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Number of items at this level: 61.


Azam, AA, Kinder, JM, Khan, GN et al. (9 more authors) (2018) Production of membrane proteins for characterisation of their pheromone-sensing and antimicrobial resistance functions. European Biophysics Journal, 47 (7). pp. 723-737. ISSN 0175-7571


Baum, J, Chiti, F, De Simone, A et al. (9 more authors) (2019) Homage to Chris Dobson. Frontiers in Molecular Biosciences, 6. 137. ISSN 2296-889X

Benseny-Cases, N, Karamanos, TK, Hoop, CL et al. (2 more authors) (2019) Extracellular matrix components modulate different stages in β2-microglobulin amyloid formation. The Journal of biological chemistry, 294. pp. 9392-9401. ISSN 0021-9258

Berry, A and Radford, SE (2018) Richard Nelson Perham. 27 April 1937—14 February 2015. Biographical Memoirs of Fellows of the Royal Society, 65. pp. 317-339. ISSN 0080-4606

Bunce, SJ, Wang, Y, Stewart, KL et al. (4 more authors) (2019) Molecular Insights into the surface catalyzed secondary nucleation of Amyloid-β40 (Aβ40) by the peptide fragment Aβ16-22. Science Advances, 5 (6). eaav8216. ISSN 2375-2548

Byrne, MJ, Steele, JFC, Hesketh, EL et al. (4 more authors) (2019) Combining Transient Expression and Cryo-EM to Obtain High-Resolution Structures of Luteovirid Particles. Structure, 27 (12). 1761-1770.e3. ISSN 0969-2126


Calabrese, AN, Jackson, SM, Jones, LN et al. (10 more authors) (2017) Topological dissection of the membrane transport protein Mhp1 derived from cysteine accessibility and mass spectrometry. Analytical Chemistry, 89 (17). pp. 8844-8852. ISSN 0003-2700

Calabrese, AN and Radford, SE (2018) Mass spectrometry-enabled structural biology of membrane proteins. Methods, 147. pp. 187-205. ISSN 1046-2023

Chau, CC, Radford, SE, Hewitt, EW et al. (1 more author) (2020) Macromolecular Crowding Enhances the Detection of DNA and Proteins by a Solid-State Nanopore. Nano Letters, 20 (7). pp. 5553-5561. ISSN 1530-6984

Ciano, L, Paradisi, A, Hemsworth, GR et al. (3 more authors) (2020) Insights from semi-oriented EPR spectroscopy studies into the interaction of lytic polysaccharide monooxygenases with cellulose. Dalton Transactions, 49 (11). pp. 3413-3422. ISSN 1477-9226

Cornwell, O, Bond, NJ, Radford, SE et al. (1 more author) (2019) Long-Range Conformational Changes in Monoclonal Antibodies Revealed Using FPOP-LC-MS/MS. Analytical Chemistry, 91 (23). pp. 15163-15170. ISSN 0003-2700

Cornwell, O, Radford, SE, Ashcroft, AE et al. (1 more author) (2018) Comparing Hydrogen Deuterium Exchange and Fast Photochemical Oxidation of Proteins: a Structural Characterisation of Wild-Type and ΔN6 β₂-Microglobulin. Journal of The American Society for Mass Spectrometry, 29 (12). pp. 2413-2426. ISSN 1044-0305


Devine, PWA, Fisher, HC, Calabrese, AN et al. (6 more authors) (2017) Investigating the Structural Compaction of Biomolecules Upon Transition to the Gas-Phase Using ESI-TWIMS-MS. Journal of The American Society for Mass Spectrometry, 28 (9). pp. 1855-1862. ISSN 1044-0305

Dobson, CL, Devine, PWA, Phillips, JJ et al. (24 more authors) (2016) Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo. Scientific Reports, 6. 38644. ISSN 2045-2322

Drulyte, I, Obajdin, J, Trinh, CH et al. (4 more authors) (2019) Crystal structure of the putative cyclase IdmH from the indanomycin nonribosomal peptide synthase/polyketide synthase. IUCrJ, 6 (6). pp. 1120-1133. ISSN 2052-2525


Fessl, T, Watkins, D, Oatley, P et al. (7 more authors) (2018) Dynamic action of the Sec machinery during initiation, protein translocation and termination. eLife, 7. e35112. ISSN 2050-084X

