Items where authors include "McDermott, MF"
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Magnotti, F, Chirita, D, Dalmon, S et al. (18 more authors) (2022) Steroid hormone catabolites activate the pyrin inflammasome through a non-canonical mechanism. Cell Reports, 41 (2). 111472. ISSN 2211-1247
Lara‐Reyna, S, Caseley, EA orcid.org/0000-0001-7591-143X, Topping, J et al. (4 more authors) (2022) Inflammasome activation: from molecular mechanisms to autoinflammation. Clinical & Translational Immunology, 11 (7). e1404. ISSN 2050-0068
Caseley, EA orcid.org/0000-0001-7591-143X, Lara-Reyna, S, Poulter, JA orcid.org/0000-0003-2048-5693 et al. (6 more authors) (2022) An Atypical Autoinflammatory Disease Due to an LRR Domain NLRP3 Mutation Enhancing Binding to NEK7. Journal of Clinical Immunology, 42 (1). pp. 158-170. ISSN 0271-9142
Holbrook, JA, Jarosz-Griffiths, HH, Caseley, E et al. (5 more authors) (2021) Neurodegenerative Disease and the NLRP3 Inflammasome. Frontiers in Pharmacology, 12. 643254. ISSN 1663-9812
Lara-Reyna, S, Poulter, JA orcid.org/0000-0003-2048-5693, Vasconcelos, EJR orcid.org/0000-0001-5130-6622 et al. (5 more authors) (2021) Identification of Critical Transcriptomic Signaling Pathways in Patients with H Syndrome and Rosai-Dorfman Disease. Journal of Clinical Immunology, 41 (2). pp. 441-457. ISSN 0271-9142
Lara-Reyna, S, Holbrook, J orcid.org/0000-0001-8660-0282, Jarosz-Griffiths, HH orcid.org/0000-0001-5154-4815 et al. (2 more authors) (2020) Dysregulated signalling pathways in innate immune cells with cystic fibrosis mutations. Cellular and Molecular Life Sciences, 77 (22). pp. 4485-4503. ISSN 1420-682X
Peckham, D orcid.org/0000-0001-7723-1868, McDermott, MF orcid.org/0000-0002-1015-0745, Savic, S orcid.org/0000-0001-7910-0554 et al. (1 more author) (2020) COVID-19 meets Cystic Fibrosis: for better or worse? Genes & Immunity, 21 (4). pp. 260-262. ISSN 1466-4879
Caseley, EA orcid.org/0000-0001-7591-143X, Poulter, JA orcid.org/0000-0003-2048-5693, Rodrigues, F et al. (1 more author) (2020) Inflammasome inhibition under physiological and pharmacological conditions. Genes & Immunity, 21 (4). pp. 211-223. ISSN 1466-4879
Savic, S orcid.org/0000-0001-7910-0554, Caseley, EA orcid.org/0000-0001-7591-143X and McDermott, MF orcid.org/0000-0002-1015-0745 (2020) Moving towards a systems-based classification of innate immune-mediated diseases. Nature Reviews Rheumatology, 16 (4). pp. 222-237. ISSN 1759-4790
Jarosz-Griffiths, HH orcid.org/0000-0001-5154-4815, Scambler, T, Wong, CH orcid.org/0000-0003-2108-1615 et al. (11 more authors) (2020) Different CFTR modulator combinations downregulate inflammation differently in cystic fibrosis. eLife, 9. e54556. ISSN 2050-084X
Standing, ASI, Hong, Y, Paisan-Ruiz, C et al. (11 more authors) (2020) TRAP1 chaperone protein mutations and autoinflammation. Life Science Alliance, 3 (2). e201900376. ISSN 2575-1077
Jarosz-Griffiths, HH orcid.org/0000-0001-5154-4815, Holbrook, J, Lara-Reyna, S et al. (1 more author) (2019) TNF receptor signalling in autoinflammatory diseases. International Immunology, 31 (10). pp. 369-348. ISSN 0953-8178
