Items where Funder is Leeds Teaching Hospitals Charitable Foundation.

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Lee, RW, Danson, S, Elliot, M et al. (8 more authors) (2022) Importance of clinical research for the UK's 10-year cancer plan. The Lancet Oncology. ISSN 1470-2045

004-2018

Tanner, G., Barrow, R., Ajaib, S. et al. (27 more authors) (2024) IDHwt glioblastomas can be stratified by their transcriptional response to standard treatment, with implications for targeted therapy. Genome Biology, 25. 45. ISSN 1474-760X

078606/Z/05/Z

Ouboussad, L, Wong, C, Hunt, L et al. (3 more authors) (2016) A2.40 Investigating IL-6 pathway signalling kinetics in peripheral blood single cell subsets with tocilizumab therapy in patients with early rheumatoid arthritis. In: Annals of the Rheumatic Diseases. 36th European Workshop for Rheumatology Research, 25-27 Feb 2016, York, UK. BMJ Publishing Group , A31-A31.

088908/Z/09/Z

Zakkaroff, C orcid.org/0000-0003-3668-8794, Biglands, JD orcid.org/0000-0002-1161-5022, Greenwood, JP orcid.org/0000-0002-2861-0914 et al. (4 more authors) (2018) Patient-specific coronary blood supply territories for quantitative perfusion analysis. Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization, 6 (2). pp. 137-154. ISSN 2168-1163

Zakkaroff, C orcid.org/0000-0003-3668-8794, Biglands, JD orcid.org/0000-0002-1161-5022, Greenwood, JP orcid.org/0000-0002-2861-0914 et al. (4 more authors) (2018) Patient-specific coronary blood supply territories for quantitative perfusion analysis. Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization, 6 (2). pp. 137-154. ISSN 2168-1163

105615/Z/14/Z

Robinson, JI orcid.org/0000-0001-5425-7520, Md Yusof, MY orcid.org/0000-0003-3131-9121, Davies, V et al. (20 more authors) (2022) Comprehensive genetic and functional analyses of Fc gamma receptors influence on response to rituximab therapy for autoimmunity. eBioMedicine, 86. 104343. ISSN 2352-3964

13/192

Rippaus, N, Taggart, D, Williams, J et al. (4 more authors) (2016) Metastatic site-specific polarization of macrophages in intracranial breast cancer metastases. Oncotarget, 7 (27). pp. 41473-41487.

Rippaus, N, Williams, J, Taggart, D et al. (3 more authors) (2016) Dural and parenchymal brain metastases in breast cancer are characterized by distinct inflammatory tumour microenvironments. In: Cancer Research. AACR Special Conference on Tumor Metastasis, 30 Nov - 03 Dec 2016, Austin, Texas, USA. American Association for Cancer Research .

17855

Ouboussad, L, Wong, C, Hunt, L et al. (3 more authors) (2016) A2.40 Investigating IL-6 pathway signalling kinetics in peripheral blood single cell subsets with tocilizumab therapy in patients with early rheumatoid arthritis. In: Annals of the Rheumatic Diseases. 36th European Workshop for Rheumatology Research, 25-27 Feb 2016, York, UK. BMJ Publishing Group , A31-A31.

17969

Robinson, JI orcid.org/0000-0001-5425-7520, Md Yusof, MY orcid.org/0000-0003-3131-9121, Davies, V et al. (20 more authors) (2022) Comprehensive genetic and functional analyses of Fc gamma receptors influence on response to rituximab therapy for autoimmunity. eBioMedicine, 86. 104343. ISSN 2352-3964

18387

Ouboussad, L, Wong, C, Hunt, L et al. (3 more authors) (2016) A2.40 Investigating IL-6 pathway signalling kinetics in peripheral blood single cell subsets with tocilizumab therapy in patients with early rheumatoid arthritis. In: Annals of the Rheumatic Diseases. 36th European Workshop for Rheumatology Research, 25-27 Feb 2016, York, UK. BMJ Publishing Group , A31-A31.

19764

Robinson, JI orcid.org/0000-0001-5425-7520, Md Yusof, MY orcid.org/0000-0003-3131-9121, Davies, V et al. (20 more authors) (2022) Comprehensive genetic and functional analyses of Fc gamma receptors influence on response to rituximab therapy for autoimmunity. eBioMedicine, 86. 104343. ISSN 2352-3964

1T01-A321

Hassanieh, S., Domingo, E., Blake, A. et al. (16 more authors) (2022) 337P Prediction of poor response to oxaliplatin by an RNA signature derived and validated in colorectal cancer clinical trials. In: Annals of Oncology. ESMO Congress 2022, 09-13 Sep 2022, Paris, France. Elsevier , S691.

Seligmann, JF, Domingo, E, Fisher, D et al. (17 more authors) (2022) The clinical relevance of tumor RAS/TP53 dual mutation in early and metastatic colorectal cancer (CRC). In: 2022 ASCO Annual Meeting, 03-07 Jun 2022, Chicago, Il, USA and Online.

