Translational potential of a mouse in vitro bioassay in predicting gastrointestinal adverse drug reactions in Phase I clinical trials.

Keating, C., Ewart, L., Grundy, L. et al. (2 more authors) (2014) Translational potential of a mouse in vitro bioassay in predicting gastrointestinal adverse drug reactions in Phase I clinical trials. Neurogastroenterology and Motility, 26 (7). 980 - 989.

Abstract

Metadata

Authors/Creators:
  • Keating, C.
  • Ewart, L.
  • Grundy, L.
  • Valentin, J.P.
  • Grundy, D.
Copyright, Publisher and Additional Information: © 2014 The Author(s). This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Keywords: adverse drug reaction; bioassay; biomarker; gastrointestinal motility; safety pharmacology
Dates:
  • Published: July 2014
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Science (Sheffield) > School of Biological Sciences (Sheffield) > Department of Biomedical Science (Sheffield)
Funding Information:
FunderGrant number
BBSRCBB/g01547/1
Depositing User: Symplectic Sheffield
Date Deposited: 16 Sep 2014 13:12
Last Modified: 16 Sep 2014 13:12
Published Version: http://dx.doi.org/10.1111/nmo.12349
Status: Published
Publisher: Wiley
Refereed: Yes
Identification Number: https://doi.org/10.1111/nmo.12349
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