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Article

Vazquez-Villaseñor, I., Garwood, C.J., Heath, P.R. et al. (3 more authors) (2019) Expression of p16 and p21 in the frontal association cortex of ALS/MND brains suggest neuronal cell cycle dysregulation and astrocyte senescence in early stages of the disease. Neuropathology and Applied Neurobiology. ISSN 0305-1846

Mozumder, M., Pozo, J.M., Coelho, S. et al. (5 more authors) (2019) Quantitative histomorphometry of capillary microstructure in deep white matter. NeuroImage: Clinical, 23. 101839. ISSN 2213-1582

Coelho, S., Pozo, J.M., Costantini, M. et al. (5 more authors) (2019) Histological data of axons, astrocytes, and myelin in deep subcortical white matter populations. Data in Brief, 23. 103762. ISSN 2352-3409

Wharton, S.B., Verber, N.S., Wagner, B.E. et al. (6 more authors) (2019) Combined FUS+ basophilic inclusion body disease and atypical tauopathy presenting with an ALS/MND-plus phenotype. Neuropathology and Applied Neurobiology. ISSN 0305-1846

Waller, R. orcid.org/0000-0001-5815-8829, Baxter, L., Fillingham, D.J. et al. (7 more authors) (2019) Iba-1-/CD68+ microglia are a prominent feature of age-associated deep subcortical white matter lesions. PLoS One, 14 (1). e0210888. ISSN 1932-6203

Ratcliffe, L.E., Vázquez Villaseñor, I., Jennings, L. et al. (8 more authors) (2018) Loss of IGF1R in human astrocytes alters complex I activity and support for neurons. Neuroscience, 390. pp. 46-59. ISSN 0306-4522

Coelho, S. orcid.org/0000-0002-1039-4803, Pozo, J.M., Costantini, M. et al. (5 more authors) (2018) Local volume fraction distributions of axons, astrocytes, and myelin in deep subcortical white matter. NeuroImage, 179. pp. 275-287. ISSN 1053-8119

Morgan, S.V., Garwood, C.J., Jennings, L. et al. (10 more authors) (2018) Proteomic and cellular localisation studies suggest non-tight junction cytoplasmic and nuclear roles for occludin in astrocytes. European Journal of Neuroscience. ISSN 0953-816X

Cooper-Knock, J. orcid.org/0000-0002-0873-8689, Robins, H., Niedermoser, I. et al. (11 more authors) (2017) Targeted Genetic Screen in Amyotrophic Lateral Sclerosis Reveals Novel Genetic Variants with Synergistic Effect on Clinical Phenotype. Frontiers in Molecular Neuroscience , 10. 370. ISSN 1662-5099

Fahrenhold, M., Rakic, S., Classey, J. et al. (4 more authors) (2017) TREM2 expression in the human brain: a marker of monocyte recruitment? Brain Pathology. ISSN 1015-6305

Ince, P.G., Minett, T., Forster, G. et al. (3 more authors) (2017) Microinfarcts in an older population-representative brain donor cohort (MRC CFAS): Prevalence, relation to dementia and mobility, and implications for the evaluation of cerebral Small Vessel Disease. Neuropathology and Applied Neurobiology, 43 (5). pp. 409-418. ISSN 0305-1846

Garwood, C.J., Ratcliffe, L.E., Simpson, J.E. et al. (3 more authors) (2017) Review: Astrocytes in Alzheimer's disease and other age-associated dementias: a supporting player with a central role. Neuropathology and Applied Neurobiology, 43 (4). pp. 281-298. ISSN 1365-2990

Davis, D.H.J., Muniz-Terrera, G., Keage, H.A.D. et al. (21 more authors) (2017) Association of delirium with cognitive decline in late life: A neuropathologic study of 3 population-based cohort studies. JAMA Psychiatry, 74 (3). pp. 244-251. ISSN 2168-622X

Waller, R., Woodroofe, M.N., Wharton, S.B. et al. (8 more authors) (2016) Gene expression profiling of the astrocyte transcriptome in multiple sclerosis normal appearing white matter reveals a neuroprotective role. Journal of Neuroimmunology, 299. pp. 139-146. ISSN 1872-8421

Garwood, C.J., Ratcliffe, L.E., Simpson, J.E. et al. (3 more authors) (2016) Review: Astrocytes in Alzheimer's disease and other age-associated dementias; a supporting player with a central role. Neuropathology and Applied Neurobiology. ISSN 0305-1846

Taga, M., Minett, T., Classey, J. et al. (6 more authors) (2016) Metaflammasome components in the human brain: a role in dementia with alzheimer's pathology? Brain Pathology. ISSN 1015-6305

Minett, T., Classey, J., Matthews, F.E. et al. (7 more authors) (2016) Microglial immunophenotype in dementia with Alzheimer's pathology. Journal of Neuroinflammation, 13. ARTN 135. ISSN 1742-2094

