Harrity, J.P., Allen, B. and Connolly, M. (2016) A Pd-Catalyzed Synthesis of Functionalized Piperidines. Chemistry - A European Journal, 22 (37). pp. 13000-13003. ISSN 0947-6539
Abstract
A readily available cyclic carbamate 1 functions as a general precursor to a range of functionalized piperidine products via a new Pd-catalyzed annulation strategy. An asymmetric catalytic variant provides a rapid and efficient means to access these heterocycles with high to excellent levels of enantiocontrol. Finally, these richly functionalized compounds are amenable to further chemoselective elaboration.
Metadata
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Copyright, Publisher and Additional Information: | © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. This is an author produced version of a paper subsequently published in Chemistry - A European Journal. Uploaded in accordance with the publisher's self-archiving policy. | ||||
Keywords: | Pd-catalysis; annulation; enantioselective; piperidine | ||||
Dates: |
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Institution: | The University of Sheffield | ||||
Academic Units: | The University of Sheffield > Faculty of Science (Sheffield) > Department of Chemistry (Sheffield) | ||||
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Depositing User: | Symplectic Sheffield | ||||
Date Deposited: | 15 Jun 2016 12:29 | ||||
Last Modified: | 08 Jun 2017 00:38 | ||||
Published Version: | http://dx.doi.org/10.1002/chem.201602586 | ||||
Status: | Published | ||||
Publisher: | John Wiley & Sons | ||||
Refereed: | Yes | ||||
Identification Number: | https://doi.org/10.1002/chem.201602586 | ||||
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