Effects of fluoxetine on functional outcomes after acute stroke (FOCUS): a pragmatic, double-blind, randomised, controlled trial

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Authors/Creators:	Dennis, M Mead, G Forbes, J Graham, C Hackett, M Hankey, GJ House, A https://orcid.org/0000-0001-8721-8026 Lewis, S Lundström, E Sandercock, P Innes, K Williams, C Drever, J Mcgrath, A Deary, A Fraser, R Anderson, R Walker, P Perry, D Mcgill, C Buchanan, D Chun, Y Dinsmore, L Maschauer, E Barugh, A Mikhail, S Blair, G Hoeritzauer, I Scott, M Fraser, G Lawrence, K Shaw, A Williamson, J Burgess, D Macleod, M Morales, D Sullivan, F Brady, M French, R Van Wijck, F Watkins, C Proudfoot, F Skwarski, J Mcgowan, D Murphy, R Burgess, S Rutherford, W Mccormick, K Buchan, R Macraild, A Paulton, R Fazal, A Taylor, P Parakramawansha, R Hunter, N Perry, J Bamford, J Waugh, D Veraque, E Bedford, C Kambafwile, M Idrovo, L Makawa, L Smalley, P Randall, M Thirugnana-Chandran, T Hassan, A Vowden, R Jackson, J Bhalla, A Rudd, A Tam, CK Birns, J Gibbs, C Lee Carbon, L Cattermole, E Marks, K Cape, A Hurley, L Kullane, S Smyth, N Eglinton, C Wilson, J Giallombardo, E Frith, A Reidy, P Pitt, M Sykes, L Dellafera, D Croome, V Kerwood, L Hancevic, M Narh, C Merritt, C Duffy, J Cooke, D Willson, J Ali, A Naqvi, A Kamara, C Bowler, H Bell, S Jackson, T Harkness, K Stocks, K Duty, S Doyle, C Dunn, G Endean, K Claydon, F Richards, E Howe, J Lindert, R Majid, A Dakin, K Maatouk, A Barron, L Meegada, M Rana, P Nair, A Brighouse-Johnson, C Greig, J Kyu, M Prasad, S Robinson, M Alam, I Mclean, B Greenhalgh, L Ahmed, Z Roffe, C Brammer, S Beardmore, C Finney, K Barry, A Hollinshead, P Grocott, J Maguire, H Natarajan, I Chembala, J Sanyal, R Lijko, S Abano, N Remegoso, A Ferdinand, P Stevens, S Varquez, R Causley, C Butler, A Whitmore, P Stephen, C Carpio, R Hiden, J Muddegowda, G Denic, H Sword, J Curwen, R James, M Mudd, P Hall, F Cageao, J Keenan, S Roughan, C Kingwell, H Hemsley, A Lohan, C Davenport, S Bowring, A Chapter, T Hough, M Strain, D Gupwell, K Miller, K Goff, A Cusack, E Todd, S Partridge, R Jennings, G Thorpe, K Stephenson, J Littlewood, K Barber, M Brodie, F Marshall, S Esson, D Coburn, I Mcinnes, C Ross, F Bowie, E Barcroft, H Withers, V Miller, L Willcoxson, P Donninson, M Evans, R Daniel, D Coyle, J Keeling, M Wanklyn, P Elliott, M Wightman, J Iveson, E Dyer, N Porteous, A-M Haritakis, M Ward, M Doughty, L Carr, L O Neill, M Anazodo, C Wood, P Cottrell, P Donne, C Rodriguez, R Mir, R Westmoreland, J Bell, J Emms, C Wright, L Clark Brown, P Bamford, E Stanners, A Carpenter, M Datta, P Davey, R Needle, A Eastwood, MJ Razik, FZ Ghouri, I Bateman, G Archer, J Balasubramanian, V Bowers, R Ball, J Benton, L Jackson, L Ellam, J Norton, K Guyler, P Dowling, T Tysoe, S Harman, P Kundu, A Omodunbi, O Loganathan, T Chandler, S Noor, S Siddiqui, A Siddiqui, A Kunhunny, S Sinha, D Sheppard, M Rashmi, S France, E