Distinct concentration-dependent molecular pathways regulate bone cell responses to cobalt and chromium exposure from joint replacement prostheses

Shah, K.M. orcid.org/0000-0001-9909-6409, Dunning, M.J. orcid.org/0000-0002-8853-9435, Gartland, A. orcid.org/0000-0002-3712-2437 et al. (1 more author) (2021) Distinct concentration-dependent molecular pathways regulate bone cell responses to cobalt and chromium exposure from joint replacement prostheses. International Journal of Molecular Sciences, 22 (10). 5225. ISSN 1661-6596

Abstract

Metadata

Authors/Creators:
Copyright, Publisher and Additional Information: © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Keywords: hip replacement; osteoblasts; osteoclasts; cobalt; chromium; gene expression; microarray; prosthesis surface
Dates:
  • Accepted: 8 May 2021
  • Published (online): 14 May 2021
  • Published: 14 May 2021
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Sheffield Teaching Hospitals
Funding Information:
FunderGrant number
ORTHOPAEDIC RESEARCH UKnan
Depositing User: Symplectic Sheffield
Date Deposited: 18 Jun 2021 15:12
Last Modified: 18 Jun 2021 15:12
Status: Published
Publisher: MDPI AG
Refereed: Yes
Identification Number: https://doi.org/10.3390/ijms22105225

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