more authors) (2020) Diagnosis and management of secondary HLH/MAS following HSCT and CAR-T cell therapy in adults; a review of the literature and a survey of practice within EBMT centres on behalf of the Autoimmune Diseases Working Party (ADWP) and Transplant Complications Working Party (TCWP). Frontiers in Immunology, 11. 524.

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Authors/Creators:
Copyright, Publisher and Additional Information: © 2020 The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Keywords: CAR-T cell; GVHD; HLH hemophagocytic lymphohistiocytosis; HSCT; biomarkers; ferritin; macrophage activation syndrome (MAS); Adult; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunotherapy, Adoptive; Lymphohistiocytosis, Hemophagocytic; Macrophage Activation Syndrome; Male; Middle Aged; Receptors, Chimeric Antigen; Surveys and Questionnaires
Dates:
  • Accepted: 9 March 2020
  • Published (online): 31 March 2020
  • Published: 31 March 2020
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Sheffield Teaching Hospitals
Depositing User: Symplectic Sheffield
Date Deposited: 27 Jul 2021 10:33
Last Modified: 27 Jul 2021 11:12
Status: Published
Publisher: Frontiers Media SA
Refereed: Yes
Identification Number: https://doi.org/10.3389/fimmu.2020.00524
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