Orath Prabakaran, R Wilson, L Ropun, A Kelavkar, S Ng, KX Kamuriwo, L Shah, S Mangion, D Constantin, C De Michele Hock, L Hardwick, A Borley, J Markova, S Netherton, K Lawrence, T Fletcher, J Spencer, R Palmer, H Cullen, C Hamill, D Durairaj, R Mellor, Z Fluskey, T Wood, D Keeling, A Hankin, V Peters, J Shackcloth, D Hlaing, T Tangney, R Ewing, J Harrison, M Stevenson, S Sutton, V Soliman, M Hindle, J Watson, E Hewitt, C Borley, J Butler, S Wahishi, I Arif, S Fields, A Sharma, J Brown, R Taylor, C Bell, S Leach, S Patterson, C Khan, S Wilson, H Price, J Ramadan, H Maguire, S Bellfield, R Hooley, M Hamid, U Gaba, W Ghulam, R Masters, L Quinn, O Sekaran, L Tate, M Mohammed, N Bharaj, K Justin, F Pattni, R Alwis, L Sethuraman, S Robinson, R Eldridge, L Mintias, S Chauhan, M Tam, C-K Palmones, J Holmes, C Guthrie, LB Osborn, M Ball, L Caine, S Steele, A Murphy, P Devitt, N Leonard, J Patel, R Penwarden, I Dodd, E Holloway, A Baker, P Clarke, S Williams, S Dow, L Wynn-Williams, R Kennedy, J Teal, R Schulz, U Ford, G Mathieson, P Reckless, I Deveciana, A Mccann, P Cluckie, G Howell, G Ayer, J Moynihan, B Ghatala, R Clarke, B Cloud, G Patel, B Khan, U Al-Samarrai, N Trippier, S Chopra, N Adedoyin, T Watson, F Jones, V Zhang, L Choy, L Williams, R Clarke, N Blight, A Kennedy, K Dainty, A Selvarajah, J Kalladka, D Cheripelli, B Smith, W Moreton, F Welch, A Huang, X Douglas, E Lush, A Day, N El Tawil, S Montgomery, K Hamilton, H Ritchie, D Ramachandra, S Mcleish, K Thavanesan, K Loganathan, S Roberts, J Cox, C Orr, S Hogan, A Tiwari, D Hann, G Longland, B David, O Bell, J Ovington, C Rogers, E Bower, R Keltos, M Cohen, D Devine, J Alwis, L Southworth, L Burgess, L Lang, M Badiani, B Guo, F Oshodi, A Owoyele, E Epie, N David, A Mpelembue, M Bathula, R Abdul-Saheb, M Chamberlain, A Sudkeo, V Rashed, K Wood, D Williams-Yesson, B Board, J De Bruijn, S Buckley, C Board, S Allison, J Keeling, E Duckett, T Donaldson, D Vickers, C Barron, C Balian, L Wilson, J Edwards, A England, T Hedstrom, A Bedford, E Harper, M Melikyan, E Abbott, W Subramanian, K Goldsworthy, M Srinivasan, M Yeomans, A Donaldson, D Hurford, F Chapman, R Shahzad, S David, O Motherwell, N Tonks, L Young, R Ghani, U Mukherjee, I Dutta, D Obaid, M Brown, P Davis, F Ward, D Turfrey, J Cartwright, B Topia, B Spurway, J Collins, K Bakawala, R Hughes, C Oconnell, S Hill, L Chatterjee, K Webster, T Haider, S Rushworth, P Macleod, F Nallasivan, A Perkins, C Burns, E Leason, S Carter, T Seagrave, S Sami, E Armstrong, L Naqvi, SN Hassan, M Parkinson, S Mawer, S Darnbrook, G Booth, C Hairsine, B Smith, M Williamson, S Farquhar, F Esisi, B Cassidy, T Mankin, G Mcclelland, B Bokhari, M Sproates, D Epstein, E Hurdowar, S Blackburn, R Sukhdeep, N Razak, S Osman, K Hashmi, A Upton, N Harrington, F Courtauld, G Schofield, C Lucas, L Adie, K Bond, K Mate, A Skewes, J James, A Brodie, C Johnson, M Allsop, L Driver, E Harris, K Drake, M Ellis, S Maund, B