Cell-active Small Molecule Inhibitors of the DNA-damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG) : Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides

Waszkowycz, Bohdan, Smith, Kate M., McGonagle, Alison E. et al. (17 more authors) (2018) Cell-active Small Molecule Inhibitors of the DNA-damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG) : Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides. JOURNAL OF MEDICINAL CHEMISTRY. pp. 10767-10792. ISSN 0022-2623

Metadata

Authors/Creators:
  • Waszkowycz, Bohdan
  • Smith, Kate M.
  • McGonagle, Alison E.
  • Jordan, Allan M.
  • Acton, Ben
  • Fairweather, Emma E.
  • Griffiths, Louise A.
  • Hamilton, Niall M.
  • Hamilton, Nicola S.
  • Hitchin, James R.
  • Hutton, Colin P.
  • James, Dominic I.
  • Jones, Clifford D.
  • Jones, Stuart
  • Mould, Daniel P.
  • Small, Helen F.
  • Stowell, Alexandra I. J.
  • Tucker, Julie Ann ORCID logo https://orcid.org/0000-0002-6119-676X
  • Waddell, Ian D.
  • Ogilvie, Donald J.
Copyright, Publisher and Additional Information: © 2018 American Chemical Society. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details.
Dates:
  • Accepted: 7 November 2018
  • Published (online): 7 November 2018
  • Published: 13 December 2018
Institution: The University of York
Academic Units: The University of York > Faculty of Sciences (York) > Biology (York)
Depositing User: Pure (York)
Date Deposited: 03 Jul 2019 09:30
Last Modified: 29 Apr 2023 23:13
Published Version: https://doi.org/10.1021/acs.jmedchem.8b01407
Status: Published
Refereed: Yes
Identification Number: https://doi.org/10.1021/acs.jmedchem.8b01407

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