Hoorn, ST, Sommeijer, DW, Elliot, F et al. (12 more authors) (2021) Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone. British Journal of Cancer. ISSN 0007-0920

Williams, C. orcid.org/0000-0002-1574-653X, Seligmann, J.F. orcid.org/0000-0003-4379-6005, Guetter, C. et al. (13 more authors) (2021) Artificial intelligence-assisted immunohistochemical (IHC) evaluation of tumor amphiregulin (AREG) and epiregulin (EREG) expression as a combined predictive biomarker for panitumumab (Pan) therapy benefit in RAS wild-type (wt) metastatic colorectal cancer (mCRC): Analysis within the phase III PICCOLO trial. In: Journal of Clinical Oncology. 2021 Gastrointestinal Cancers Symposium, 15-17 Jan 2021, Online. American Society of Clinical Oncology , p. 111.

Platt, JR, Todd, OM orcid.org/0000-0001-7212-8095, Hall, P et al. (14 more authors) (2023) FOxTROT2: innovative trial design to evaluate the role of neoadjuvant chemotherapy for treating locally advanced colon cancer in older adults or those with frailty. ESMO Open, 8 (1). 100642. ISSN 2059-7029

Brown, LC, Graham, J, Fisher, D et al. (15 more authors) (2022) Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer. Clinical Trials, 19 (2). pp. 146-157. ISSN 1740-7745

200923

Ouboussad, L, Wong, C, Hunt, L et al. (3 more authors) (2016) A2.40 Investigating IL-6 pathway signalling kinetics in peripheral blood single cell subsets with tocilizumab therapy in patients with early rheumatoid arthritis. In: Annals of the Rheumatic Diseases. 36th European Workshop for Rheumatology Research, 25-27 Feb 2016, York, UK. BMJ Publishing Group , A31-A31.

Ouboussad, L, Wong, C, Hunt, L et al. (3 more authors) (2016) A2.40 Investigating IL-6 pathway signalling kinetics in peripheral blood single cell subsets with tocilizumab therapy in patients with early rheumatoid arthritis. In: Annals of the Rheumatic Diseases. 36th European Workshop for Rheumatology Research, 25-27 Feb 2016, York, UK. BMJ Publishing Group , A31-A31.

2012-005111-12

Seligmann, JF, Domingo, E, Fisher, D et al. (17 more authors) (2022) The clinical relevance of tumor RAS/TP53 dual mutation in early and metastatic colorectal cancer (CRC). In: 2022 ASCO Annual Meeting, 03-07 Jun 2022, Chicago, Il, USA and Online.

Seligmann, JF, Domingo, E, Fisher, D et al. (17 more authors) (2022) The clinical relevance of tumor RAS/TP53 dual mutation in early and metastatic colorectal cancer (CRC). In: 2022 ASCO Annual Meeting, 03-07 Jun 2022, Chicago, Il, USA and Online.

Brown, LC, Graham, J, Fisher, D et al. (15 more authors) (2022) Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer. Clinical Trials, 19 (2). pp. 146-157. ISSN 1740-7745

Brown, LC, Graham, J, Fisher, D et al. (15 more authors) (2022) Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer. Clinical Trials, 19 (2). pp. 146-157. ISSN 1740-7745

201718-08

Tanner, G., Barrow, R., Ajaib, S. et al. (27 more authors) (2024) IDHwt glioblastomas can be stratified by their transcriptional response to standard treatment, with implications for targeted therapy. Genome Biology, 25. 45. ISSN 1474-760X

204825/Z/16/Z

Robinson, JI orcid.org/0000-0001-5425-7520, Md Yusof, MY orcid.org/0000-0003-3131-9121, Davies, V et al. (20 more authors) (2022) Comprehensive genetic and functional analyses of Fc gamma receptors influence on response to rituximab therapy for autoimmunity. eBioMedicine, 86. 104343. ISSN 2352-3964

223404

Ouboussad, L, Wong, C, Hunt, L et al. (3 more authors) (2016) A2.40 Investigating IL-6 pathway signalling kinetics in peripheral blood single cell subsets with tocilizumab therapy in patients with early rheumatoid arthritis. In: Annals of the Rheumatic Diseases. 36th European Workshop for Rheumatology Research, 25-27 Feb 2016, York, UK. BMJ Publishing Group , A31-A31.

276

Ouboussad, L, Wong, C, Hunt, L et al. (3 more authors) (2016) A2.40 Investigating IL-6 pathway signalling kinetics in peripheral blood single cell subsets with tocilizumab therapy in patients with early rheumatoid arthritis. In: Annals of the Rheumatic Diseases. 36th European Workshop for Rheumatology Research, 25-27 Feb 2016, York, UK. BMJ Publishing Group , A31-A31.

29062

Zakkaroff, C orcid.org/0000-0003-3668-8794, Biglands, JD orcid.org/0000-0002-1161-5022, Greenwood, JP orcid.org/0000-0002-2861-0914 et al. (4 more authors) (2018) Patient-specific coronary blood supply territories for quantitative perfusion analysis. Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization, 6 (2). pp. 137-154. ISSN 2168-1163

Zakkaroff, C orcid.org/0000-0003-3668-8794, Biglands, JD orcid.org/0000-0002-1161-5022, Greenwood, JP orcid.org/0000-0002-2861-0914 et al. (4 more authors) (2018) Patient-specific coronary blood supply territories for quantitative perfusion analysis. Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization, 6 (2). pp. 137-154. ISSN 2168-1163

294004

Rippaus, N, Taggart, D, Williams, J et al. (4 more authors) (2016) Metastatic site-specific polarization of macrophages in intracranial breast cancer metastases. Oncotarget, 7 (27). pp. 41473-41487.

