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Number of items: 34.


Wang, M, Li, J, Dong, S et al. (9 more authors) (2020) Silica nanoparticles induce lung inflammation in mice via ROS/PARP/TRPM2 signaling-mediated lysosome impairment and autophagy dysfunction. Particle and Fibre Toxicology, 17. 23. ISSN 1743-8977

Caseley, EA, Muench, SP and Jiang, L-H (2020) Contribution of Val/Ile87 residue in the extracellular domain in agonist-induced current responses of the human and rat P2X7 receptors. Purinergic Signalling. ISSN 1573-9538 (In Press)

Brisson, L, Chadet, S, Lopez-Charcas, O et al. (12 more authors) (2020) P2X7 Receptor Promotes Mouse Mammary Cancer Cell Invasiveness and Tumour Progression, and Is a Target for Anticancer Treatment. Cancers, 12 (9). 2342. ISSN 2072-6694

Mousawi, F, Peng, H, Li, J et al. (5 more authors) (2020) Chemical activation of the Piezo1 channel drives mesenchymal stem cell migration via inducing ATP release and activation of P2 receptor purinergic signalling. Stem Cells, 38 (3). pp. 410-421. ISSN 1066-5099

Wang, L, Wei, L, Ding, R et al. (9 more authors) (2020) Predisposition to Alzheimer’s and age-related brain pathologies by PM2.5 exposure: perspective on the roles of oxidative stress and TRPM2 channel. Frontiers in Physiology, 11. 155. ISSN 1664-042X

Jia, X, Su, H, Chen, X et al. (8 more authors) (2020) A critical role of the KCa3.1 channel in mechanical stretch‐induced proliferation of rat bone marrow‐derived mesenchymal stem cells. Journal of Cellular and Molecular Medicine. ISSN 1582-1838

Mai, C, Mankoo, H, Wei, L et al. (4 more authors) (2020) TRPM2 channel: A novel target for alleviating ischaemia‐reperfusion, chronic cerebral hypo‐perfusion and neonatal hypoxic‐ischaemic brain damage. Journal of Cellular and Molecular Medicine, 24 (1). pp. 4-12. ISSN 1582-1838

Jiang, L-H and Roger, S (2020) Targeting the P2X7 receptor in microglial cells to prevent brain inflammation. Neural Regeneration Research, 15 (7). pp. 1245-1246. ISSN 1673-5374

Milligan, CJ and Jiang, L-H (2019) Automated Planar Patch-Clamp Recording of P2X Receptors. Methods in Molecular Biology, 2041. pp. 285-300. ISSN 1064-3745

Jiang, L-H and Roger, S (2019) Heterologous Expression and Patch-Clamp Recording of P2X Receptors in HEK293 Cells. Purinergic Signaliing: Methods in Molecular Biology, 2041. pp. 261-273. ISSN 1064-3745

Yu, P, Liu, Z, Yu, X et al. (14 more authors) (2019) Direct Gating of the TRPM2 Channel by cADPR via Specific Interactions with the ADPR Binding Pocket. Cell Reports, 27 (12). 3684-3695.e4. ISSN 2211-1247

Malko, P, Mortadza, SAS, McWilliam, J et al. (1 more author) (2019) TRPM2 Channel in Microglia as a New Player in Neuroinflammation Associated With a Spectrum of Central Nervous System Pathologies. Frontiers in Pharmacology, 10. ARTN 239. ISSN 1663-9812

An, X, Fu, Z, Mai, C et al. (5 more authors) (2019) Increasing the TRPM2 Channel Expression in Human Neuroblastoma SH-SY5Y Cells Augments the Susceptibility to ROS-Induced Cell Death. Cells, 8 (1). ARTN 28. ISSN 2073-4409

Jiang, L-H, Li, X, Syed Mortadza, SA et al. (2 more authors) (2018) The TRPM2 channel nexus from oxidative damage to Alzheimer’s pathologies: An emerging novel intervention target for age-related dementia. Ageing Research Reviews, 47. pp. 67-79. ISSN 1568-1637

Wei, L, Syed Mortadza, SA and Jiang, L-H (2018) Melastatin-related transient receptor potential 2 channel in Aβ42-induced neuroinflammation: implications to Alzheimer's disease mechanism and development of therapeutics. Neural regeneration research, 13 (3). pp. 419-420. ISSN 1673-5374

Mortadza, SAS, Sim, JA, Neubrand, VE et al. (1 more author) (2018) A critical role of TRPM2 channel in Aβ₄₂‐induced microglial activation and generation of tumor necrosis factor‐α. Glia, 66 (3). pp. 562-575. ISSN 0894-1491

Jiang, Q, Gao, Y, Wang, C et al. (11 more authors) (2017) Nitration of TRPM2 as a Molecular Switch Induces Autophagy during Brain Pericyte Injury. Antioxid Redox Signal, 27 (16). pp. 1297-1316. ISSN 1523-0864

