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Number of items: 46.

Article

Billings, C.G., Lewis, R., Hurdman, J.A. et al. (12 more authors) (2019) Express: The incremental shuttle walk test predicts mortality in non-group 1 pulmonary hypertension: results from the ASPIRE Registry. Pulmonary Circulation. ISSN 2045-8932

Sofianopoulou, E., Kaptoge, S., Gräf, S. et al. (30 more authors) (2019) Traffic exposures, air pollution and outcomes in pulmonary arterial hypertension: A United Kingdom cohort study analysis. European Respiratory Journal. ISSN 0903-1936

Rhodes, C.J., Batai, K., Bleda, M. et al. (118 more authors) (2019) Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis. Lancet Respiratory Medicine, 7 (3). pp. 227-238. ISSN 2213-2600

Sweatt, A.J., Hedlin, H.K., Balasubramanian, V. et al. (11 more authors) (2019) Discovery of distinct immune phenotypes using machine learning in pulmonary arterial hypertension. Circulation Research. ISSN 0009-7330

Bergemann, R., Allsopp, J., Jenner, H. et al. (8 more authors) (2018) High levels of healthcare utilization prior to diagnosis in idiopathic pulmonary arterial hypertension support the feasibility of an early diagnosis algorithm: the SPHInX project. Pulmonary Circulation, 8 (4). pp. 1-9. ISSN 2045-8940

Bohnen, M.S., Ma, L., Zhu, N. et al. (47 more authors) (2018) Loss-of-function ABCC8 mutations in pulmonary arterial hypertension. Circulation: Genomic and Precision Medicine, 11 (10). e002087. ISSN 2574-8300

Quadery, S.R., Swift, A.J., Billings, C. et al. (23 more authors) (2018) The impact of patient choice on survival in chronic thromboembolic pulmonary hypertension. European Respiratory Journal , 52 (3). 1800589. ISSN 0903-1936

Farkas, D., Thompson, A.A.R. orcid.org/0000-0002-0717-4551, Bhagwani, A.R. et al. (14 more authors) (2018) Toll-like receptor 3 is a therapeutic target for pulmonary hypertension. American Journal of Respiratory and Critical Care Medicine. ISSN 1073-449X

Ramakrishnan, L., Pedersen, S.L., Toe, Q.K. et al. (8 more authors) (2018) The Hepcidin/Ferroportin axis modulates proliferation of pulmonary artery smooth muscle cells. Scientific Reports, 8. 12972. ISSN 2045-2322

Braithwaite, A.T. orcid.org/0000-0003-3228-2172, Marriott, H. and Lawrie, A. (2018) Divergent Roles for TRAIL in Lung Diseases. Frontiers in Medicine, 5. 212. ISSN 2296-858X

Billings, C.G., Lewis, R., Armstrong, I.J. et al. (10 more authors) (2018) Incremental Shuttle Walking Test Distance Is Reduced in Patients With Pulmonary Hypertension in World Health Organisation Functional Class I. Frontiers in Medicine, 5. 172. ISSN 2296-858X

Hickey, P.M. orcid.org/0000-0002-4683-7696, Lawrie, A. orcid.org/0000-0003-4192-9505 and Condliffe, R. (2018) Circulating protein biomarkers in systemic sclerosis related pulmonary arterial hypertension: a review of published data. Frontiers in Medicine, 5. 175. ISSN 2296-858X

Graf, S., Haimel, M., Bleda, M. et al. (62 more authors) (2018) Identification of rare sequence variation underlying heritable pulmonary arterial hypertension. Nature Communications, 9. 1416. ISSN 2041-1723

Boehm, M., Arnold, N., Braithwaite, A. et al. (11 more authors) (2018) Eplerenone attenuates pathological pulmonary vascular rather than right ventricular remodeling in pulmonary arterial hypertension. BMC Pulmonary Medicine, 18. 41.

Chen, K.-H., Dasgupta, A., Lin, J. et al. (13 more authors) (2018) Epigenetic Dysregulation of the Drp1 Binding Partners MiD49 and MiD51 Increases Mitotic Mitochondrial Fission and Promotes Pulmonary Arterial Hypertension: Mechanistic and Therapeutic Implications. Circulation, 117. 031258. ISSN 0009-7322

Renshall, L.J., Arnold, N.D. orcid.org/0000-0002-4317-5738, West, L. et al. (10 more authors) (2017) EXPRESS: Selective Improvement of Pulmonary Arterial Hypertension with a Dual ETA/ETB Receptors Antagonist in the Apolipoprotein E-/- Model of PAH and Atherosclerosis. Pulmonary Circulation . ISSN 2045-8932

