Preoperative chemoradiation with capecitabine, irinotecan and cetuximab in rectal cancer: significance of pre-treatment and post-resection RAS mutations

Gollins, S, West, N orcid.org/0000-0002-0346-6709, Sebag-Montefiore, D et al. (17 more authors) (2017) Preoperative chemoradiation with capecitabine, irinotecan and cetuximab in rectal cancer: significance of pre-treatment and post-resection RAS mutations. British Journal of Cancer, 117. pp. 1286-1294. ISSN 0007-0920

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Copyright, Publisher and Additional Information: © The Author(s) named above. This is an open access article under the terms of the Creative Commons Attribution License (CC-BY 4.0), which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
Keywords: locally advanced rectal cancer; cetuximab-containing chemoradiation; RAS mutations; intra-tumoural clonal heterogeneity; treatment response; next generation sequencing
Dates:
  • Accepted: 1 August 2017
  • Published (online): 31 August 2017
  • Published: 24 October 2017
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cancer and Pathology (LICAP) > Pathology & Tumour Biology (Leeds)
Funding Information:
FunderGrant number
Yorkshire Cancer ResearchL386
Depositing User: Symplectic Publications
Date Deposited: 06 Sep 2017 09:47
Last Modified: 21 Mar 2018 16:04
Status: Published
Publisher: Springer Nature
Identification Number: https://doi.org/10.1038/bjc.2017.294

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