Design of synthetic promoters for controlled expression of therapeutic genes in retinal pigment epithelial cells

Johari, Y.B., Mercer, A.C., Liu, Y. et al. (2 more authors) (2021) Design of synthetic promoters for controlled expression of therapeutic genes in retinal pigment epithelial cells. Biotechnology and Bioengineering. ISSN 0006-3592

Abstract

Metadata

Authors/Creators:
  • Johari, Y.B.
  • Mercer, A.C.
  • Liu, Y.
  • Brown, A.J.
  • James, D.C.
Copyright, Publisher and Additional Information: © 2021 The Authors. Biotechnology and Bioengineering Published by Wiley Periodicals LLC. This is an open access article under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/4.0/) which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Keywords: cell‐specific expression; gene therapy; RPE cells; synthetic biology; synthetic promoter; transcriptomics
Dates:
  • Accepted: 11 February 2021
  • Published (online): 3 March 2021
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Engineering (Sheffield) > Department of Chemical and Biological Engineering (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 15 Mar 2021 13:43
Last Modified: 15 Mar 2021 13:43
Status: Published online
Publisher: Wiley
Refereed: Yes
Identification Number: https://doi.org/10.1002/bit.27713
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