Renshall, L., Arnold, N., West, L. et al. (11 more authors) (2017) Selective improvement of pulmonary arterial hypertension with dual ETA/ETB receptors antagonist in the apolipoprotein E-/- model of PAH and atherosclerosis. Pulmonary Circulation, 8 (1). ISSN 2045-8940

Zhang, H.-D., Lv, Z.-C., Wang, L.-T. et al. (7 more authors) (2017) Prognostic Significance of Reduced Blood Pressure Response to Exercise in Pediatric Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine, 196 (11). ISSN 1073-449X

Hadinnapola, C., Bleda, M., Haimel, M. et al. (41 more authors) (2017) Phenotypic Characterisation of EIF2AK4 Mutation Carriers in a Large Cohort of Patients Diagnosed Clinically with Pulmonary Arterial Hypertension. Circulation, 136 (15). ISSN 0009-7322

Pickworth, J.A. orcid.org/0000-0002-7199-364X, Rothman, A., Iremonger, J. et al. (9 more authors) (2017) EXPRESS: Differential IL-1 signalling induced by BMPR2 deficiency drives pulmonary vascular remodelling. Pulmonary Circulation . ISSN 2045-8932

Swift, A.J., Capener, D., Johns, C. orcid.org/0000-0003-3724-0430 et al. (10 more authors) (2017) Magnetic Resonance Imaging in the Prognostic Evaluation of Patients with Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine, 196 (2). ISSN 1073-449X

Rhodes, C.J., Wharton, J., Ghataorhe, P. et al. (16 more authors) (2017) Plasma proteome analysis in patients with pulmonary arterial hypertension: an observational cohort study. The Lancet Respiratory Medicine. ISSN 2213-2600

Billings, C.G., Hurdman, J.A., Condliffe, R.A. et al. (13 more authors) (2017) Incremental Shuttle Walking Test Distance and Autonomic Dysfunction Predict Survival in Pulmonary Arterial Hypertension. The Journal of Heart and Lung Transplantation. ISSN 1053-2498

Thompson, A.A.R. orcid.org/0000-0002-0717-4551, Dickinson, R.S., Murphy, F. et al. (32 more authors) (2017) Hypoxia determines survival outcomes of bacterial infection through HIF-1α-dependent reprogramming of leukocyte metabolism. Science Immunology, 2 (8). ISSN 2470-9468

Rhodes, C.J., Ghataorhe, P., Wharton, J. et al. (18 more authors) (2017) Plasma Metabolomics Implicate Modified Transfer RNAs and Altered Bioenergetics in the Outcome of Pulmonary Arterial Hypertension. Circulation, 135 (5). pp. 460-475. ISSN 0009-7322

Dawson, S. and Lawrie, A. orcid.org/0000-0003-4192-9505 (2017) From bones to blood pressure, developing novel biologic approaches targeting the osteoprotegein pathway for pulmonary vascular disease. Pharmacol Ther, 169. pp. 78-82.

Thompson, A.A.R. orcid.org/0000-0002-0717-4551 and Lawrie, A. orcid.org/0000-0003-4192-9505 (2017) Targeting Vascular Remodeling to Treat Pulmonary Arterial Hypertension. Trends in Molecular Medicine, 23 (1). pp. 31-45. ISSN 1471-4914

Boehm, M., Lawrie, A. orcid.org/0000-0003-4192-9505, Wilhelm, J. et al. (6 more authors) (2016) Maintained right ventricular pressure overload induces ventricular-arterial decoupling in mice. Experimental Physiology. ISSN 0958-0670

Rothman, A.M., Rowlands, D.J. and Lawrie, A. orcid.org/0000-0003-4192-9505 (2016) miRNA-140-5p: new avenue for pulmonary arterial hypertension drug development? Epigenomics. ISSN 1750-1911

Rothman, A.M. orcid.org/0000-0002-7847-4500, Arnold, N., Pickworth, J. et al. (10 more authors) (2016) MicroRNA-140-5p and SMURF1 Regulate Pulmonary Arterial Hypertension. Journal of Clinical Investigation, 126 (7). pp. 2495-2508. ISSN 1558-8238

Rothman, A., Arnold, N., Pickworth, J. et al. (9 more authors) (2016) MicroRNA-140-5p and SMURF1 regulate pulmonary arterial hypertension. Clinical Investigation. ISSN 2041-6792

Luong, L., Duckles, H., Schenkel, T. et al. (20 more authors) (2016) Heart rate reduction with ivabradine promotes shear stress-dependent anti-inflammatory mechanisms in arteries. Thrombosis and Haemostasis, 116 (1). pp. 181-190. ISSN 0340-6245

