Analysis of mechanotransduction dynamics during combined mechanical stimulation and modulation of the extracellular-regulated kinase cascade uncovers hidden information within the signalling noise

Ascolani, G., Skerry, T.M. orcid.org/0000-0003-1319-5575, Lacroix, D. orcid.org/0000-0002-5482-6006 et al. (2 more authors) (2021) Analysis of mechanotransduction dynamics during combined mechanical stimulation and modulation of the extracellular-regulated kinase cascade uncovers hidden information within the signalling noise. Interface Focus, 11 (1). 20190136. ISSN 2042-8901

Abstract

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Authors/Creators:
Copyright, Publisher and Additional Information: © 2020 The Author(s). This is an author-produced version of a paper subsequently published in Interface Focus. Uploaded in accordance with the publisher's self-archiving policy.
Keywords: osteoporosis; dual biomechanical signalling; mechanotransduction; multiscale model; agent-based modelling; subordination theory
Dates:
  • Accepted: 23 September 2020
  • Published (online): 11 December 2020
  • Published: 6 February 2021
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Engineering (Sheffield) > Department of Mechanical Engineering (Sheffield)
Funding Information:
FunderGrant number
Engineering and Physical Sciences Research CouncilEP/K03877X/1
Depositing User: Symplectic Sheffield
Date Deposited: 08 Feb 2021 11:44
Last Modified: 08 Feb 2021 12:25
Status: Published
Publisher: The Royal Society
Refereed: Yes
Identification Number: https://doi.org/10.1098/rsfs.2019.0136
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