Scambler, T orcid.org/0000-0003-2468-0218, Jarosz-Griffiths, HH orcid.org/0000-0001-5154-4815, Lara-Reyna, S et al. (7 more authors) (2019) ENaC-mediated sodium influx exacerbates NLRP3-dependent inflammation in Cystic Fibrosis. eLife, 8. e49248. ISSN 2050-084X
Scambler, T, Jarosz-Griffiths, HH orcid.org/0000-0001-5154-4815, Lara-Reyna, S et al. (7 more authors) (2019) Excessive ENaC-mediated sodium influx drives NLRP3 inflammasome-dependent autoinflammation in cystic fibrosis. eLife, 8. e49248. ISSN 2050-084X
Lara-Reyna, S, Scambler, T, Holbrook, J et al. (6 more authors) (2019) Metabolic Reprograming of Cystic Fibrosis Macrophages via the IRE1α Arm of the Unfolded Protein Response Results in Exacerbated Inflammation. Frontiers in Immunology, 10. 1789. ISSN 1664-3224
Scambler, T, Holbrook, J, Savic, S orcid.org/0000-0001-7910-0554 et al. (2 more authors) (2018) Autoinflammatory disease in the lung. Immunology, 154 (4). pp. 563-573. ISSN 0019-2805
Rahmati, M, Moosavi, MA and McDermott, MF orcid.org/0000-0002-1015-0745 (2018) ER Stress: A Therapeutic Target in Rheumatoid Arthritis? Trends in Pharmacological Sciences, 39 (7). pp. 610-623. ISSN 0165-6147
Gillespie, J, Ross, RL, Corinaldesi, C et al. (7 more authors) (2018) Transforming Growth Factor β Activation Primes Canonical Wnt Signaling Through Down-Regulation of Axin-2. Arthritis & Rheumatology, 70 (6). pp. 932-942. ISSN 2326-5191
Lara-Reyna, S, Scambler, T, Holbrook, J et al. (3 more authors) (2018) Regulation of the Unfolded Protein Response in Disease: Cellular Stress and microRNAs. Current Immunology Reviews, 14 (1). pp. 3-14. ISSN 1573-3955
Harrison, SR, Scambler, T, Oubussad, L et al. (4 more authors) (2018) Inositol-Requiring Enzyme 1-Mediated Downregulation of MicroRNA (miR)-146a and miR-155 in Primary Dermal Fibroblasts across Three TNFRSF1A Mutations Results in Hyperresponsiveness to Lipopolysaccharide. Frontiers in Immunology, 9. 173. ISSN 1664-3224
Cope, AP, Barnes, MR, Belson, A et al. (33 more authors) (2018) Erratum: The RA-MAP Consortium: a working model for academia–industry collaboration. Nature Reviews Rheumatology, 14 (2). p. 119. ISSN 1759-4790
Cope, AP, Barnes, MR, Belson, A et al. (33 more authors) (2018) The RA-MAP Consortium: A working model for academia-industry collaboration. Nature Reviews Rheumatology, 14 (1). pp. 53-60. ISSN 1759-4790
Ouboussad, L, Hunt, L, Hensor, EMA orcid.org/0000-0002-5245-4755 et al. (5 more authors) (2017) Profiling microRNAs in individuals at risk of progression to rheumatoid arthritis. Arthritis Research and Therapy, 19. 288. ISSN 1478-6354
West, C and McDermott, MF (2017) Effects of microRNA-146a on the proliferation and apoptosis of human osteochondrocytes by targeting TRAF6 through the NF- κB signalling pathway. Bioscience Reports, 37 (4). BSR20170180. ISSN 0144-8463
Aksentijevich, I and McDermott, MF orcid.org/0000-0002-1015-0745 (2017) Lessons from characterization and treatment of the inflammatory syndromes. Current Opinion in Rheumatology, 29 (2). pp. 187-194. ISSN 1040-8711
Ianitti, T, McDermott, MF orcid.org/0000-0002-1015-0745, Laurino, C et al. (2 more authors) (2017) Corticosteroid transdermal delivery significantly improves arthritis pain and functional disability. Drug Delivery and Translational Research, 7 (1). pp. 156-161. ISSN 2190-393X