Rothman, A.M.K. orcid.org/0000-0002-7847-4500, Arnold, N.D., Chang, W. et al. (8 more authors) (2015) Pulmonary Artery Denervation Reduces Pulmonary Artery Pressure and Induces Histological Changes in an Acute Porcine Model of Pulmonary Hypertension. CIRCULATION-CARDIOVASCULAR INTERVENTIONS, 8. e002569. ISSN 1941-7640

Spiekerkoetter, E., Sung, Y.K., Sudheendra, D. et al. (11 more authors) (2015) Low-Dose FK506 (Tacrolimus) in End-Stage Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine, 192 (2). 254 - 257. ISSN 1073-449X

McCullagh, B.N., Costello, C.M., Li, L. et al. (9 more authors) (2015) Elevated plasma CXCL12 alpha is associated with a poorer prognosis in pulmonary arterial hypertension. PLoS ONE, 10 (4). e0123709. ISSN 1932-6203

Pérez de Ciriza, C., Lawrie, A. and Varo, N. (2015) Osteoprotegerin in cardiometabolic disorders. International Journal of Endocrinology and Metabolism, 2015. 564934. ISSN 1726-9148

Dawson, S., Arnold, N., Pickworth, J. et al. (2 more authors) (2014) TRAIL Deficient Mice Are Protected from Sugen/Hypoxia Induced Pulmonary Arterial Hypertension. Diseases, 2 (3). pp. 260-273. ISSN 2079-9721

Watson, O., Novodvorsky, P., Gray, C. et al. (8 more authors) (2013) Blood flow suppresses vascular Notch signalling via dll4 and is required for angiogenesis in response to hypoxic signalling. Cardiovascular Research, 100 (2). 252 - 261. ISSN 0008-6363

Hameed, A., Bennett, E., Ciani, B. et al. (5 more authors) (2013) No evidence for cardiac dysfunction in Kif6 mutant mice. PLoS One, 8 (1). ISSN 1932-6203

Hameed, A.G., Arnold, N.D., Chamberlain, J. et al. (12 more authors) (2012) Inhibition of tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) reverses experimental pulmonary hypertension. The Journal of Experimental Medicine, 209 (11). 1919 - 1935. ISSN 0022-1007

McGrath, E.E., Lawrie, A., Marriott, H.M. et al. (11 more authors) (2012) Deficiency of tumour necrosis factor-related apoptosis-inducing ligand exacerbates lung injury and fibrosis. Thorax, 67 (9). 796 - 803. ISSN 0040-6376

Condliffe, R., Pickworth, J. orcid.org/0000-0002-7199-364X, Hopkinson, K. et al. (14 more authors) (2012) Serum osteoprotegerin is increased and predicts survival in idiopathic pulmonary arterial hypertension. Pulmonary circulation, 2 (1). pp. 21-27. ISSN 2045-8932

Lawrie, A., Hameed, A.G., Chamberlain, J. et al. (7 more authors) (2011) Paigen diet-fed apolipoprotein E knockout mice develop severe pulmonary hypertension in an interleukin-1-dependent manner. American Journal of Pathology, 179 (4). pp. 1693-1705. ISSN 0002-9440

McGrath, E. E., Marriott, H. M., Lawrie, A. et al. (5 more authors) (2011) TNF-related apoptosis-inducing ligand (TRAIL) regulates inflammatory neutrophil apoptosis and enhances resolution of inflammation. Journal of Leukocyte Biology, 90 (5). pp. 855-65. ISSN 1938-3673

Proceedings Paper

Swift, A.J., Lu, H. orcid.org/0000-0002-0349-2181, Garg, P. orcid.org/0000-0002-5483-169X et al. (8 more authors) (2019) 543 A machine-learning CMR approach to extract disease features and automate pulmonary arterial hypertension diagnosis. In: European Heart Journal - Cardiovascular Imaging. EuroCMR 2019, 02-04 May 2019, Venice, Italy. Oxford University Press (OUP) .

Rothman, A.M. orcid.org/0000-0002-7847-4500, Arnold, N., Abou Hanna, J. et al. (11 more authors) (2017) Feasibility and safety of a wireless pulmonary artery pressure monitoring system in chronic porcine models of pulmonary hypertension. In: European Heart Journal Supplements. ESC Congress 2017, 26-30 Aug 2017, Barcelona, Spain. Oxford University Press (OUP) .

This list was generated on Mon Aug 19 03:26:27 2019 BST.