Li, X, Yang, W and Jiang, L-H (2017) Alteration in intracellular Zn2+ homeostasis as a result of TRPM2 channel activation contributes to ROS-induced hippocampal neuronal death. Frontiers in Molecular Neuroscience, 10. 414. ISSN 1662-5099

Jiang, L-H, Mousawi, F, Yang, X et al. (1 more author) (2017) ATP-induced Ca2+-signalling mechanisms in the regulation of mesenchymal stem cell migration. Cellular and Molecular Life Sciences, 74 (20). pp. 3697-3710. ISSN 1420-682X

Abuarab, N, Munsey, TS, Jiang, L-H et al. (2 more authors) (2017) High glucose–induced ROS activates TRPM2 to trigger lysosomal membrane permeabilization and Zn2+-mediated mitochondrial fission. Science Signaling, 10 (490). eaal4161. ISSN 1945-0877

Man, K, Jiang, L-H, Foster, R et al. (1 more author) (2017) Immunological Responses to Total Hip Arthroplasty. Journal of Functional Biomaterials, 8 (3). 33. ISSN 2079-4983

Barniol-Xicota, M, Kwak, S-H, Lee, S-D et al. (5 more authors) (2017) Escape from adamantane: Scaffold optimization of novel P2X7 antagonists featuring complex polycycles. Bioorganic & Medicinal Chemistry Letters, 27 (4). pp. 759-763. ISSN 0960-894X

Yu, P, Xue, X, Zhang, J et al. (8 more authors) (2017) Identification of the ADPR binding pocket in the NUDT9 homology domain of TRPM2. The Journal of General Physiology, 149 (2). pp. 219-235. ISSN 0022-1295

Peng, H, Hao, Y, Mousawi, F et al. (6 more authors) (2016) Purinergic and Store‐Operated Ca²⁺ Signaling Mechanisms in Mesenchymal Stem Cells and Their Roles in ATP‐Induced Stimulation of Cell Migration. Stem Cells, 34 (8). pp. 2102-2114. ISSN 1066-5099

Xu, F, Wu, X, Jiang, L-H et al. (2 more authors) (2016) An organelle K⁺ channel is required for osmoregulation in Chlamydomonas reinhardtii. Journal of Cell Science, 129 (15). pp. 3008-3014. ISSN 0021-9533

Wei, L, Caseley, E, Li, D et al. (1 more author) (2016) ATP-induced P2X Receptor-Dependent Large Pore Formation: How Much Do We Know? Frontiers in Pharmacology, 7. ARTN 5. ISSN 1663-9812

Roger, S, Jelassi, B, Couillin, I et al. (3 more authors) (2015) Understanding the roles of the P2X7 receptor in solid tumour progression and therapeutic perspectives. BBA: Biomembranes, 1848 (10, Pa). 2584 - 2602. ISSN 0005-2736

Caseley, EA, Muench, SP, Baldwin, SA et al. (3 more authors) (2015) Docking of competitive inhibitors to the P2X7 receptor family reveals key differences responsible for changes in response between rat and human. Bioorganic and Medicinal Chemistry Letters, 25 (16). 3164 - 3167. ISSN 0960-894X

Ye, M, Yang, W, Ainscough, JF et al. (11 more authors) (2014) TRPM2 channel deficiency prevents delayed cytosolic Zn²⁺ accumulation and CA1 pyramidal neuronal death after transient global ischemia. Cell Death and Disease, 5. e1541. ISSN 2041-4889

Yu, W, Jiang, L-H, Zheng, Y et al. (3 more authors) (2014) Inactivation of TRPM2 channels by extracellular divalent copper. PLoS ONE, 9 (11). e112071. ISSN 1932-6203

Zhang, Q-Y, Zhang, Y-Y, Xie, J et al. (8 more authors) (2014) Stiff substrates enhance cultured neuronal network activity. Scientific Reports, 4. 6215. ISSN 2045-2322

Caseley, EA, Muench, SP, Roger, S et al. (3 more authors) (2014) Non-synonymous single nucleotide polymorphisms in the P2X receptor genes: Association with diseases, impact on receptor functions and potential use as diagnosis biomarkers. International Journal of Molecular Sciences, 15 (8). 13344 - 13371. ISSN 1661-6596

Zou, J, Ainscough, JF, Yang, W et al. (6 more authors) (2013) A differential role of macrophage TRPM2 channels in Ca2+ signaling and cell death in early responses to H2O2. American Journal of Physiology: Cell Physiology, 305 (1). C61 - C69. ISSN 0363-6143

Jelassi, B, Anchelin, M, Chamouton, J et al. (6 more authors) (2013) Anthraquinone emodin inhibits human cancer cell invasiveness by antagonizing P2X7 receptors. Carcinogenesis, 34 (7). 1487 - 1496. ISSN 1460-2180

This list was generated on Mon Sep 28 01:17:56 2020 BST.