The SPECTRA Collaboration OMERACT Working Group: Criterion Validity of Joint Space Outcomes with High Resolution Peripheral Quantitative Computed Tomography

Abstract

Objective: We assessed construct validity of high-resolution peripheral quantitative computed tomography (HR-pQCT) joint space outcomes by comparison with radiographs in patients with rheumatoid arthritis.

Methods: In 43 patients, quantitative, volumetric, HR-pQCT measurements were compared with ordinal Sharp/van der Heijde scoring (SvdH) in the 2nd and 3rd metacarpophalangeal joints.

Results: Generalized estimating equations showed that joint space minimum, SD, and asymmetry by HR-pQCT were associated with SvdH scores (p < 0.05). There was a considerable range in HR-pQCT measurements at SvdH equal to 0.

Conclusion: HR-pQCT demonstrated construct validity outcomes and provides improved 3-D visualization of joint space.

Metadata

Authors/Creators:	Manske, SL Brunet, SC Finzel, S Stok, KS Conaghan, PG https://orcid.org/0000-0002-3478-5665 Boyd, SK Barnabe, C
Copyright, Publisher and Additional Information:	© 2019 The Journal of Rheumatology. This is a pre-copyediting, author-produced PDF of an article accepted for publication in The Journal of Rheumatology following peer review. The definitive publisher-authenticated version is available online at: https://doi.org/10.3899/jrheum.180870.
Keywords:	rheumatoid arthritis, outcome assessment, radiography, computed tomography, metacarpophalangeal joint
Dates:	Accepted: 13 November 2018 Published (online): 15 January 2019 Published: October 2019
Institution:	The University of Leeds
Academic Units:	The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Institute of Rheumatology & Musculoskeletal Medicine (LIRMM) (Leeds) > Musculoskeletal Medicine & Imaging (Leeds)
Depositing User:	Symplectic Publications
Date Deposited:	19 Nov 2018 14:49
Last Modified:	15 Jan 2020 01:39
Status:	Published
Publisher:	Journal of Rheumatology
Identification Number:	https://doi.org/10.3899/jrheum.180870

CORE (COnnecting REpositories)

The SPECTRA Collaboration OMERACT Working Group: Criterion Validity of Joint Space Outcomes with High Resolution Peripheral Quantitative Computed Tomography

Abstract

Metadata

Download

Accepted Version

Export

Statistics