Foley, MH, Déjean, G, Hemsworth, GR et al. (3 more authors) (2019) A Cell-Surface GH9 Endo-Glucanase Coordinates with Surface Glycan Binding Proteins to Mediate Xyloglucan Uptake in the Gut Symbiont Bacteroides ovatus. Journal of Molecular Biology, 431 (5). pp. 981-995. ISSN 0022-2836

Fowler, CA, Hemsworth, GR, Cuskin, F et al. (5 more authors) (2018) Structure and function of a glycoside hydrolase family 8 endoxylanase from Teredinibacter turnerae. Acta Crystallographica Section D: Structural Biology, 74 (10). pp. 946-955. ISSN 2059-7983

Fowler, CA, Sabbadin, F, Ciano, L et al. (6 more authors) (2019) Discovery, activity and characterisation of an AA10 lytic polysaccharide oxygenase from the shipworm symbiont Teredinibacter turnerae. Biotechnology for Biofuels, 12. ARTN: 232. ISSN 1754-6834

Frandsen, KEH, Tovborg, M, Jørgensen, CI et al. (15 more authors) (2019) Insights into an unusual Auxiliary Activity 9 family member lacking the histidine brace motif of lytic polysaccharide monooxygenases. The Journal of Biological Chemistry, 294 (45). pp. 17117-17130. ISSN 0021-9258


Gallardo, R, Iadanza, MG, Xu, Y et al. (4 more authors) (2020) Fibril structures of diabetes-related amylin variants reveal a basis for surface-templated assembly. Nature Structural & Molecular Biology. ISSN 1545-9993

Gallardo, R, Ranson, NA and Radford, SE (2020) Amyloid Structures: Much More Than Just A Cross-β Fold. Current Opinion in Structural Biology, 60. pp. 7-16. ISSN 0959-440X

Gregory, RC, Hemsworth, GR, Turkenburg, JP et al. (3 more authors) (2016) Activity, stability and 3-D structure of the Cu(II) form of a chitin-active lytic polysaccharide monooxygenase from Bacillus amyloliquefaciens. Dalton Transactions, 45 (42). pp. 16904-16912. ISSN 1477-9226


Heirbaut, M, Lermyte, F, Martin, EM et al. (4 more authors) (2017) Specific Sequences in the N-terminal Domain of Human Small Heat Shock Protein HSPB6 Dictate Preferential Heterooligomerization with the Orthologue HSPB1. Journal of Biological Chemistry, 292 (24). pp. 9944-9957. ISSN 0021-9258

Heirbaut, M, Lermyte, F, Martin, EM et al. (5 more authors) (2016) The preferential heterodimerization of human small heat shock proteins HSPB1 and HSPB6 is dictated by the N-terminal domain. Archives of Biochemistry and Biophysics, 610. pp. 41-50. ISSN 0003-9861

Hemsworth, GR, Ciano, L, Davies, GJ et al. (1 more author) (2018) Chapter Three - Production and spectroscopic characterization of lytic polysaccharide monooxygenases. Methods in Enzymology, 613. pp. 63-90. ISSN 0076-6879

Hemsworth, GR, Moroz, OV, Fogg, MJ et al. (4 more authors) (2011) The Crystal Structure of the Leishmania major Deoxyuridine Triphosphate Nucleotidohydrolase in Complex with Nucleotide Analogues, dUMP, and Deoxyuridine. Journal of Biological Chemistry, 286 (18). pp. 16470-16481. ISSN 0021-9258

Hethershaw, EL, Adamson, PJ, Smith, KA et al. (7 more authors) (2018) The role of β‐barrels 1 and 2 in the enzymatic activity of factor XIII A‐subunit. Journal of Thrombosis and Haemostasis, 16 (7). pp. 1391-1401. ISSN 1538-7933

Hoop, CL, Zhu, J, Bhattacharya, S et al. (3 more authors) (2020) Collagen I weakly interacts with the β-sheets of β2-microglobulin and enhances conformational exchange to induce amyloid formation. Journal of the American Chemical Society, 142 (3). pp. 1321-1331. ISSN 0002-7863


Iadanza, MG, Jackson, MP, Hewitt, EW et al. (2 more authors) (2018) A new era for understanding amyloid structures and disease. Nature Reviews Molecular Cell Biology, 19 (12). pp. 755-773. ISSN 1471-0072