Heath, P.R., Appleby-Mallinder, C., Wyles, M.D. et al. (3 more authors) (2016) Expression microdissection isolation of enriched cell populations from archival brain tissue. Journal of Neuroscience Methods. ISSN 0165-0270

Matthews, F.E., Stephan, B.C.M., Robinson, L. et al. (22 more authors) (2016) A two decade dementia incidence comparison from the Cognitive Function and Ageing Studies I and II. Nature Communications, 7. 11398. p. 11398. ISSN 2041-1723

Bury, J.J., Highley, J.R., Cooper-Knock, J. et al. (6 more authors) (2016) Oligogenic inheritance of optineurin (OPTN) and C9ORF72 mutations in ALS highlights localisation of OPTN in the TDP-43-negative inclusions of C9ORF72-ALS. Neuropathology , 36 (2). pp. 125-134. ISSN 0919-6544

Wharton, S.B., Minett, T., Drew, D. et al. (5 more authors) (2016) Epidemiological pathology of Tau in the ageing brain: application of staging for neuropil threads (BrainNet Europe protocol) to the MRC cognitive function and ageing brain study. Acta Neuropathol Communications, 4. 11. ISSN 2051-5960

Sivadasan, R., Hornburg, D., Drepper, C. et al. (11 more authors) (2016) C9ORF72 interaction with cofilin modulates actin dynamics in motor neurons. Nature Neuroscience, 19. pp. 1610-1618. ISSN 1097-6256

Fluteau, A., Ince, P.G., Minett, T. et al. (10 more authors) (2015) The nuclear retention of transcription factor FOXO3a correlates with a DNA damage response and increased glutamine synthetase expression by astrocytes suggesting a neuroprotective role in the ageing brain. Neuroscience Letters, 609. pp. 11-17. ISSN 0304-3940

Peuralinna, T., Myllykangas, L., Oinas, M. et al. (14 more authors) (2015) Genome-wide association study of neocortical Lewy-related pathology. Annals of Clinical and Translational Neurology, 2 (9). pp. 920-931.

Al-Mashhadi, S., Simpson, J.E., Heath, P.R. et al. (6 more authors) (2015) Oxidative Glial Cell Damage Associated with White Matter Lesions in the Aging Human Brain. Brain Pathology, 25 (5). pp. 565-574. ISSN 1015-6305

Garwood, C.J., Ratcliffe, L.E., Morgan, S.V. et al. (7 more authors) (2015) Insulin and IGF1 signalling pathways in human astrocytes in vitro and in vivo; characterisation, subcellular localisation and modulation of the receptors. Molecular Brain, 8. 51 . ISSN 1756-6606

Simpson, J.E., Ince, P.G., Minett, T. et al. (9 more authors) (2015) Neuronal DNA damage response-associated dysregulation of signalling pathways and cholesterol metabolism at the earliest stages of Alzheimer-type pathology. Neuropathology and Applied Neurobiology. ISSN 0305-1846

Cooper-Knock, J., Higginbottom, A., Stopford, M.J. et al. (7 more authors) (2015) Antisense RNA foci in the motor neurons of C9ORF72-ALS patients are associated with TDP-43 proteinopathy. Acta Neuropathologica, 130 (1). pp. 63-75. ISSN 0001-6322

Highley, J.R., Lorente Pons, A., Cooper-Knock, J. et al. (5 more authors) (2015) Motor neurone disease/amyotrophic lateral sclerosis associated with intermediate length CAG repeat expansions in Ataxin-2 does not have 1C2-positive polyglutamine inclusions. Neuropathology and Applied Neurobiology. ISSN 0305-1846

Simpson, J.E., Ince, P.G., Matthews, F.E. et al. (7 more authors) (2015) A neuronal DNA damage response is detected at the earliest stages of Alzheimer's neuropathology and correlates with cognitive impairment in the Medical Research Council's Cognitive Function and Ageing Study ageing brain cohort. Neuropathology and Applied Neurobiology, 41 (4). pp. 483-496. ISSN 0305-1846

Zaccai, J., Brayne, C., Matthews, F.E. et al. (2 more authors) (2015) Alpha-synucleinopathy and neuropsychological symptoms in a population-based cohort of the elderly. Alzheimer's Research & Therapy, 7. ARTN 19. ISSN 1758-9193

Mathur, R., Ince, P.G., Minett, T. et al. (7 more authors) (2015) A Reduced Astrocyte Response to beta-Amyloid Plaques in the Ageing Brain Associates with Cognitive Impairment. PLOS ONE, 10 (2). e0118463. ISSN 1932-6203

Mathur, R., Ince, P.G., Minett, T. et al. (6 more authors) (2015) A Reduced Astrocyte Response to β-Amyloid Plaques in the Ageing Brain Associates with Cognitive Impairment. PLoS One, 10 (2). e0118463. ISSN 1932-6203

Beer, A.M., Cooper-Knock, J., Higginbottom, A. et al. (8 more authors) (2014) Intermediate length C9orf72 expansion in an ALS patient without classical C9orf72 neuropathology. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 16 (3-4). pp. 249-251. ISSN 2167-8421

Cooper-Knock, J., Walsh, M.J., Higginbottom, A. et al. (9 more authors) (2014) Sequestration of multiple RNA recognition motif-containing proteins by C9orf72 repeat expansions. Brain, 137. 2040 - 2051. ISSN 0006-8950

Highley, J.R. orcid.org/0000-0002-4969-6526, Gebril, O.H., Simpson, J.E. et al. (9 more authors) (2014) Axonal Preservation in Deep Subcortical White Matter Lesions in the Ageing Brain. Journal of Aging Science, 2 (1).

