Sphingomyelinase Disables Inactivation in Endogenous PIEZO1 Channels

Shi, J, Hyman, AJ, De Vecchis, D et al. (8 more authors) (2020) Sphingomyelinase Disables Inactivation in Endogenous PIEZO1 Channels. Cell Reports, 33 (1). 108225. ISSN 2211-1247

Abstract

Metadata

Authors/Creators:
Copyright, Publisher and Additional Information: © 2020 The Authors. This is an open access article under the terms of the Creative Commons Attribution License (CC-BY) (https://creativecommons.org/licenses/by/4.0/)
Keywords: PIEZO1; inactivation; endothelium; sphingomyelinase; SMPD3; ceramide; sphingomyelin; mechanically activated channel; molecular dynamics; simualtions
Dates:
  • Accepted: 11 September 2020
  • Published (online): 6 October 2020
  • Published: 6 October 2020
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM) > Discovery & Translational Science Dept (Leeds)
Funding Information:
FunderGrant number
British Heart FoundationFS/17/2/32559
British Heart FoundationRG/17/11/33042
MRC (Medical Research Council)MR/R01745X/1
Wellcome Trust110044/Z/15/Z
Depositing User: Symplectic Publications
Date Deposited: 16 Sep 2020 15:08
Last Modified: 02 Dec 2020 11:40
Status: Published
Publisher: Cell Press
Identification Number: https://doi.org/10.1016/j.celrep.2020.108225

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