Rippaus, N, Williams, J, Taggart, D et al. (3 more authors) (2016) Dural and parenchymal brain metastases in breast cancer are characterized by distinct inflammatory tumour microenvironments. In: Cancer Research. AACR Special Conference on Tumor Metastasis, 30 Nov - 03 Dec 2016, Austin, Texas, USA. American Association for Cancer Research .

38111

Yin, J, Cohen, R, Jin, Z et al. (16 more authors) (2020) Prognostic and predictive impact of primary tumor sidedness in first-line trials for advanced colorectal cancer: An analysis of 7,828 patients in the ARCAD database. In: 2020 Gastrointestinal Cancers Symposium, 23-25 Jan 2020, San Francisco, California.

Ferraro, DA, Zalcberg, JR, Shi, Q et al. (3 more authors) (2018) Associations of incidence of common adverse events (AEs) and survival outcomes in metastatic colorectal cancer (mCRC) patients (pts) treated with first line chemotherapy: Findings from 9,812 pts in the ARCAD database. In: Journal of Clinical Oncology. 2018 Gastrointestinal Cancers Symposium, 18-20 Jan 2018, San Francisco, CA, USA. American Society of Clinical Oncology .

Selby, P, Liu, L, Downing, A orcid.org/0000-0002-0335-7801 et al. (10 more authors) (2019) How can clinical research improve European health outcomes in cancer? Journal of Cancer Policy, 20. ARTN 100182. ISSN 2213-5383

3M85 approval number 927

Kirby, A orcid.org/0000-0002-2440-9316, Asín-Prieto, E, Burns, FA et al. (7 more authors) (2019) Colo-Pro: a pilot randomised controlled trial to compare standard bolus-dosed cefuroxime prophylaxis to bolus-continuous infusion–dosed cefuroxime prophylaxis for the prevention of infections after colorectal surgery. European Journal of Clinical Microbiology & Infectious Diseases, 38 (2). pp. 357-363. ISSN 0934-9723

Ahmed, S, Bonnett, L, Melhuish, A et al. (50 more authors) (2021) Development of clinical prediction models for outcomes of complicated intra-abdominal infection. British Journal of Surgery. ISSN 0007-1323

Kirby, A orcid.org/0000-0002-2440-9316, Burke, D and Hobson, R (2017) Outcomes After Surgical and Antibiotic Treatment of Appendicitis. World Journal of Surgery, 41 (1). pp. 349-350. ISSN 0364-2313

3T01 - 9203

Ouboussad, L, Wong, C, Hunt, L et al. (3 more authors) (2016) A2.40 Investigating IL-6 pathway signalling kinetics in peripheral blood single cell subsets with tocilizumab therapy in patients with early rheumatoid arthritis. In: Annals of the Rheumatic Diseases. 36th European Workshop for Rheumatology Research, 25-27 Feb 2016, York, UK. BMJ Publishing Group , A31-A31.

3T92/1205

Zakkaroff, C orcid.org/0000-0003-3668-8794, Biglands, JD orcid.org/0000-0002-1161-5022, Greenwood, JP orcid.org/0000-0002-2861-0914 et al. (4 more authors) (2018) Patient-specific coronary blood supply territories for quantitative perfusion analysis. Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization, 6 (2). pp. 137-154. ISSN 2168-1163

4616

Hassanieh, S., Domingo, E., Blake, A. et al. (16 more authors) (2022) 337P Prediction of poor response to oxaliplatin by an RNA signature derived and validated in colorectal cancer clinical trials. In: Annals of Oncology. ESMO Congress 2022, 09-13 Sep 2022, Paris, France. Elsevier , S691.

Seligmann, JF, Domingo, E, Fisher, D et al. (17 more authors) (2022) The clinical relevance of tumor RAS/TP53 dual mutation in early and metastatic colorectal cancer (CRC). In: 2022 ASCO Annual Meeting, 03-07 Jun 2022, Chicago, Il, USA and Online.

Hoorn, ST, Sommeijer, DW, Elliot, F et al. (12 more authors) (2021) Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone. British Journal of Cancer. ISSN 0007-0920

Yin, J, Cohen, R, Jin, Z et al. (16 more authors) (2020) Prognostic and predictive impact of primary tumor sidedness in first-line trials for advanced colorectal cancer: An analysis of 7,828 patients in the ARCAD database. In: 2020 Gastrointestinal Cancers Symposium, 23-25 Jan 2020, San Francisco, California.

Ferraro, DA, Zalcberg, JR, Shi, Q et al. (3 more authors) (2018) Associations of incidence of common adverse events (AEs) and survival outcomes in metastatic colorectal cancer (mCRC) patients (pts) treated with first line chemotherapy: Findings from 9,812 pts in the ARCAD database. In: Journal of Clinical Oncology. 2018 Gastrointestinal Cancers Symposium, 18-20 Jan 2018, San Francisco, CA, USA. American Society of Clinical Oncology .

