Design, synthesis, and biological evaluation of aryl piperazines with potential as antidiabetic agents via the stimulation of glucose uptake and inhibition of NADH:ubiquinone oxidoreductase

Devine, R, Kelada, M, Leonard, S et al. (7 more authors) (2020) Design, synthesis, and biological evaluation of aryl piperazines with potential as antidiabetic agents via the stimulation of glucose uptake and inhibition of NADH:ubiquinone oxidoreductase. European Journal of Medicinal Chemistry, 202. 112416. ISSN 0223-5234

Abstract

Metadata

Authors/Creators:
  • Devine, R
  • Kelada, M
  • Leonard, S
  • Martin, DSD
  • Walsh, JMD
  • Breen, CJ
  • Driver, RB
  • Kinsella, GK
  • Findlay, JBC
  • Stephens, JC
Keywords: Diabetes; Glucose uptake; Complex 1; Piperazine; Pharmacokinetics; Structure activity relationship
Dates:
  • Published: 15 September 2020
  • Accepted: 29 April 2020
  • Published (online): 27 June 2020
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Biomedical Sciences (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 13 Aug 2020 13:35
Last Modified: 13 Aug 2020 13:35
Status: Published
Publisher: Elsevier
Identification Number: https://doi.org/10.1016/j.ejmech.2020.112416

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