Signalling mechanisms mediating Zn2+-induced TRPM2 channel activation and death cell in microglial cells

Syed Mortadza, S, Sim, JA, Stacey, M orcid.org/0000-0003-3502-5542 et al. (1 more author) (2017) Signalling mechanisms mediating Zn2+-induced TRPM2 channel activation and death cell in microglial cells. Scientific Reports, 7. 45032. ISSN 2045-2322

Abstract

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Copyright, Publisher and Additional Information: © The Author(s) 2017. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
Keywords: microglia; TRPM2; ROS; Zn2+; cell death; PKC; NOX; PYK2; ERK
Dates:
  • Published: 21 March 2017
  • Accepted: 20 February 2017
  • Published (online): 21 March 2017
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Biomedical Sciences (Leeds)
The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Molecular and Cellular Biology (Leeds)
Funding Information:
FunderGrant number
Alzheimer's Research UKART/PPG2009A/2
Depositing User: Symplectic Publications
Date Deposited: 16 Mar 2017 11:33
Last Modified: 05 Oct 2017 16:19
Status: Published
Publisher: Nature Publishing Group
Identification Number: https://doi.org/10.1038/srep45032

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