Actis, P orcid.org/0000-0002-7146-1854 and Leach, AR (2020) Single-Entity Electrochemistry at Confined Sensing Interfaces. Science China Chemistry, 63 (5). pp. 589-618. ISSN 1674-7291
Abstract
Measurements at the single-entity level provide more precise diagnosis and understanding of basic biological and chemical processes. Recent advances in the chemical measurement provide a means for ultra-sensitive analysis. Confining the single analyte and electrons near the sensing interface can greatly enhance the sensitivity and selectivity. In this review, we summarize the recent progress in single-entity electrochemistry of single molecules, single particles, single cells and even brain analysis. The benefits of confining these entities to a compatible size sensing interface are exemplified. Finally, the opportunities and challenges of single entity electrochemistry are addressed.
Metadata
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Copyright, Publisher and Additional Information: | © Science China Press and Springer-Verlag GmbH Germany, part of Springer Nature 2020. This is an author produced version of a paper published in Science China Chemistry. Uploaded in accordance with the publisher's self-archiving policy. | ||||||||
Keywords: | single entity; electrochemistry; confining effect; sensors; nanopores; nanoparticles; single cell; brain | ||||||||
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Institution: | The University of Leeds | ||||||||
Academic Units: | The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Electronic & Electrical Engineering (Leeds) > Pollard Institute (Leeds) | ||||||||
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Depositing User: | Symplectic Publications | ||||||||
Date Deposited: | 06 Mar 2020 15:58 | ||||||||
Last Modified: | 17 Jun 2022 15:33 | ||||||||
Status: | Published | ||||||||
Publisher: | Springer | ||||||||
Identification Number: | https://doi.org/10.1007/s11426-020-9716-2 |