Selby, P, Liu, L, Downing, A orcid.org/0000-0002-0335-7801 et al. (10 more authors) (2019) How can clinical research improve European health outcomes in cancer? Journal of Cancer Policy, 20. ARTN 100182. ISSN 2213-5383

Hall, PS, Swinson, D, Cairns, DA orcid.org/0000-0002-2338-0179 et al. (32 more authors) (2021) Efficacy of Reduced-Intensity Chemotherapy With Oxaliplatin and Capecitabine on Quality of Life and Cancer Control Among Older and Frail Patients With Advanced Gastroesophageal Cancer: The GO2 Phase 3 Randomized Clinical Trial. JAMA oncology, 7 (6). pp. 869-877. ISSN 2374-2437

Williams, C. orcid.org/0000-0002-1574-653X, Seligmann, J.F. orcid.org/0000-0003-4379-6005, Guetter, C. et al. (13 more authors) (2021) Artificial intelligence-assisted immunohistochemical (IHC) evaluation of tumor amphiregulin (AREG) and epiregulin (EREG) expression as a combined predictive biomarker for panitumumab (Pan) therapy benefit in RAS wild-type (wt) metastatic colorectal cancer (mCRC): Analysis within the phase III PICCOLO trial. In: Journal of Clinical Oncology. 2021 Gastrointestinal Cancers Symposium, 15-17 Jan 2021, Online. American Society of Clinical Oncology , p. 111.

Turnbull, SJ, West, E, Scott, K et al. (3 more authors) (2018) Chemotherapy to reverse diminished immune responses (IRs) associated with a raised neutrophil lymphocyte ratio (NLR) in patients with advanced colorectal cancer (aCRC). In: Journal of Clinical Oncology. American Society of Clinical Oncology, 24 May 2018. American Society of Clinical Oncology .

Platt, JR, Todd, OM orcid.org/0000-0001-7212-8095, Hall, P et al. (14 more authors) (2023) FOxTROT2: innovative trial design to evaluate the role of neoadjuvant chemotherapy for treating locally advanced colon cancer in older adults or those with frailty. ESMO Open, 8 (1). 100642. ISSN 2059-7029

Brown, LC, Graham, J, Fisher, D et al. (15 more authors) (2022) Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer. Clinical Trials, 19 (2). pp. 146-157. ISSN 1740-7745

9/R21/003

Ouboussad, L, Wong, C, Hunt, L et al. (3 more authors) (2016) A2.40 Investigating IL-6 pathway signalling kinetics in peripheral blood single cell subsets with tocilizumab therapy in patients with early rheumatoid arthritis. In: Annals of the Rheumatic Diseases. 36th European Workshop for Rheumatology Research, 25-27 Feb 2016, York, UK. BMJ Publishing Group , A31-A31.

9R01/0004

Platt, JR, Todd, OM orcid.org/0000-0001-7212-8095, Hall, P et al. (14 more authors) (2023) FOxTROT2: innovative trial design to evaluate the role of neoadjuvant chemotherapy for treating locally advanced colon cancer in older adults or those with frailty. ESMO Open, 8 (1). 100642. ISSN 2059-7029

9R01/14-04

Subramanian, V orcid.org/0000-0003-3603-0861, Burr, NE orcid.org/0000-0003-1988-2982 and Hull, MA orcid.org/0000-0001-7414-1576 (2018) Reply: Opioid Toxicity in Inflammatory Bowel Disease Patients Likely Includes Direct Enterocyte Effects That Exacerbate Disease. Clinical Gastroenterology and Hepatology, 16 (10). pp. 1680-1681. ISSN 1542-3565

9R01/14-06

Webster, PJ, Littlejohns, AT, Gaunt, HJ et al. (3 more authors) (2017) AZD1775 Induces Toxicity Through Double-Stranded DNA Breaks Independently of Chemotherapeutic Agents in p53-Mutated Colorectal Cancer Cells. Cell Cycle, 16 (22). pp. 2176-2182. ISSN 1538-4101

Webster, PJ, Littlejohns, AT, Beech, DJ et al. (1 more author) (2017) AZD1775 induces toxicity through double-stranded DNA breaks independent of 5-FU activity in P53 mutated colorectal cancer cells. British Journal of Surgery, 104 (S3). pp. 43-44. ISSN 0007-1323

9R01/14-15

Yiasemidou, M, Glassman, D, Mushtaq, F orcid.org/0000-0001-7881-1127 et al. (4 more authors) (2017) Mental practice with interactive 3D visual aids enhances surgical performance. Surgical Endoscopy, 31 (10). pp. 4111-4117. ISSN 0930-2794

9R01/6002

Ouboussad, L, Wong, C, Hunt, L et al. (3 more authors) (2016) A2.40 Investigating IL-6 pathway signalling kinetics in peripheral blood single cell subsets with tocilizumab therapy in patients with early rheumatoid arthritis. In: Annals of the Rheumatic Diseases. 36th European Workshop for Rheumatology Research, 25-27 Feb 2016, York, UK. BMJ Publishing Group , A31-A31.