Yang, D-J., Wang, X-L., Ismail, A. et al. (10 more authors) (2014) PTEN regulates AMPA receptor-mediated cell viability in iPS-derived motor neurons. Cell Death and Disease, 5. e1096. ISSN 2041-4889

Kirby, J., Highley, J.R., Cox, L. et al. (8 more authors) (2013) Lack of unique neuropathology in amyotrophic lateral sclerosis associated with p.K54E angiogenin (ANG) mutation. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, 39 (5). pp. 562-571. ISSN 0305-1846

Richardson, K., Allen, S.P., Mortiboys, H.J. et al. (5 more authors) (2013) The Effect of SOD1 Mutation on Cellular Bioenergetic Profile and Viability in Response to Oxidative Stress and Influence of Mutation-Type. PLoS ONE, 8 (6). e68256. ISSN 1932-6203

Turner, M.R., Hardiman, O., Benatar, M. et al. (17 more authors) (2013) Controversies and priorities in amyotrophic lateral sclerosis. The Lancet Neurology, 12 (3). pp. 310-322. ISSN 1474-4422

Brockington, A., Ning, K., Heath, P.R. et al. (7 more authors) (2013) Unravelling the enigma of selective vulnerability in neurodegeneration: motor neurons resistant to degeneration in ALS show distinct gene expression characteristics and decreased susceptibility to excitotoxicity. Acta Neuropathologica, 125 (1). pp. 95-109. ISSN 0001-6322

Kirby, J., Ning, K., Ferraiuolo, L. et al. (10 more authors) (2011) Phosphatase and tensin homologue/protein kinase B pathway linked to motor neuron survival in human superoxide dismutase 1-related amyotrophic lateral sclerosis. Brain, 134 (2). pp. 506-517. ISSN 0006-8950

Kirby, J., Goodall, E.F., Smith, W. et al. (10 more authors) (2010) Broad clinical phenotypes associated with TAR-DNA binding protein (TARDBP) mutations in amyotrophic lateral sclerosis. Neurogenetics, 11 (2). pp. 217-225. ISSN 1364-6745

Cox, L.E., Ferraiuolo, L., Goodall, E.F. et al. (13 more authors) (2010) Mutations in CHMP2B in lower motor neuron predominant amyotrophic lateral sclerosis (ALS). Plos One, 5 (3). Art no.e9872. ISSN 1932-6203

Van Deerlin, V.M., Sleiman, P.M.A., Martinez-Lage, M. et al. (97 more authors) (2010) Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP43 inclusions. Nature Genetics, 42 (3). pp. 234-239. ISSN 1061-4036,

Ihara, M., Polvikoski, T.M., Hall, R. et al. (7 more authors) (2010) Quantification of myelin loss in frontal lobe white matter in vascular dementia, Alzheimer's disease, and dementia with Lewy bodies. Acta Neuropathologica, 119 (5). pp. 579-589. ISSN 0001-6322

Mackenzie, I.R.A., Neumann, M., Bigio, E.H. et al. (18 more authors) (2010) Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update. Acta Neuropathologica, 119 (1). 1. ISSN 0001-6322

Proceedings Paper

Waller, S., Baxter, L., Fillingham, D. et al. (7 more authors) (2019) Iba-1-/CD68+microglia are a prominent feature of age-associated deep subcortical white matter lesions. In: Neuropathology and Applied Neurobiology. 120th Meeting of the British Neuropathological Society, Developmental Neuropathology Symposium, 06-08 Mar 2019, London, UK. Wiley , p. 33.

Pons, A.L., Shaw, P.J. orcid.org/0000-0002-8925-2567, Ince, P.G. et al. (5 more authors) (2016) Investigating the Mechanisms Underlying Oligodendrocyte Dysfunction in C9ORF72 ALS. In: Journal of Pathology. 9th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, 28/6/2016 - 1/7/2016, Nottingham, UK. Wiley , S13-S13.

Lorente-Pons, A., Wood, J.D., Shaw, P.J. orcid.org/0000-0002-8925-2567 et al. (5 more authors) (2016) Investigating the mechanisms underlying oligodendrocyte dysfunction in C9ORF72 ALS. In: NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. 117th meeting of the British Neuropathological Society, 2–4 March 2016, Royal College of Physicians, London. Wiley , p. 28.

This list was generated on Mon Aug 12 09:37:33 2019 BST.