Items where authors include "Bryant, H.E."

Article

Fabbrizi, M.R. orcid.org/0000-0002-5156-1575, Nickson, C.M., Hughes, J.R. orcid.org/0000-0002-6420-2504 et al. (7 more authors) (2024) Targeting OGG1 and PARG radiosensitises head and neck cancer cells to high-LET protons through complex DNA damage persistence. Cell Death & Disease, 15 (2). 150. ISSN 2041-4889

Martínez-Alonso, M. orcid.org/0000-0002-0931-5274, Jones, C.G. orcid.org/0000-0003-2958-8322, Shipp, J.D. orcid.org/0000-0002-0452-8895 et al. (3 more authors) (2024) Phototoxicity of cyclometallated Ir(III) complexes bearing a thio-bis-benzimidazole ligand, and its monodentate analogue, as potential PDT photosensitisers in cancer cell killing. JBIC Journal of Biological Inorganic Chemistry, 29 (1). pp. 113-125. ISSN 0949-8257

Jackson, C.E., Doyle, I., Khan, H. et al. (7 more authors) (2024) Gelatin-containing porous polycaprolactone PolyHIPEs as substrates for 3D breast cancer cell culture and vascular infiltration. Frontiers in Bioengineering and Biotechnology, 11. 1321197. ISSN 2296-4185

Grant, E., Bucklain, F.A., Ginn, L. et al. (3 more authors) (2022) Progesterone receptor expression contributes to gemcitabine resistance at higher ECM stiffness in breast cancer cell lines. PLoS ONE, 17 (5). e0268300.

King, D., Southgate, H.E.D., Roetschke, S. et al. (10 more authors) (2021) Increased replication stress determines ATR inhibitor sensitivity in neuroblastoma cells. Cancers, 13 (24). 6215. ISSN 2072-6694

Aguilar Cosme, J.R., Gagui, D.C., Bryant, H.E. et al. (1 more author) (2021) Morphological response in cancer spheroids for screening photodynamic therapy parameters. Frontiers in Molecular Biosciences, 8 (11). 784962. ISSN 2296-889X

Aguilar Cosme, J.R., Gagui, D.C., Green, N.H. orcid.org/0000-0001-5413-0642 et al. (2 more authors) (2021) In vitro low-fluence photodynamic therapy parameter screening using 3D tumor spheroids shows that fractionated light treatments enhance phototoxicity. ACS Biomaterials Science & Engineering, 7 (11). pp. 5078-5089. ISSN 2373-9878

Piberger, A.L., Bowry, A., Kelly, R.D.W. et al. (8 more authors) (2020) PrimPol-dependent single-stranded gap formation mediates homologous recombination at bulky DNA adducts. Nature Communications, 11 (1). 5863. ISSN 2041-1723

Halliwell, J.A., Gravells, P. and Bryant, H.E. orcid.org/0000-0003-2720-7020 (2020) DNA fiber assay for the analysis of DNA replication progression in human pluripotent stem cells. Current Protocols in Stem Cell Biology, 54 (1). e115. ISSN 1941-7322

George, S.L., Lorenzi, F., King, D. et al. (14 more authors) (2020) Therapeutic vulnerabilities in the DNA damage response for the treatment of ATRX mutant neuroblastoma. EBioMedicine, 59. 102971. ISSN 2352-3964

Harrision, D., Gravells, P., Thompson, R. et al. (1 more author) (2020) Poly(ADP-Ribose) glycohydrolase (PARG) vs. poly(ADP-Ribose) polymerase (PARP) – function in genome maintenance and relevance of inhibitors for anti-cancer therapy. Frontiers in Molecular Biosciences, 7. 191. ISSN 2296-889X

King, D., Li, X.D., Almeida, G.S. et al. (13 more authors) (2020) MYCN expression induces replication stress and sensitivity to PARP inhibition in neuroblastoma. Oncotarget, 11 (23). pp. 2141-2159.

Kim, H.R., Santhakumar, K., Markham, E. et al. (5 more authors) (2020) Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish. Oncotarget, 11 (13). pp. 1109-1130. ISSN 1949-2553

Doherty, R.E., Bryant, H.E., Valluru, M.K. et al. (2 more authors) (2019) Increased non-homologous end joining makes DNA-PK a promising target for therapeutic intervention in uveal melanoma. Cancers, 11 (9). ISSN 2072-6694

Aguilar Cosme, J.R. orcid.org/0000-0001-7933-3905, Bryant, H.E. and Claeyssens, F. orcid.org/0000-0002-1030-939X (2019) Carbon dot-protoporphyrin IX conjugates for improved drug delivery and bioimaging. PLoS ONE, 14 (7). e0220210. ISSN 1932-6203

Crowston, B., Shipp, J., Chekulaev, D.M. et al. (8 more authors) (2019) Heteronuclear d-d and d-f Ru(II)/M complexes [M = Gd(III), Yb(III), Nd(III), Zn(II) or Mn(II)] of ligands combining phenanthroline and aminocarboxylate binding sites: combined relaxivity, cell imaging and photophysical studies. Dalton Transactions, 48 (18). pp. 6132-6152. ISSN 1477-9226

Willan, J., Cleasby, A.J., Flores-Rodriguez, N. et al. (7 more authors) (2019) ESCRT-III is necessary for the integrity of the nuclear envelope in micronuclei but is aberrant at ruptured micronuclear envelopes generating damage. Oncogenesis, 8 (5). 29. ISSN 2157-9024

Kadhim, A., McKenzie, L.K., Bryant, H.E. et al. (1 more author) (2019) Synthesis and aggregation of a porphyrin cored hyperbranched polyglycidol and its application as a macromolecular photosensitizer for photodynamic therapy. Molecular Pharmaceutics, 16 (3). pp. 1132-1139. ISSN 1543-8384

McKenzie, L.K., Bryant, H.E. and Weinstein, J.A. (2019) Transition metal complexes as photosensitisers in one- and two-photon photodynamic therapy. Coordination Chemistry Reviews, 379. pp. 2-29. ISSN 0010-8545

Omar, S.A.E., Scattergood, P.A. orcid.org/0000-0001-9070-5933, McKenzie, L.K. et al. (7 more authors) (2018) Photophysical and Cellular Imaging Studies of Brightly Luminescent Osmium(II) Pyridyltriazole Complexes. Inorganic Chemistry . ISSN 0020-1669

Daniels, R.E., McKenzie, L.K., Shewring, J.R. et al. (3 more authors) (2018) Pyridazine-bridged cationic diiridium complexes as potential dual-mode bioimaging probes. RSC ADVANCES, 8 (18). pp. 9670-9676. ISSN 2046-2069

Gravells, P., Neale, J., Grant, E. et al. (4 more authors) (2018) Radiosensitization with an inhibitor of poly(ADP-ribose) glycohydrolase: A comparison with the PARP1/2/3 inhibitor olaparib. DNA Repair , 61. pp. 25-36. ISSN 1568-7864

Gravells, P.L., Grant, E., Smith, K.M. et al. (2 more authors) (2017) Specific killing of DNA damage-response deficient cells with inhibitors of poly(ADP-ribose) glycohydrolase. DNA Repair, 52. pp. 81-91. ISSN 1568-7864

Mateo, J., Boysen, G., Barbieri, C.E. et al. (7 more authors) (2017) DNA Repair in Prostate Cancer: Biology and Clinical Implications. European Urology, 71 (3). pp. 417-425. ISSN 0302-2838

McKenzie, L., Sazanovich, I., Baggaley, E. et al. (5 more authors) (2016) Metal Complexes For Two-photon Photodynamic Therapy: A Cyclometallated Iridium Complex Induces Two-photon Photosensitization of Cancer Cells Under Near-IR Light. Chemistry - A European Journal. ISSN 0947-6539

Omar, S.A.E., Scattergood, P.A., McKenzie, L.K. et al. (3 more authors) (2016) Towards Water Soluble Mitochondria-Targeting Theranostic Osmium(II) Triazole-Based Complexes. Molecules , 21 (10). 1382. ISSN 1420-3049

Omar, S.A., Scattergood, P.A., McKenzie, L.K. et al. (3 more authors) (2016) Towards Water Soluble Mitochondria-Targeting Theranostic Osmium(II) Triazole-Based Complexes. Molecules, 21 (10). ISSN 1420-3049

Patterson, K., Arya, L., Bottomley, S. et al. (4 more authors) (2016) Altered RECQL5 expression in urothelial bladder carcinoma increases cellular proliferation and makes RECQL5 helicase activity a novel target for chemotherapy. Oncotarget, 7. pp. 76140-76150. ISSN 1949-2553

Jana, A., Crowston, B.J., Shewring, J.R. et al. (7 more authors) (2016) Heteronuclear Ir(III)–Ln(III) Luminescent Complexes: Small-Molecule Probes for Dual Modal Imaging and Oxygen Sensing. Inorganic Chemistry, 55 (11). pp. 5623-5633. ISSN 0020-1669

Doherty, R.E., Sazanovich, I.V., McKenzie, L.K. et al. (6 more authors) (2016) Photodynamic killing of cancer cells by a Platinum(II) complex with cyclometallating ligand. SCIENTIFIC REPORTS, 6. ARTN 22668. ISSN 2045-2322

Arora, A., Abdel-Fatah, T.M.A., Agarwal, D. et al. (14 more authors) (2016) Clinicopathological and prognostic significance of RECQL5 helicase expression in breast cancers. Carcinogenesis, 37 (1). pp. 63-71. ISSN 0143-3334

Drayton, R.M., Rehman, I., Clarke, R. et al. (13 more authors) (2015) Identification and Diagnostic Performance of a Small RNA within the PCA3 and BMCC1 Gene Locus That Potentially Targets mRNA. Cancer Epidemiology, Biomarkers and Prevention, 24 (1). 268 - 275. ISSN 1055-9965

Lafta, I.J., Bryant, H.E. and Goldman, A.S.H. (2014) 'Sex' in the cancer cell. Oncotarget, 5 (18). pp. 7984-7985.

Drayton, R.M., Peter, S., Myers, K. et al. (4 more authors) (2014) MicroRNA-99a and 100 mediated upregulation of FOXA1 in bladder cancer. Oncotarget, 5 (15). pp. 6375-6386.

Drayton, R.M., Dudziec, E., Peter, S. et al. (4 more authors) (2014) Reduced Expression of miRNA-27a Modulates Cisplatin Resistance in Bladder Cancer by Targeting the Cystine/Glutamate Exchanger SLC7A11. Clinical Cancer Research, 20 (7). pp. 1990-2000. ISSN 1078-0432

Gravells, P., Hoh, L., Solovieva, S. et al. (5 more authors) (2013) Reduced FANCD2 influences spontaneous SCE and RAD51 foci formation in uveal melanoma and Fanconi anaemia. Oncogene, 32 (46). pp. 5338-5346. ISSN 0950-9232

Eccles, S.A., Aboagye, E.O., Ali, S. et al. (84 more authors) (2013) Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer. Breast Cancer Research, 15. R92. ISSN 1465-5411

Ying, S.M., Myers, K., Bottomley, S. et al. (2 more authors) (2009) BRCA2-dependent homologous recombination is required for repair of Arsenite-induced replication lesions in mammalian cells. Nucleic Acids Research, 37 (15). pp. 5105-5113. ISSN 0305-1048

Bryant, H.E. and Helleday, T. (2006) Inhibition of poly (ADP-ribose) polymerase activates ATM which is required for subsequent homologous recombination repair. Nucleic Acids Research, 34 (6). pp. 1685-1691. ISSN 0305-1048

Proceedings Paper

Jackson, C.E., Green, N., English, W. et al. (2 more authors) (2023) Production of porous polycaprolactone polyHIPEs as substrates for in vitro 3D breast cancer cell culture. In: Tissue Engineering Part A. Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Meeting 2023, 28-31 Mar 2023, Manchester, UK. Mary Ann Liebert .

Preprint

Saldana-Guerrero, I.M. orcid.org/0000-0003-4064-185X, Montano-Gutierrez, L.F. orcid.org/0000-0003-2383-1483, Hafemeister, C. orcid.org/0000-0001-6365-8254 et al. (22 more authors) (2022) Neuroblastoma-associated chromosomal aberrations drive cell identity loss in human neural crest via disruption of developmental regulators. [Preprint] (Submitted)