9R11-R&D/PP/1112

Shaw, J, Gosein, R, Kalita, MM et al. (19 more authors) (2020) Rationally derived inhibitors of hepatitis C virus (HCV) p7 channel activity reveal prospect for bimodal antiviral therapy. eLife, 9. e52555.

Shaw, J, Gosein, R, Kalita, MM et al. (19 more authors) (2020) Rationally derived inhibitors of hepatitis C virus (HCV) p7 channel activity reveal prospect for bimodal antiviral therapy. eLife, 9. e52555.

9R11/1306

Zagrapan, B, Eilenberg, W, Prausmueller, S et al. (21 more authors) (2019) A Novel Diagnostic and Prognostic Score for Abdominal Aortic Aneurysms Based on D-Dimer and a Comprehensive Analysis of Myeloid Cell Parameters. Thrombosis and Haemostasis, 119 (5). pp. 807-820. ISSN 0340-6245

9R11/14-02

O’Connor, A, Gracie, DJ, Hamlin, PJ et al. (1 more author) (2020) Predictors of Dyspareunia Among Female Patients With Inflammatory Bowel Disease. Clinical Gastroenterology and Hepatology, 18 (4). pp. 1000-1001. ISSN 1542-3565

Gracie, DJ orcid.org/0000-0001-9616-981X, Guthrie, EA orcid.org/0000-0002-5834-6616, Hamlin, PJ et al. (1 more author) (2018) Bi-directionality of Brain-Gut Interactions in Patients With Inflammatory Bowel Disease. Gastroenterology, 154 (6). pp. 1635-1646. ISSN 0016-5085

Hall, BJ, Hamlin, PJ, Gracie, DJ et al. (1 more author) (2018) The Effect of Antidepressants on the Course of Inflammatory Bowel Disease. Canadian Journal of Gastroenterology and Hepatology, 2018. ARTN 2047242. ISSN 2291-2789

Gracie, DJ orcid.org/0000-0001-9616-981X, Hamlin, PJ and Ford, AC orcid.org/0000-0001-6371-4359 (2018) Longitudinal impact of IBS-type symptoms on disease activity, healthcare utilization, psychological health, and quality of life in inflammatory bowel disease. American Journal of Gastroenterology, 113. pp. 702-712. ISSN 0002-9270

9R11/14-08

Watson, H, Cockbain, AJ, Spencer, J et al. (5 more authors) (2016) Measurement of red blood cell eicosapentaenoic acid (EPA) levels in a randomised trial of EPA in patients with colorectal cancer liver metastases. Prostaglandins, Leukotrienes and Essential Fatty Acids, 115. pp. 60-66. ISSN 0952-3278

9R11/14-11

Aldape, K, Amin, SB, Ashley, DM et al. (54 more authors) (2018) Glioma Through the Looking GLASS: Molecular Evolution of Diffuse Gliomas and the Glioma Longitudinal AnalySiS Consortium. Neuro-Oncology, 20 (7). pp. 873-884. ISSN 1522-8517

Tanner, G., Barrow, R., Ajaib, S. et al. (27 more authors) (2024) IDHwt glioblastomas can be stratified by their transcriptional response to standard treatment, with implications for targeted therapy. Genome Biology, 25. 45. ISSN 1474-760X

Tanner, G., Finetti, M.A., Pollock, S. et al. (13 more authors) (2022) IDHwt Glioblastomas Show Opposing Resistance Mechanisms Across Patients in Response to Standard Treatment. In: BNOS 2022, 22-24 Jun 2022, Liverpool.

Varn, F.S., Johnson, K.C., Martinek, J. et al. (39 more authors) (2022) Longitudinal analysis of diffuse glioma reveals cell state dynamics at recurrence associated with changes in genetics and the microenvironment. In: American Association for Cancer Research Annual Meeting 2022, 08-13 Apr 2022, Philadelphia.

Droop, A orcid.org/0000-0001-7695-7480, Bruns, A orcid.org/0000-0002-6970-4036, Tanner, G et al. (12 more authors) (2018) How to analyse the spatiotemporal tumour samples needed to investigate cancer evolution: A case study using paired primary and recurrent glioblastoma. International Journal of Cancer, 142 (8). pp. 1620-1626. ISSN 0020-7136

Barthel, F, Johnson, KC, Frederick Jr, V et al. (10 more authors) (2019) GENE-28. Longitudinal Molecular Trajectories of Diffuse Glioma in Adults. In: 24th Annual Scientific Meeting and Education Day of the Society for Neuro-Oncology, 20-24 Nov 2019, Phoenix, Arizona, USA.

Barthel, FP, Johnson, KC, Varn, FS et al. (86 more authors) (2019) Longitudinal Molecular Trajectories of Diffuse Glioma in Adults. Nature, 576. pp. 112-120. ISSN 0028-0836

Bruns, A-F, Rippaus, N, Droop, A et al. (8 more authors) (2019) Chromatin remodelling to facilitate treatment resistance in glioblastoma. In: British Neuro-Oncology Society Annual Meeting 2019 (BNOS 2019), 03-05 Jul 2019, London, UK.

