Li, W., Song, W., Chen, B. et al. (1 more author) (2018) Superparamagnetic graphene quantum dot as a dual-modality contrast agent for confocal fluorescence microscopy and magnetomotive optical coherence tomography. Journal of Biophotonics. e201800219. ISSN 1864-063X
Abstract
A magnetic graphene quantum dot (MGQD) nanoparticle, synthesized by hydrothermally reducing and cutting graphene oxide-iron oxide sheet, was demonstrated to possess the capabilities of simultaneous confocal fluorescence and magnetomotive OCT imaging. This MGQD shows low toxicity, significant tunable blue fluorescence and superparamagnetism, which can thus be used as a dual-modality contrast agent for confocal fluorescence microscopy (CFM) and magnetomotive OCT (MMOCT). The feasibility of applying MGQD as a tracer of cells is shown by imaging and visualizing MGQD labelled cells using CFM and our in-house MMOCT. Since MMOCT and CFM can offer anatomical structure and intracellular details respectively, the MGQD for cell tracking could provide a more comprehensive diagnosis. This article is protected by copyright. All rights reserved.
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Copyright, Publisher and Additional Information: | © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. This is an author produced version of a paper subsequently published in Journal of Biophotonics. Uploaded in accordance with the publisher's self-archiving policy. | ||||||||
Keywords: | contrast agent; fluorescence microscopy; graphene; magnetomotive optical coherence tomography; quantum dot | ||||||||
Dates: |
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Institution: | The University of Sheffield | ||||||||
Academic Units: | The University of Sheffield > Faculty of Engineering (Sheffield) > Department of Electronic and Electrical Engineering (Sheffield) | ||||||||
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Depositing User: | Symplectic Sheffield | ||||||||
Date Deposited: | 29 Oct 2018 11:06 | ||||||||
Last Modified: | 06 Sep 2019 00:39 | ||||||||
Published Version: | https://doi.org/10.1002/jbio.201800219 | ||||||||
Status: | Published online | ||||||||
Publisher: | Wiley | ||||||||
Refereed: | Yes | ||||||||
Identification Number: | https://doi.org/10.1002/jbio.201800219 | ||||||||
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