Altered network properties in C9ORF72 repeat expansion cortical neurons are due to synaptic dysfunction

Perkins, E.M., Burr, K., Banerjee, P. et al. (11 more authors) (2021) Altered network properties in C9ORF72 repeat expansion cortical neurons are due to synaptic dysfunction. Molecular Neurodegeneration, 16 (1). 13.

Abstract

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Authors/Creators:
  • Perkins, E.M.
  • Burr, K.
  • Banerjee, P.
  • Mehta, A.R.
  • Dando, O.
  • Selvaraj, B.T.
  • Suminaite, D.
  • Nanda, J.
  • Henstridge, C.M.
  • Gillingwater, T.H.
  • Hardingham, G.E.
  • Wyllie, D.J.A.
  • Chandran, S.
  • Livesey, M.R. ORCID logo https://orcid.org/0000-0002-3441-7977
Copyright, Publisher and Additional Information: © 2021 The Author(s). This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
Keywords: ALS; C9ORF72; Cortical; Electrophysiology; FTD; Hyperexcitability; Network; Neuron; Repeat expansion; Synaptic
Dates:
  • Accepted: 14 February 2021
  • Published (online): 4 March 2021
  • Published: 4 March 2021
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > Department of Neuroscience (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 23 Mar 2021 07:55
Last Modified: 23 Mar 2021 08:47
Status: Published
Publisher: BioMed Central
Refereed: Yes
Identification Number: https://doi.org/10.1186/s13024-021-00433-8
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