Rippaus, N, Manning, J, Droop, A et al. (9 more authors) (2019) OS9.5 Evidence that adult glioblastoma adapts to standard therapy though chromatin remodeling. In: 14th Meeting of the European Association of Neuro-Oncology, 19-22 Sep 2019, Lyon, France.

9R11/6002

Ouboussad, L, Wong, C, Hunt, L et al. (3 more authors) (2016) A2.40 Investigating IL-6 pathway signalling kinetics in peripheral blood single cell subsets with tocilizumab therapy in patients with early rheumatoid arthritis. In: Annals of the Rheumatic Diseases. 36th European Workshop for Rheumatology Research, 25-27 Feb 2016, York, UK. BMJ Publishing Group , A31-A31.

9R11/8001

Foley, JRJ, Swoboda, PP orcid.org/0000-0001-7162-7079, Fent, GJ et al. (9 more authors) (2018) Quantitative deformation analysis differentiates ischaemic and non-ischaemic cardiomyopathy: sub-group analysis of the VINDICATE trial. European Heart Journal - Cardiovascular Imaging, 19 (7). pp. 816-823. ISSN 2047-2404

9R11/8006

Ouboussad, L, Wong, C, Hunt, L et al. (3 more authors) (2016) A2.40 Investigating IL-6 pathway signalling kinetics in peripheral blood single cell subsets with tocilizumab therapy in patients with early rheumatoid arthritis. In: Annals of the Rheumatic Diseases. 36th European Workshop for Rheumatology Research, 25-27 Feb 2016, York, UK. BMJ Publishing Group , A31-A31.

9R11/8007

Robinson, JI orcid.org/0000-0001-5425-7520, Md Yusof, MY orcid.org/0000-0003-3131-9121, Davies, V et al. (20 more authors) (2022) Comprehensive genetic and functional analyses of Fc gamma receptors influence on response to rituximab therapy for autoimmunity. eBioMedicine, 86. 104343. ISSN 2352-3964

A14923

Yin, J, Cohen, R, Jin, Z et al. (16 more authors) (2020) Prognostic and predictive impact of primary tumor sidedness in first-line trials for advanced colorectal cancer: An analysis of 7,828 patients in the ARCAD database. In: 2020 Gastrointestinal Cancers Symposium, 23-25 Jan 2020, San Francisco, California.

Hall, P, Swinson, D, Lord, S et al. (23 more authors) (2019) Optimizing Chemotherapy for Frail and Elderly Patients with Advanced Gastroesophageal Cancer (aGOAC): the GO2 Phase III Trial. In: 2019 NCRI Cancer Conference of National Cancer Research Institute, 03-05 Nov 2019, Glasgow, Scotland, UK.

Hall, PS, Swinson, D, Cairns, DA orcid.org/0000-0002-2338-0179 et al. (32 more authors) (2021) Efficacy of Reduced-Intensity Chemotherapy With Oxaliplatin and Capecitabine on Quality of Life and Cancer Control Among Older and Frail Patients With Advanced Gastroesophageal Cancer: The GO2 Phase 3 Randomized Clinical Trial. JAMA oncology, 7 (6). pp. 869-877. ISSN 2374-2437

Platt, JR, Todd, OM orcid.org/0000-0001-7212-8095, Hall, P et al. (14 more authors) (2023) FOxTROT2: innovative trial design to evaluate the role of neoadjuvant chemotherapy for treating locally advanced colon cancer in older adults or those with frailty. ESMO Open, 8 (1). 100642. ISSN 2059-7029

A17859

Lee, RW, Danson, S, Elliot, M et al. (8 more authors) (2022) Importance of clinical research for the UK's 10-year cancer plan. The Lancet Oncology. ISSN 1470-2045

A24939

Yin, J, Cohen, R, Jin, Z et al. (16 more authors) (2020) Prognostic and predictive impact of primary tumor sidedness in first-line trials for advanced colorectal cancer: An analysis of 7,828 patients in the ARCAD database. In: 2020 Gastrointestinal Cancers Symposium, 23-25 Jan 2020, San Francisco, California.

Selby, P, Liu, L, Downing, A orcid.org/0000-0002-0335-7801 et al. (10 more authors) (2019) How can clinical research improve European health outcomes in cancer? Journal of Cancer Policy, 20. ARTN 100182. ISSN 2213-5383

C28106/A9844

Lee, RW, Danson, S, Elliot, M et al. (8 more authors) (2022) Importance of clinical research for the UK's 10-year cancer plan. The Lancet Oncology. ISSN 1470-2045

C588/A4994

Ferraro, DA, Zalcberg, JR, Shi, Q et al. (3 more authors) (2018) Associations of incidence of common adverse events (AEs) and survival outcomes in metastatic colorectal cancer (mCRC) patients (pts) treated with first line chemotherapy: Findings from 9,812 pts in the ARCAD database. In: Journal of Clinical Oncology. 2018 Gastrointestinal Cancers Symposium, 18-20 Jan 2018, San Francisco, CA, USA. American Society of Clinical Oncology .

Ferraro, DA, Zalcberg, JR, Shi, Q et al. (3 more authors) (2018) Associations of incidence of common adverse events (AEs) and survival outcomes in metastatic colorectal cancer (mCRC) patients (pts) treated with first line chemotherapy: Findings from 9,812 pts in the ARCAD database. In: Journal of Clinical Oncology. 2018 Gastrointestinal Cancers Symposium, 18-20 Jan 2018, San Francisco, CA, USA. American Society of Clinical Oncology .

