Saha, S, Yoshikai, T, Liu, C-Y et al. (3 more authors) (2015) Fabrication of Cell Hydroxyapatite Nanocrystal Composites Assisted with Layer-by-layer Nanometer-sized Extracellular Matrix Films on Individual Stem Cells. Chemistry Letters, 44 (12). pp. 1714-1716. ISSN 0366-7022
Abstract
The ability to control cell function is one of the challenges for cell-based therapy in regenerative medicine. In this study, we describe a novel method to fabricate cell–hydroxyapatite (HAp) nanocrystal composites to modulate cellular microenvironment. By preparation of layer-by-layer nanometer-sized extracellular matrix films onto cell surfaces, HAp nanocrystals were fabricated onto cell surfaces without cytotoxicity. This technology can modulate cellular functions such as adhesion, growth, and differentiation.
Metadata
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Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Dentistry (Leeds) > Oral Biology (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 28 Jul 2016 15:47 |
Last Modified: | 03 Nov 2016 06:05 |
Published Version: | http://doi.org/10.1246/cl.150854 |
Status: | Published |
Publisher: | Chemical Society of Japan |
Identification Number: | https://doi.org/10.1246/cl.150854 |
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