Thomas, E Moore, K Burn, M Hamilton, A Mahalingam, S Misra, A Reid, F Benford, A Hilton, D Hazell, L Ofori, K Thomas, AL Mathew, M Dayal, S Burn, I Fotherby, K Jennings-Preece, K Willberry, A Morgan, D Butler, D Sahota, G Kauldhar, K Ahmad, N Stevens, A Das, S Bruce, D Pai, Y Nyo, K Stephenson, L Nendick, R Rogers, G Dhakal, M Dima, S Brown, E Clayton, S Gamble, P Naeem, M Hayman, R Burnip, R Earnshaw, P Hargroves, D Ransom, B Rudenko, H Balogun, I Griffiths, K Mears, K Webb, T Cowie, L Hammond, T Thomson, A Ceccarelli, D Chattha, N Beranova, E Verrion, A Gillian, A Schumacher, N Bahk, A Walker, S Cvoro, V Mccormick, K Chapman, N Pound, S Cain, R Mcauley, S Couser, M Simpson, M Tachtatzis, A Ullah, K Sims, D Jones, R Smith, J Tongue, R Willmot, M Sutton, C Littleton, E Khaira, J Maiden, S Cunningham, J Green, C Chin, Y-M Bates, M Ahlquist, K Kane, I Breeds, J Sargent, T Latter, L Pitt Ford, A Gainsborough, N Levett, T Thompson, P Barbon, E Dunne, A Hervey, S Ragab, S Sandell, T Dickson, C Dube, J Power, S Evans, N Wadams, B Elitova, S Aubrey, B Garcia, T Mcilmoyle, J Jeffs, C Dickinson, C Ahmed, A Kumar, S Frudd, J Armer, C Potter, A Donaldson, S Howard, J Jones, K Dhar, S Collas, D Sundayi, S Denham, L Oza, D Walker, E Cunningham, J Bhandari, M Ispoglou, S Evans, R Sharobeem, K Walton, E Shanu, S Hayes, A Howard-Brown, J Billingham, S Weir, N Pressly, V Wood, E Sykes, L Howard, G Burton, H Crawford, P Egerton, S Evans, S Hakkak, J Andrews, J Lampard, R Allen, C Walters, A Said, R Marigold, JR Tsang, S-M Creeden, R Cox, C Smith, S Gartrell, I Smith, F Jenkins, C Pryor, J Hedges, A Price, F Moseley, L Mercer, L Hughes, C Mcgowan, D Azim, A White, J Krasinska-Chavez, M Chaplin, S Curtis, J Singh, D Imam, J Nicolson, A Alam, S Whitworth, S Wood, L Warburton, E Kelly, S Mcgee, J Markus, H Chandrasena, D Hayden, D Sesay, J Hayhoe, H Bolton, M Macdonald, J Mitchell, J Farron, C Amis, E Day, D Culbert, A Espanol, A Hannon, N Handley, D Finlay, S Crisp, S Whitehead, L Francis, J Oconnell, J Osborne, E Beard, R Krishnamurthy, R Mokoena, L Sattar, N Myint, M Edwards, M Smith, A Corrigan, P Byrne, A Blackburn, J Mcghee, C Smart, A Macleod, M Donaldson, F Copeland, C Wilson, J Scott, R Fitzsimmons, P Lopez, P Wilkinson, M Manoj, A Cox, P Trainor, L Fletcher, G Denny, L Kavanagh, K Allsop, H Emsley, H Sultan, S Mcloughlin, A Walmsley, B Hough, L Ahmed, S Doyle, D Gregary, B Raj, S Nagaratnam, K Mannava, N Haque, N Shields, N Preston, K Mason, G Short, K Lumsdale, G Uitenbosch, G Sukys, U Valentine, S Jarrett, D Dodsworth, K Wands, M Khan, N Tandy, J Watkinson, C Golding, W Butler, R Williams, M Davies, Y Yip, K James, C Suttling, A Maney, A Gamble, GE Hague, A Charles, B Blane, S Duran, B Lambert, C Stagg, K Whiting, R Homan, JE Brown, S Hussain, M Harvey, M Graham, L Foote, L Lane, C Kemp, LJ Rowe, J Durman, H Foot, J Brotherton, L Hunt, N Pawley, C Whitcher, A Sutton, P Mcdonald, S Pak, D