Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response

Xing, M., Wang, X., Palmai-Pallag, T. et al. (4 more authors) (2015) Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response. Oncotarget, 6 (35). pp. 37638-37646.

Abstract

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Authors/Creators:
Copyright, Publisher and Additional Information: © 2015 The Author(s). This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Keywords: DNA replication; Holliday junctions; NBS1; cellular senescence; homologous recombination; Animals; Apoptosis; Cell Proliferation; Cells, Cultured; Cellular Senescence; DNA Damage; DNA Repair; DNA Replication; DNA-Binding Proteins; Endonucleases; Fibroblasts; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; Mice; RNA, Messenger; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; S Phase
Dates:
  • Accepted: 11 September 2015
  • Published (online): 22 September 2015
  • Published: 22 September 2015
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 08 Apr 2020 08:15
Last Modified: 09 Apr 2020 07:14
Status: Published
Publisher: Impact Journals
Refereed: Yes
Identification Number: https://doi.org/10.18632/oncotarget.5497
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