Selby, P, Liu, L, Downing, A orcid.org/0000-0002-0335-7801 et al. (10 more authors) (2019) How can clinical research improve European health outcomes in cancer? Journal of Cancer Policy, 20. ARTN 100182. ISSN 2213-5383

Selby, P, Liu, L, Downing, A orcid.org/0000-0002-0335-7801 et al. (10 more authors) (2019) How can clinical research improve European health outcomes in cancer? Journal of Cancer Policy, 20. ARTN 100182. ISSN 2213-5383

C6003/A10079

Hall, P, Swinson, D, Lord, S et al. (23 more authors) (2019) Optimizing Chemotherapy for Frail and Elderly Patients with Advanced Gastroesophageal Cancer (aGOAC): the GO2 Phase III Trial. In: 2019 NCRI Cancer Conference of National Cancer Research Institute, 03-05 Nov 2019, Glasgow, Scotland, UK.

Hall, PS, Swinson, D, Cairns, DA orcid.org/0000-0002-2338-0179 et al. (32 more authors) (2021) Efficacy of Reduced-Intensity Chemotherapy With Oxaliplatin and Capecitabine on Quality of Life and Cancer Control Among Older and Frail Patients With Advanced Gastroesophageal Cancer: The GO2 Phase 3 Randomized Clinical Trial. JAMA oncology, 7 (6). pp. 869-877. ISSN 2374-2437

Platt, JR, Todd, OM orcid.org/0000-0001-7212-8095, Hall, P et al. (14 more authors) (2023) FOxTROT2: innovative trial design to evaluate the role of neoadjuvant chemotherapy for treating locally advanced colon cancer in older adults or those with frailty. ESMO Open, 8 (1). 100642. ISSN 2059-7029

C6003/A15546

Seligmann, JF, Domingo, E, Fisher, D et al. (17 more authors) (2022) The clinical relevance of tumor RAS/TP53 dual mutation in early and metastatic colorectal cancer (CRC). In: 2022 ASCO Annual Meeting, 03-07 Jun 2022, Chicago, Il, USA and Online.

Hoorn, ST, Sommeijer, DW, Elliot, F et al. (12 more authors) (2021) Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone. British Journal of Cancer. ISSN 0007-0920

Williams, C. orcid.org/0000-0002-1574-653X, Seligmann, J.F. orcid.org/0000-0003-4379-6005, Guetter, C. et al. (13 more authors) (2021) Artificial intelligence-assisted immunohistochemical (IHC) evaluation of tumor amphiregulin (AREG) and epiregulin (EREG) expression as a combined predictive biomarker for panitumumab (Pan) therapy benefit in RAS wild-type (wt) metastatic colorectal cancer (mCRC): Analysis within the phase III PICCOLO trial. In: Journal of Clinical Oncology. 2021 Gastrointestinal Cancers Symposium, 15-17 Jan 2021, Online. American Society of Clinical Oncology , p. 111.

C6003/A3830

Hassanieh, S., Domingo, E., Blake, A. et al. (16 more authors) (2022) 337P Prediction of poor response to oxaliplatin by an RNA signature derived and validated in colorectal cancer clinical trials. In: Annals of Oncology. ESMO Congress 2022, 09-13 Sep 2022, Paris, France. Elsevier , S691.

Yin, J, Cohen, R, Jin, Z et al. (16 more authors) (2020) Prognostic and predictive impact of primary tumor sidedness in first-line trials for advanced colorectal cancer: An analysis of 7,828 patients in the ARCAD database. In: 2020 Gastrointestinal Cancers Symposium, 23-25 Jan 2020, San Francisco, California.

Ferraro, DA, Zalcberg, JR, Shi, Q et al. (3 more authors) (2018) Associations of incidence of common adverse events (AEs) and survival outcomes in metastatic colorectal cancer (mCRC) patients (pts) treated with first line chemotherapy: Findings from 9,812 pts in the ARCAD database. In: Journal of Clinical Oncology. 2018 Gastrointestinal Cancers Symposium, 18-20 Jan 2018, San Francisco, CA, USA. American Society of Clinical Oncology .

Hall, P, Swinson, D, Lord, S et al. (23 more authors) (2019) Optimizing Chemotherapy for Frail and Elderly Patients with Advanced Gastroesophageal Cancer (aGOAC): the GO2 Phase III Trial. In: 2019 NCRI Cancer Conference of National Cancer Research Institute, 03-05 Nov 2019, Glasgow, Scotland, UK.

Platt, JR, Todd, OM orcid.org/0000-0001-7212-8095, Hall, P et al. (14 more authors) (2023) FOxTROT2: innovative trial design to evaluate the role of neoadjuvant chemotherapy for treating locally advanced colon cancer in older adults or those with frailty. ESMO Open, 8 (1). 100642. ISSN 2059-7029

C6003/A6407

Hoorn, ST, Sommeijer, DW, Elliot, F et al. (12 more authors) (2021) Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone. British Journal of Cancer. ISSN 0007-0920

Hoorn, ST, Sommeijer, DW, Elliot, F et al. (12 more authors) (2021) Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone. British Journal of Cancer. ISSN 0007-0920

Yin, J, Cohen, R, Jin, Z et al. (16 more authors) (2020) Prognostic and predictive impact of primary tumor sidedness in first-line trials for advanced colorectal cancer: An analysis of 7,828 patients in the ARCAD database. In: 2020 Gastrointestinal Cancers Symposium, 23-25 Jan 2020, San Francisco, California.

