Fixation and Spread of Somatic Mutations in Adult Human Colonic Epithelium

Nicholson, AM, Olpe, C, Hoyle, A et al. (17 more authors) (2018) Fixation and Spread of Somatic Mutations in Adult Human Colonic Epithelium. Cell Stem Cell, 22 (6). 909-918.e8. ISSN 1934-5909



  • Nicholson, AM
  • Olpe, C
  • Hoyle, A
  • Thorsen, A-S
  • Rus, T
  • Colombé, M
  • Brunton-Sim, R
  • Kemp, R
  • Marks, K
  • Quirke, P ORCID logo
  • Malhotra, S
  • Ten Hoopen, R
  • Ibrahim, A
  • Lindskog, C
  • Myers, MB
  • Parsons, B
  • Tavaré, S
  • Wilkinson, M
  • Morrissey, E
  • Winton, DJ
Copyright, Publisher and Additional Information: © 2018 The Authors. Published by Elsevier Inc. This is an open access article under the terms of the Creative Commons Attribution License (CC-BY 4.0), which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited. To view a copy of this license, visit
Keywords: human; colon; epithelium; crypt; stem cells; dynamics; mutation; clone; fission; expansion
  • Accepted: 23 April 2018
  • Published (online): 17 May 2018
  • Published: 1 June 2018
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cancer and Pathology (LICAP) > Pathology & Tumour Biology (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 26 Apr 2018 11:08
Last Modified: 25 Jun 2023 21:19
Status: Published
Publisher: Elsevier
Identification Number: