Items where authors include "Caseley, EA"

Article

Yin, Y, Wei, L, Caseley, EA et al. (7 more authors) (2023) Leveraging the ATP-P2X7 receptor signalling axis to alleviate traumatic CNS damage and related complications. Medicinal Research Reviews, 43 (5). pp. 1346-1373. ISSN 0198-6325

Lara‐Reyna, S, Caseley, EA orcid.org/0000-0001-7591-143X, Topping, J et al. (4 more authors) (2022) Inflammasome activation: from molecular mechanisms to autoinflammation. Clinical & Translational Immunology, 11 (7). e1404. ISSN 2050-0068

Caseley, EA orcid.org/0000-0001-7591-143X, Muench, SP orcid.org/0000-0001-6869-4414 and Jiang, L-H orcid.org/0000-0001-6398-0411 (2022) Tyrosine 288 in the extracellular domain of the human P2X7 receptor is critical for receptor function revealed by structural modeling and site-directed mutagenesis. Proteins: Structure, Function, and Bioinformatics, 90 (3). pp. 619-624. ISSN 0887-3585

Caseley, EA orcid.org/0000-0001-7591-143X, Lara-Reyna, S, Poulter, JA orcid.org/0000-0003-2048-5693 et al. (6 more authors) (2022) An Atypical Autoinflammatory Disease Due to an LRR Domain NLRP3 Mutation Enhancing Binding to NEK7. Journal of Clinical Immunology, 42 (1). pp. 158-170. ISSN 0271-9142

Jiang, L-H orcid.org/0000-0001-6398-0411, Caseley, EA orcid.org/0000-0001-7591-143X, Muench, SP orcid.org/0000-0001-6869-4414 et al. (1 more author) (2021) Structural basis for the functional properties of the P2X7 receptor for extracellular ATP. Purinergic Signalling, 17 (3). pp. 331-344. ISSN 1573-9538

Caseley, EA, Muench, SP orcid.org/0000-0001-6869-4414 and Jiang, L-H orcid.org/0000-0001-6398-0411 (2020) Contribution of Val/Ile87 residue in the extracellular domain in agonist-induced current responses of the human and rat P2X7 receptors. Purinergic Signalling, 16 (4). pp. 485-490. ISSN 1573-9538

Caseley, EA orcid.org/0000-0001-7591-143X, Poulter, JA orcid.org/0000-0003-2048-5693, Rodrigues, F et al. (1 more author) (2020) Inflammasome inhibition under physiological and pharmacological conditions. Genes & Immunity, 21 (4). pp. 211-223. ISSN 1466-4879

Savic, S orcid.org/0000-0001-7910-0554, Caseley, EA orcid.org/0000-0001-7591-143X and McDermott, MF orcid.org/0000-0002-1015-0745 (2020) Moving towards a systems-based classification of innate immune-mediated diseases. Nature Reviews Rheumatology, 16 (4). pp. 222-237. ISSN 1759-4790

Lal, S, Caseley, EA, Hall, RM et al. (1 more author) (2018) Biological Impact of Silicon Nitride for Orthopaedic Applications: Role of Particle Size, Surface Composition and Donor Variation. Scientific Reports, 8 (1). 9109. ISSN 2045-2322

Caseley, EA, Muench, SP orcid.org/0000-0001-6869-4414 and Jiang, LH orcid.org/0000-0001-6398-0411 (2017) Conformational changes during human P2X7 receptor activation examined by structural modelling and cysteine-based cross-linking studies. Purinergic Signal, 13 (1). pp. 135-141. ISSN 1573-9538

Caseley, EA, Muench, SP orcid.org/0000-0001-6869-4414, Fishwick, CW orcid.org/0000-0003-1283-2181 et al. (1 more author) (2016) Structure-based identification and characterisation of structurally novel human P2X7 receptor antagonists. Biochemical Pharmacology, 116. pp. 130-139. ISSN 0006-2952

Caseley, EA, Muench, SP, Baldwin, SA et al. (3 more authors) (2015) Docking of competitive inhibitors to the P2X7 receptor family reveals key differences responsible for changes in response between rat and human. Bioorganic and Medicinal Chemistry Letters, 25 (16). 3164 - 3167. ISSN 0960-894X

Caseley, EA, Muench, SP, Roger, S et al. (3 more authors) (2014) Non-synonymous single nucleotide polymorphisms in the P2X receptor genes: Association with diseases, impact on receptor functions and potential use as diagnosis biomarkers. International Journal of Molecular Sciences, 15 (8). 13344 - 13371. ISSN 1661-6596