Bubici, C, Lepore, A orcid.org/0000-0002-2037-673X and Papa, S orcid.org/0000-0002-8369-6538 (2019) ASKing No More: The Emerging Role of Dual‐Specific Phosphatase 12 in the Regulation of Hepatic Lipid Metabolism. Hepatology, 70 (4). pp. 1091-1094. ISSN 0270-9139
Abstract
Accumulation of fat in liver cells not due to alcohol abuse is the hallmark of non‐alcoholic fatty liver disease (NAFLD), a common condition that may progress to non‐alcoholic steatohepatitis (NASH) characterized by liver inflammation.(1) Over a long period of time, NASH may lead to fibrosis with consequent cirrhosis, which in turn predisposes patients to hepatocellular carcinoma.
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Copyright, Publisher and Additional Information: | © 2019 by the American Association for the Study of Liver Diseases.. All rights reserved. This is the post-peer reviewed version of the following article: Bubici, C. , Lepore, A. and Papa, S. (2019), ASKing No More: The Emerging Role of Dual‐Specific Phosphatase 12 in the Regulation of Hepatic Lipid Metabolism. Hepatology, 70: 1091-1094, which has been published in final form at https://doi.org/10.1002/hep.30851. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. | ||||
Keywords: | mitogen‐activated protein kinase; ASK1; nonalcoholic fatty liver disease; hepatic lipid metabolism | ||||
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Institution: | The University of Leeds | ||||
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Depositing User: | Symplectic Publications | ||||
Date Deposited: | 17 Jul 2019 13:31 | ||||
Last Modified: | 12 Jul 2020 00:38 | ||||
Status: | Published | ||||
Publisher: | Wiley | ||||
Identification Number: | https://doi.org/10.1002/hep.30851 |