Iadanza, MG, Silvers, R, Boardman, J et al. (7 more authors) (2018) The structure of a β₂-microglobulin fibril suggests a molecular basis for its amyloid polymorphism. Nature Communications, 9. 4517. ISSN 2041-1723


Jackson, MP and Hewitt, EW (2017) Why are Functional Amyloids Non-Toxic in Humans? Biomolecules, 7 (4). 71. ISSN 2218-273X


Karamanos, TK, Jackson, MP, Calabrese, AN et al. (6 more authors) (2019) Structural mapping of oligomeric intermediates in an amyloid assembly pathway. eLife, 8. e46574. ISSN 2050-084X

Karamanos, TK, Kalverda, AP, Thompson, GS et al. (1 more author) (2014) Visualization of transient protein-protein interactions that promote or inhibit amyloid assembly. Molecular Cell, 55 (2). pp. 214-226. ISSN 1097-2765

Karamanos, TK, Pashley, CL, Kalverda, AP et al. (4 more authors) (2016) A population shift between sparsely populated folding intermediates determines amyloidogenicity. Journal of the American Chemical Society, 138 (19). pp. 6271-6280. ISSN 0002-7863

Knight, PD, Karamanos, TK, Radford, SE et al. (1 more author) (2018) Identification of a novel site of interaction between ataxin-3 and the amyloid aggregation inhibitor polyglutamine binding peptide 1. European Journal of Mass Spectrometry, 24 (1). pp. 129-140. ISSN 1469-0667

Kontziampasis, D, Klebl, DP, Iadanza, MG et al. (7 more authors) (2019) A cryo-EM grid preparation device for time-resolved structural studies. IUCrJ, 6 (6). ISSN 2052-2525


Lauwers, E, Lalli, G, Brandner, S et al. (34 more authors) (2020) Potential human transmission of amyloid-β pathology: surveillance and risks. Lancet Neurology. ISSN 1474-4422 (In Press)


Martin, EM, Jackson, MP, Gamerdinger, M et al. (6 more authors) (2018) Conformational flexibility within the nascent polypeptide–associated complex enables its interactions with structurally diverse client proteins. Journal of Biological Chemistry, 293 (22). pp. 8554-8568. ISSN 0021-9258


Rodríguez-Alonso, R, Létoquart, J, Nguyen, VS et al. (7 more authors) (2020) Structural insight into the formation of lipoprotein-β-barrel complexes. Nature Chemical Biology. ISSN 1552-4450

Roth, C, Chan, S, Offen, WA et al. (7 more authors) (2017) Structural and functional insight into human O-GlcNAcase. Nature Chemical Biology, 13 (6). pp. 610-612. ISSN 1552-4469


Sabbadin, F, Hemsworth, GR, Ciano, L et al. (17 more authors) (2018) An ancient family of lytic polysaccharide monooxygenases with roles in arthropod development and biomass digestion. Nature Communications, 9. 756. ISSN 2041-1723

Scarff, CA, Ashcroft, AE and Radford, SE (2016) Characterization of Amyloid Oligomers by Electrospray Ionization-Ion Mobility Spectrometry-Mass Spectrometry (ESI-IMS-MS). In: Eliezer, D, (ed.) Protein Amyloid Aggregation: methods and protocols. Methods in Molecular Biology, 1345 . Springer (Humana Press) , New York, N.Y., U.S.A. , pp. 115-132. ISBN 978-1-4939-2977-1

Scarff, CA, Fuller, MJG, Thompson, RF et al. (1 more author) (2018) Variations on Negative Stain Electron Microscopy Methods: Tools for Tackling Challenging Systems. Journal of Visualized Experiments (132). e57199.