Wiltshire, A Jagger, J Metcalf, AK Healey, GL Balami, J Self, CM Crofts, M Chakrabarti, A Hmu, C Ravenhill, G Grimmer, C Soe, T Keshet-Price, J Langley, M Potter, I Tam, P-L Macleod, MJ Cooper, P Christie, M Irvine, J Annison, F Christie, D Meneses, C Johnson, A Joyson, A Nelson, S Taylor, V Reid, J Clarke, R Furnace, J Gow, H Abousleiman, Y Beadling, T Collins, S Jones, S Purcell, J Bloom, S Goshawk, S Landicho, M Sangaralingham, S Begum, Y Mutton, S Munuswamy Vaiyapuri, E Allen, J Lowe, J Hughes, M Wiggam, I Cuddy, S Tauro, S Wells, B Mohd Nor, A Eglinton, C Persad, N Kalita, M Weatherby, S Brown, C Pace, A Lashley, D Marner, M Weinling, M Wilmshurst, N Waugh, D Mucha, A Shah, A Baker, J Westcott, J Cowan, R Vasileiadis, E Mumani, S Parry, A Mason, C Holden, M Petrides, K Nishiyama, T Mehta, H Krishnan, M Lynne, D Thomas, L Lynda, C Hughes, C Clements, C Williams, R Anjum, T Sharon, S Tucker, S Jones, P Colwill, D Thompson Jones, H Chadha, D Fairweather, M Walstow, D Fong, R Johnston, S Almadenboyle, C Ross, S Carson, S Nair, P Tenbruck, E Stirling, M Pusalkar, A Beadle, H Chan, K Dangri, P Asokanathan, A Rana, A Gohil, S Massyn, M Aruldoss, P Cook, A Crabtree, K Dabbagh, S Black, T Clarke, C Mead, D Fennelly, R Anthony, A Nardone, L Dimartino, V Tribbeck, M Broughton, D Tryambake, D Dixon, L Skotnicka, A Thompson, J Whitehouse, S Sigsworth, A Wong, J Annamalai, A Pagan, J Affley, B Sunderland, C Goldenberg, L Khan, A Wilkinson, P Nari, R Abbott, L Young, E Shakhon, A Lock, S Stewart, J Pereira, R Dsouza, M Dunn, S Mckenna, A-M Cron, N Kidd, M Hull, G Bunworth, K Drummond, G Mahawish, K Hayes, N Connell, L Simpson, J Penney, H Punekar, S Nevinson, J Wareing, W Ward, J Greenwood, R Austin, D Banaras, A Hogan, C Corbett, T Oji, N Elliott, E Brezitski, M Passeron, N Howaniec, L Watchurst, C Patel, K Erande, R Shah, R Sengupta, N Metiu, M Gonzalez, C Funnell, S Margalef, J Peters, G Chadbourn, I Sivakumar, R Saksena, R Ketley-O'donel, J Needle, R Chinery, E Wright, A Cook, S Ngeh, J Proeschel, H Cook, P Ashcroft, P Sharpe, S Jones, S Jenkinson, D Kelly, D Bray, H Gunathilagan, G Griffiths, K Mears, K Gillian, A Jones, S Tilbey, S Abubakar, S Beranova, E Vassallo, J Leonard, D Orrell, L Hasan, A Khan, A Qamar, S Graham, S Hewitt, E Awolesi, J Haque, M Kent, A Bradshaw, E Cooper, M Wynter, I Rajapakse, A Janbieh, J Nasar, AM Wade, L Otter, L Haigh, S Burgoyne, J-R Boulton, R Boulton, A Rayessa, R Clarkson, E Rhian, H Fleming, A Mitchelson, K Lowthorpe, V Abdul-Hamid, A Jones, P Duggan, C Hynes, A Nurse, E Raza, SA Jones, S Pallikona, U Edwards, B Morgan, G Dennett, K Tench, H Loosley, R Trugeon-Smith, T Jones, R Williams, R Robson, D Mavinamane, S Meenakshisundaram, S Ranga, L Dealing, S Hill, A Hargreaves, M Smith, T Bate, J Harrison, L Kirthivasan, R Cannon, E Topliffe, J Keskeys, R Williams, S Mcneela, F Cairns, F James, T Lyle, A Shah, S Zachariah, G Fergey, L Smolen, S Cooper, L