Pathak, S, McDermott, MF orcid.org/0000-0002-1015-0745 and Savic, S orcid.org/0000-0001-7910-0554 (2017) Autoinflammatory diseases: Update on classification diagnosis and management. Journal of Clinical Pathology, 70 (1). pp. 1-8. ISSN 0021-9746
Peckham, D orcid.org/0000-0001-7723-1868, Scambler, T, Savic, S orcid.org/0000-0001-7910-0554 et al. (1 more author) (2017) The burgeoning field of innate immune-mediated disease and autoinflammation. Journal of Pathology, 241 (2). pp. 123-139. ISSN 0022-3417
Scambler, T, Feeley, C and McDermott, MF orcid.org/0000-0002-1015-0745 (2016) Protection against lupus-like inflammatory disease is in the LAP of non-canonical autophagy. Annals of Translational Medicine, 4 (24). 513. p. 513. ISSN 2305-5839
Harrison, SR, McGonagle, D, Nizam, S et al. (4 more authors) (2016) Anakinra as a diagnostic challenge and treatment option for systemic autoinflammatory disorders of undefined etiology. JCI Insight, 1 (6). e86336. ISSN 2379-3708
Agyemang, A, Harrison, SR, Siegel, RM et al. (1 more author) (2015) Protein misfolding and dysregulated protein homeostasis in autoinflammatory diseases and beyond. Seminars in Immunopathology, 37 (4). pp. 335-347. ISSN 1863-2297
Sedger, LM and McDermott, MF (2014) TNF and TNF-receptors: From mediators of cell death and inflammation to therapeutic giants - past, present and future. Cytokine and Growth Factor Reviews, 25 (4). 453 - 472. ISSN 1359-6101
Mathews, RJ, Robinson, JI orcid.org/0000-0001-5425-7520, Battellino, M et al. (17 more authors) (2014) Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment. Annals of the Rheumatic Diseases, 73 (6). pp. 1202-1210. ISSN 0003-4967
Savic, S orcid.org/0000-0001-7910-0554, Ouboussad, L, Dickie, LJ et al. (10 more authors) (2014) TLR dependent XBP-1 activation induces an autocrine loop in rheumatoid arthritis synoviocytes. Journal of Autoimmunity, 50. pp. 59-66. ISSN 0896-8411
Doble, R, McDermott, MF, Cesur, O et al. (2 more authors) (2014) IL-17A RNA aptamer: possible therapeutic potential in some cells, more than we bargained for in others? Journal of Investigative Dermatology, 134 (3). 852 - 855. ISSN 0022-202X
Lucherini, OM, Obici, L, Ferracin, M et al. (11 more authors) (2013) First Report of Circulating MicroRNAs in Tumour Necrosis Factor Receptor-Associated Periodic Syndrome (TRAPS). PLoS ONE, 8 (9). e73443. ISSN 1932-6203
Galeazzi, M, Obici, L, Ferracin, M et al. (10 more authors) (2013) OP0074 First Report of Circulating Micrornas in Tumour Necrosis Factor Receptor-Associated Periodic Syndrome (TRAPS). Annals of the Rheumatic Diseases, 72 (Suppl 3). p. 75. ISSN 0003-4967
Rittore, C, Sanchez, E, Soler, S et al. (6 more authors) (2013) Identification of a new exon 2-skipped TNFR1 transcript: Regulation by three functional polymorphisms of the TNFR-associated periodic syndrome (TRAPS) gene. Annals of the Rheumatic Diseases, 73 (1). 290 - 297. ISSN 0003-4967
McDermott, MF (2013) The spectrum of NLR and related molecules in human disease. Annals of the Rheumatic Diseases, 72 (3). 13 - 13. ISSN 0003-4967
Gillespie, J, Mathews, R and McDermott, MF orcid.org/0000-0002-1015-0745 (2010) Rilonacept in the management of cryopyrin-associated periodic syndromes (CAPS). Journal of Inflammation Research, 3. pp. 1-8. ISSN 1178-7031