Shen, K, Gamerdinger, M, Chan, R et al. (12 more authors) (2019) Dual Role of Ribosome-Binding Domain of NAC as a Potent Suppressor of Protein Aggregation and Aging-Related Proteinopathies. Molecular Cell, 74 (4). 729-741.e7. ISSN 1097-2765

Smith, HI, Guthertz, N, Cawood, EE et al. (3 more authors) (2020) The role of the IT-state in D76N β2-microglobulin amyloid assembly: a crucial intermediate or an innocuous bystander? Journal of Biological Chemistry. jbc.RA120.014901. ISSN 0021-9258

Stewart, KL, Hughes, E, Yates, EA et al. (2 more authors) (2017) Molecular Origins of the Compatibility Between Glycosaminoglycans and Aβ40 Amyloid Fibrils. Journal of Molecular Biology, 429 (16). pp. 2449-2462. ISSN 0022-2836

Stewart, KL and Radford, SE (2017) Amyloid Plaques Beyond Aβ: A Survey of the Diverse Modulators of Amyloid Aggregation. Biophysical Reviews, 9 (4). pp. 405-419. ISSN 1867-2450

Stull, F, Koldewey, P, Humes, JR et al. (2 more authors) (2016) Substrate protein folds while it is bound to the ATP-independent chaperone Spy. Nature Structural and Molecular Biology, 23 (1). pp. 53-58. ISSN 1545-9993


Tamura, K, Hemsworth, GR, Dejean, G et al. (7 more authors) (2017) Molecular mechanism by which prominent human gut Bacteroidetes utilize mixed-linkage beta-glucans, major health-promoting cereal polysaccharides. Cell Reports, 21 (2). pp. 417-430. ISSN 2211-1247

Tamura, K, Hemsworth, GR, Déjean, G et al. (7 more authors) (2017) Correction to: Molecular Mechanism by which Prominent Human Gut Bacteroidetes Utilize Mixed-Linkage Beta-Glucans, Major Health-Promoting Cereal Polysaccharides. Cell Reports, 21 (7). p. 2030. ISSN 2211-1247

Thompson, RF, Iadanza, MG, Hesketh, EL et al. (2 more authors) (2018) Collection, pre-processing and on-the-fly analysis of data for high-resolution, single-particle cryo-electron microscopy. Nature Protocols, 14. pp. 100-118. ISSN 1754-2189

Townsend, D, Hughes, E, Akien, G et al. (4 more authors) (2018) Epigallocatechin-3-gallate remodels apolipoprotein A-I amyloid fibrils into soluble oligomers in the presence of heparin. Journal of Biological Chemistry, 293 (33). pp. 12877-12893. ISSN 0021-9258

Townsend, D, Hughes, E, Stewart, KL et al. (3 more authors) (2018) Orientation of a Diagnostic Ligand Bound to Macroscopically Aligned Amyloid-ß Fibrils Determined by Solid-state NMR. Journal of Physical Chemistry Letters, 9 (22). pp. 6611-6615. ISSN 1948-7185


Ulamec, SM and Radford, SE (2020) Spot the Difference: Function versus Toxicity in Amyloid Fibrils. Trends in Biochemical Sciences. ISSN 0968-0004


Walko, M, Hewitt, E, Radford, SE et al. (1 more author) (2019) Design and Synthesis of Cysteine-Specific Labels for Photo-Crosslinking Studies. RSC Advances, 9 (14). pp. 7610-7614. ISSN 2046-2069

Wang, Y, Bunce, SJ, Radford, SE et al. (3 more authors) (2019) Thermodynamic phase diagram of amyloid-β (16-22) peptide. Proceedings of the National Academy of Sciences of the United States of America, 116 (6). pp. 2091-2096. ISSN 0027-8424

Watkinson, TG, Calabrese, AN, Ault, JR et al. (2 more authors) (2017) FPOP-LC-MS/MS Suggests Differences in Interaction Sites of Amphipols and Detergents with Outer Membrane Proteins. Journal of the American Society for Mass Spectrometry, 28 (1). pp. 50-55. ISSN 1044-0305


Young, LM, Ashcroft, AE and Radford, SE (2017) Small molecule probes of protein aggregation. Current Opinion in Chemical Biology, 39. pp. 90-99. ISSN 1367-5931

Young, LM, Saunders, JC, Mahood, RA et al. (6 more authors) (2015) Screening and classifying small-molecule inhibitors of amyloid formation using ion mobility spectrometry-mass spectrometry. Nature Chemistry, 7 (1). pp. 73-81. ISSN 1755-4330

Young, LM, Tu, LH, Raleigh, D et al. (2 more authors) (2017) Understanding co-polymerization in amyloid formation by direct observation of mixed oligomers. Chemical Science, 8 (7). pp. 5030-5040. ISSN 2041-6520

This list was generated on Wed Oct 21 04:37:11 2020 BST.