Metabolic Reprograming of Cystic Fibrosis Macrophages via the IRE1α Arm of the Unfolded Protein Response Results in Exacerbated Inflammation

Lara-Reyna, S, Scambler, T, Holbrook, J et al. (6 more authors) (2019) Metabolic Reprograming of Cystic Fibrosis Macrophages via the IRE1α Arm of the Unfolded Protein Response Results in Exacerbated Inflammation. Frontiers in Immunology, 10. 1789. ISSN 1664-3224

Abstract

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Authors/Creators:
Copyright, Publisher and Additional Information: © 2019 Lara-Reyna, Scambler, Holbrook, Wong, Jarosz-Griffiths, Martinon, Savic, Peckham and McDermott. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
Keywords: cystic fibrosis; inflammation; metabolism; IRE1; XBP1; UPR; macrophages
Dates:
  • Accepted: 16 July 2019
  • Published (online): 2 August 2019
  • Published: 2 August 2019
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Medicine and Health (Leeds) > Institute of Molecular Medicine (LIMM) (Leeds) > Section of Translational Medicine (Leeds)
Funding Information:
FunderGrant number
Cystic Fibrosis TrustSRC009
Depositing User: Symplectic Publications
Date Deposited: 20 Aug 2019 13:20
Last Modified: 20 Aug 2019 13:20
Status: Published
Publisher: Frontiers Media
Identification Number: https://doi.org/10.3389/fimmu.2019.01789

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