Dickie, LJ, Savic, S orcid.org/0000-0001-7910-0554, Aziz, A et al. (2 more authors) (2010) Periodic fever syndrome and autoinflammatory diseases. F1000 Faculty Reviews, 2 (3). ISSN 1757-5931
Church, LD, Savic, S orcid.org/0000-0001-7910-0554 and McDermott, MF orcid.org/0000-0002-1015-0745 (2008) Long term management of patients with cryopyrin-associated periodic syndromes (CAPS): Focus on rilonacept (IL-1 Trap). Biologics: Targets and Therapy, 2 (4). pp. 733-742. ISSN 1177-5475
Mathews, RJ, Sprakes, MB and McDermott, MF orcid.org/0000-0002-1015-0745 (2008) NOD-like receptors and inflammation. Arthritis Research and Therapy, 10 (6). 228. ISSN 1478-6354
Proceedings Paper
Jarosz-Griffiths, H orcid.org/0000-0001-5154-4815, Scambler, T, Lara Reyna, S orcid.org/0000-0002-9986-5279 et al. (7 more authors) (2019) ePS1.09 Inhibition of autoinflammation in cystic fibrosis using small molecule therapy. In: Journal of Cystic Fibrosis. 42nd European Cystic Fibrosis Conference, 05-08 Jun 2019, Liverpool, UK. Elsevier , S41.
Jarosz-Griffiths, H orcid.org/0000-0001-5154-4815, Scambler, T, Holbrook, J et al. (5 more authors) (2018) S138 Inhibition of auto-inflammation in cystic fibrosis using small molecule therapy. In: Thorax. Winter Meeting of the British-Thoracic-Society, 05-07 Dec 2018, Westminster, England. BMJ Publishing Group , A86-A86.
Scambler, T, Wong, C, Pathak, S et al. (7 more authors) (2018) Enac modulates innate immune inflammation and metabolism in cystic fibrosis. In: Pediatric Pulmonology. 32nd Annual North American Cystic Fibrosis Conference, 18-20 Oct 2018, Denver, CO, USA. Wiley , pp. 184-185.
Lara Reyna, S orcid.org/0000-0002-9986-5279, Scambler, T, Holbrook, J et al. (6 more authors) (2018) Overactivation of IRE1α drives overexpression of IL-6 in cystic fibrosis. In: Pediatric Pulmonology. 32nd Annual North American Cystic Fibrosis Conference, 18-20 Oct 2018, Denver, CO, USA. Wiley , p. 189.
Holbrook, J, Scambler, T, Lara Reyna, S orcid.org/0000-0002-9986-5279 et al. (5 more authors) (2018) The effect of cysteamine and epigallocatechin gallate on the inflammatory phenotype in cystic fibrosis. In: Pediatric Pulmonology. 32nd Annual North American Cystic Fibrosis Conference, 18-20 Oct 2018, Denver, CO, USA. Wiley , p. 245.
Scambler, T orcid.org/0000-0003-2468-0218, Wong, C, Pathak, S et al. (7 more authors) (2018) WS04.3 Sodium influx modulates innate immune inflammation and metabolism in cystic fibrosis. In: Journal of Cystic Fibrosis. 41st European Cystic Fibrosis Conference, 06-09 Jun 2018, Belgrade, Serbia. Elsevier BV , S8-S8.
Ouboussad, L, Wong, C, Hunt, L et al. (4 more authors) (2017) Effect of tocilizumab therapy on il-6 signalling pathway in early rheumatoid arthritis patients. In: Annals of the Rheumatic Diseases. EWRR, 02-04 Mar 2017, Athens. BMJ Publishing Group , A40-A40.
Ouboussad, L, Wong, C, Hunt, L et al. (3 more authors) (2016) A2.40 Investigating IL-6 pathway signalling kinetics in peripheral blood single cell subsets with tocilizumab therapy in patients with early rheumatoid arthritis. In: Annals of the Rheumatic Diseases. 36th European Workshop for Rheumatology Research, 25-27 Feb 2016, York, UK. BMJ Publishing Group , A31-A31.