Shear stress activates ADAM10 sheddase to regulate Notch1 via the Piezo1 force sensor in endothelial cells

Caolo, V orcid.org/0000-0001-6215-2702, Debant, M, Endesh, N et al. (6 more authors) (2020) Shear stress activates ADAM10 sheddase to regulate Notch1 via the Piezo1 force sensor in endothelial cells. eLife, 9. ISSN 2050-084X

Abstract

Metadata

Authors/Creators:
Keywords: Ion channel; Notch signalling; Proteinase; Endothelial cell.
Dates:
  • Accepted: 1 June 2020
  • Published (online): 2 June 2020
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM) > Discovery & Translational Science Dept (Leeds)
Funding Information:
FunderGrant number
Wellcome Trust110044/Z/15/Z
British Heart FoundationRG/17/11/33042
EU - European Union748369
Depositing User: Symplectic Publications
Date Deposited: 09 Jun 2020 11:29
Last Modified: 09 Jun 2020 11:29
Status: Published online
Publisher: eLife Sciences Publications, Ltd
Identification Number: https://doi.org/10.7554/elife.50684

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