Silica nanoparticles induce lung inflammation in mice via ROS/PARP/TRPM2 signaling-mediated lysosome impairment and autophagy dysfunction

Wang, M, Li, J, Dong, S et al. (9 more authors) (2020) Silica nanoparticles induce lung inflammation in mice via ROS/PARP/TRPM2 signaling-mediated lysosome impairment and autophagy dysfunction. Particle and Fibre Toxicology, 17. 23. ISSN 1743-8977

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Copyright, Publisher and Additional Information: © The Author(s). 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data
Keywords: Nanoparticles; Pulmonary inflammation; ROS/PARP/TRPM2 signaling; Lysosomal impairment; Autophagy dysfunction
Dates:
  • Published: December 2020
  • Accepted: 25 May 2020
  • Published (online): 8 June 2020
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Biomedical Sciences (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 17 Jun 2020 14:24
Last Modified: 17 Jun 2020 14:27
Status: Published
Publisher: Biomed Central
Identification Number: https://doi.org/10.1186/s12989-020-00353-3
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