Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors

Arce Vargas, F, Furness, AJS, Solomon, I et al. (83 more authors) (2017) Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors. Immunity, 46 (4). pp. 577-586. ISSN 1074-7613

Abstract

Metadata

Authors/Creators:
  • Arce Vargas, F
  • Furness, AJS
  • Solomon, I
  • Joshi, K
  • Mekkaoui, L
  • Lesko, MH
  • Miranda Rota, E
  • Dahan, R
  • Georgiou, A
  • Sledzinska, A
  • Ben Aissa, A
  • Franz, D
  • Werner Sunderland, M
  • Wong, YNS
  • Henry, JY
  • O'Brien, T
  • Nicol, D
  • Challacombe, B
  • Beers, SA
  • Spain, L
  • Wotherspoon, A
  • Francis, N
  • Smith, M
  • Strauss, D
  • Hayes, A
  • Soultati, A
  • Stares, M
  • Spain, L
  • Lynch, J
  • Fotiadis, N
  • Fernando, A
  • Hazell, S
  • Chandra, A
  • Pickering, L
  • Rudman, S
  • Chowdhury, S
  • Swanton, C
  • Jamal-Hanjani, M
  • Veeriah, S
  • Shafi, S
  • Czyzewska-Khan, J
  • Johnson, D
  • Laycock, J
  • Bosshard-Carter, L
  • Goh, G
  • Rosenthal, R
  • Gorman, P
  • Murugaesu, N
  • Hynds, RE
  • Wilson, G
  • Birkbak, NJ
  • Watkins, TBK
  • McGranahan, N
  • Horswell, S
  • Mitter, R
  • Escudero, M
  • Stewart, A
  • Van Loo, P
  • Rowan, A
  • Xu, H
  • Turajlic, S
  • Hiley, C
  • Abbosh, C
  • Goldman, J
  • Stone, RK
  • Denner, T
  • Matthews, N
  • Elgar, G
  • Ward, S
  • Biggs, J
  • Costa, M
  • Begum, S
  • Phillimore, B
  • Chambers, T
  • Nye, E
  • Graca, S
  • Al Bakir, M
  • Hartley, JA
  • Lowe, HL
  • Herrero, J
  • Lawrence, D
  • Hayward, M
  • Panagiotopoulos, N
  • Kolvekar, S
  • Falzon, M
  • Borg, E
Copyright, Publisher and Additional Information: © 2017 The Authors. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Dates:
  • Published: 18 April 2017
  • Accepted: 9 February 2017
  • Published (online): 11 April 2017
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine (Sheffield) > Division of Genomic Medicine (Sheffield) > Department of Oncology (Sheffield)
The University of Sheffield > Sheffield Teaching Hospitals
Depositing User: Symplectic Sheffield
Date Deposited: 01 Jun 2017 15:29
Last Modified: 01 Jun 2017 15:29
Published Version: http://doi.org/10.1016/j.immuni.2017.03.013
Status: Published
Publisher: Elsevier (Cell Press)
Refereed: Yes
Identification Number: https://doi.org/10.1016/j.immuni.2017.03.013

Share / Export

Statistics