Small molecule inhibitor of OGG1 blocks oxidative DNA damage repair at telomeres and potentiates methotrexate anticancer effects

Baquero, J.M., Benítez-Buelga, C., Rajagopal, V. et al. (13 more authors) (2021) Small molecule inhibitor of OGG1 blocks oxidative DNA damage repair at telomeres and potentiates methotrexate anticancer effects. Scientific Reports, 11 (1). 3490.

Abstract

Metadata

Authors/Creators:
  • Baquero, J.M.
  • Benítez-Buelga, C.
  • Rajagopal, V.
  • Zhenjun, Z.
  • Torres-Ruiz, R.
  • Müller, S.
  • Hanna, B.M.F.
  • Loseva, O.
  • Wallner, O.
  • Michel, M.
  • Rodríguez-Perales, S.
  • Gad, H.
  • Visnes, T.
  • Helleday, T. ORCID logo https://orcid.org/0000-0002-7384-092X
  • Benítez, J.
  • Osorio, A.
Copyright, Publisher and Additional Information: © 2021 The Author(s). This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
Dates:
  • Accepted: 18 January 2021
  • Published (online): 10 February 2021
  • Published: 10 February 2021
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 25 Mar 2021 11:07
Last Modified: 25 Mar 2021 11:55
Status: Published
Publisher: Springer Nature
Refereed: Yes
Identification Number: https://doi.org/10.1038/s41598-021-82917-7
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