In silico-guided optimisation of oxygen gradients in hepatic spheroids

Leedale, J., Colley, H.E., Gaskell, H. et al. (5 more authors) (2019) In silico-guided optimisation of oxygen gradients in hepatic spheroids. Computational Toxicology, 12. 100093. ISSN 2468-1113



Copyright, Publisher and Additional Information: © 2019 Elsevier B.V. This is an author produced version of a paper subsequently published in Computational Toxicology. Uploaded in accordance with the publisher's self-archiving policy. Article available under the terms of the CC-BY-NC-ND licence (
Keywords: Liver spheroids; HepG2; HepaRG; Hypoxia; Oxygen gradient; In silico modelling
  • Accepted: 18 June 2019
  • Published (online): 20 June 2019
  • Published: November 2019
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Clinical Dentistry (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 26 May 2020 13:32
Last Modified: 20 Jun 2020 00:39
Status: Published
Publisher: Elsevier BV
Refereed: Yes
Identification Number: