MYCN expression induces replication stress and sensitivity to PARP inhibition in neuroblastoma

King, D., Li, X.D., Almeida, G.S. et al. (13 more authors) (2020) MYCN expression induces replication stress and sensitivity to PARP inhibition in neuroblastoma. Oncotarget, 11 (23). pp. 2141-2159.

Abstract

Metadata

Authors/Creators:
  • King, D.
  • Li, X.D.
  • Almeida, G.S.
  • Kwok, C.
  • Gravells, P.
  • Harrison, D.
  • Burke, S.
  • Hallsworth, A.
  • Jamin, Y.
  • George, S.
  • Robinson, S.P.
  • Lord, C.J.
  • Poon, E.
  • Yeomanson, D.
  • Chesler, L.
  • Bryant, H.E. ORCID logo https://orcid.org/0000-0003-2720-7020
Copyright, Publisher and Additional Information: © 2020 The Authors. All site content, except where otherwise noted, is licensed under a Creative Commons Attribution 3.0 License. https://creativecommons.org/licenses/by/3.0/
Keywords: PARP inhibitor; neuroblastoma; MYCN; replication stress; replication fork stalling
Dates:
  • Accepted: 3 October 2019
  • Published: 9 June 2020
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Sheffield Teaching Hospitals
Funding Information:
FunderGrant number
CHILDREN WITH CANCER UK16-217
Depositing User: Symplectic Sheffield
Date Deposited: 24 Jun 2020 08:59
Last Modified: 24 Jun 2020 08:59
Status: Published
Publisher: Impact Journals, LLC
Refereed: Yes
Identification Number: https://doi.org/10.18632/oncotarget.27329

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