Bohannan, E Omer, S Amlani, S Hunter, N Hawkes-Blackburn, M Gulli, G Peacocke, A Amero, J Burova, M Speirs, O Levy, S Francis, L Holland, S Brotheridge, S Lyon, H Hare, C Jackson, S Stephenson, L Al Hussayni, S Featherstone, J Bwalya, A Singh, A Goorah, MN Walford, J Bell, A Kelly, C Rusk, D Sutton, D Patel, F Duberley, S Hayes, K Hunt, L El Nour, A Cottrell, P Westmoreland, J Honour, S Box, C Wood, P Haritakis, M Dyer, S Brown, L Elliott, K Temlett, E Paterson, J Furness, R Young, S Orugun, E Brewer, C Thornthwaite, S Crowther, H Glover, R Sein, M Haque, K Gibson, E Wong, S Rotchell, K Burton, K Brookes, L Bailey, L Leonard, D Lindley, C Murray, A Waltho, K Holland, M Kumar, P Harlekar, P Booth, L Culmsee, C Drew, J Khan, M Mackenzie, N Thomas, C Ritchie, J Barker, J Haley, M Cotterill, D Lane, L Little, C Simmons, D Saunders, G Dymond, H Kidd, S Warinton, R Neves-Silva, Y Nevajda, B Villaruel, M Umasankar, U Patel, S Man, A Christmas, N Rangasamy, R Ladner, R Butt, G Alvares, W Gadi, N Power, M Wroath, B Dynan, K Wilson, D Crothers, S Leonard, C Hagan, S Douris, G Vahidassr, D Thompson, A Gallen, B Mckenna, S Edwards, C Mcgoldrick, C Bhattad, M Kawafi, K Morse, D Jacob, P Turner, L Saravanan, N Johnson, L Humphrey, S Namushi, R Patel, R Mclaughlin, J Omahony, P Osikominu, E Orefo, C Mcdonald, C Jones, V Makanju, E Khan, T Appiatse, G Stone, H Augustin, M Wardale, A Salehin, M Bailey, D Garcia-Alen, L Kalathil, L Tinsley, S Jones, T Amor, K Ritchings, A Margerum, E Horton, J Miller, R Gautam, N Meir, J Jones, A Putteril, J Lepore, M Makanju, E Gallifent, R Arundell, L-L Mcredmond, C Goulding, A Nadarajan, V Laurence, J Fung Lo, S Melander, S Nicholas, P Woodford, E Mckenzie, G Le, V Crause, J Luder, R Bhargava, M Shah, R Bhome, G Johnson, VV Chesser, D Bridger, H Murali, E Scott, J Morrison, S Burns, A Graham, J Duffy, M Ali, K Sargent, T Pitcher, E Gaylard, J Newman, J Punnoose, S Besley, S Purohit, K Rees, A Davy, M Chohan, O Khan, MF Walker, R Murray, V Bent, C Oakley, S Blight, A Peixoto, C Jones, S Livingstone, G Butler, F Bradfield, S Gordon, L Schmit, J Wijewardane, A Edmunds, T Wills, R Medcalf, C Argandona, L Cuenoud, L Hassan, H Erumere, E Ocallaghan, A Gompertz, P Redjep, O Auld, G Howaniec, L Song, A Tarkas, T Kabash, H Hungwe, R
Copyright, Publisher and Additional Information:	© 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 license.
Dates:	Published (online): 5 December 2018 Published: 19 January 2019
Institution:	The University of Leeds
Academic Units:	The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Health Sciences (Leeds) > Academic Unit of Psychiatry and Behavioural Sciences (Leeds)
Depositing User:	Symplectic Publications
Date Deposited:	03 Mar 2020 12:11
Last Modified:	03 Mar 2020 12:11
Status:	Published
Publisher:	Elsevier BV
Identification Number:	https://doi.org/10.1016/s0140-6736(18)32823-x

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