Yin, J, Cohen, R, Jin, Z et al. (16 more authors) (2020) Prognostic and predictive impact of primary tumor sidedness in first-line trials for advanced colorectal cancer: An analysis of 7,828 patients in the ARCAD database. In: 2020 Gastrointestinal Cancers Symposium, 23-25 Jan 2020, San Francisco, California.

Ferraro, DA, Zalcberg, JR, Shi, Q et al. (3 more authors) (2018) Associations of incidence of common adverse events (AEs) and survival outcomes in metastatic colorectal cancer (mCRC) patients (pts) treated with first line chemotherapy: Findings from 9,812 pts in the ARCAD database. In: Journal of Clinical Oncology. 2018 Gastrointestinal Cancers Symposium, 18-20 Jan 2018, San Francisco, CA, USA. American Society of Clinical Oncology .

Williams, C. orcid.org/0000-0002-1574-653X, Seligmann, J.F. orcid.org/0000-0003-4379-6005, Guetter, C. et al. (13 more authors) (2021) Artificial intelligence-assisted immunohistochemical (IHC) evaluation of tumor amphiregulin (AREG) and epiregulin (EREG) expression as a combined predictive biomarker for panitumumab (Pan) therapy benefit in RAS wild-type (wt) metastatic colorectal cancer (mCRC): Analysis within the phase III PICCOLO trial. In: Journal of Clinical Oncology. 2021 Gastrointestinal Cancers Symposium, 15-17 Jan 2021, Online. American Society of Clinical Oncology , p. 111.

Williams, C. orcid.org/0000-0002-1574-653X, Seligmann, J.F. orcid.org/0000-0003-4379-6005, Guetter, C. et al. (13 more authors) (2021) Artificial intelligence-assisted immunohistochemical (IHC) evaluation of tumor amphiregulin (AREG) and epiregulin (EREG) expression as a combined predictive biomarker for panitumumab (Pan) therapy benefit in RAS wild-type (wt) metastatic colorectal cancer (mCRC): Analysis within the phase III PICCOLO trial. In: Journal of Clinical Oncology. 2021 Gastrointestinal Cancers Symposium, 15-17 Jan 2021, Online. American Society of Clinical Oncology , p. 111.

C6003/A7367

Hassanieh, S., Domingo, E., Blake, A. et al. (16 more authors) (2022) 337P Prediction of poor response to oxaliplatin by an RNA signature derived and validated in colorectal cancer clinical trials. In: Annals of Oncology. ESMO Congress 2022, 09-13 Sep 2022, Paris, France. Elsevier , S691.

Seligmann, JF, Domingo, E, Fisher, D et al. (17 more authors) (2022) The clinical relevance of tumor RAS/TP53 dual mutation in early and metastatic colorectal cancer (CRC). In: 2022 ASCO Annual Meeting, 03-07 Jun 2022, Chicago, Il, USA and Online.

Hoorn, ST, Sommeijer, DW, Elliot, F et al. (12 more authors) (2021) Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone. British Journal of Cancer. ISSN 0007-0920

Yin, J, Cohen, R, Jin, Z et al. (16 more authors) (2020) Prognostic and predictive impact of primary tumor sidedness in first-line trials for advanced colorectal cancer: An analysis of 7,828 patients in the ARCAD database. In: 2020 Gastrointestinal Cancers Symposium, 23-25 Jan 2020, San Francisco, California.

Williams, C. orcid.org/0000-0002-1574-653X, Seligmann, J.F. orcid.org/0000-0003-4379-6005, Guetter, C. et al. (13 more authors) (2021) Artificial intelligence-assisted immunohistochemical (IHC) evaluation of tumor amphiregulin (AREG) and epiregulin (EREG) expression as a combined predictive biomarker for panitumumab (Pan) therapy benefit in RAS wild-type (wt) metastatic colorectal cancer (mCRC): Analysis within the phase III PICCOLO trial. In: Journal of Clinical Oncology. 2021 Gastrointestinal Cancers Symposium, 15-17 Jan 2021, Online. American Society of Clinical Oncology , p. 111.

C6003/A7686

Hoorn, ST, Sommeijer, DW, Elliot, F et al. (12 more authors) (2021) Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone. British Journal of Cancer. ISSN 0007-0920

Ferraro, DA, Zalcberg, JR, Shi, Q et al. (3 more authors) (2018) Associations of incidence of common adverse events (AEs) and survival outcomes in metastatic colorectal cancer (mCRC) patients (pts) treated with first line chemotherapy: Findings from 9,812 pts in the ARCAD database. In: Journal of Clinical Oncology. 2018 Gastrointestinal Cancers Symposium, 18-20 Jan 2018, San Francisco, CA, USA. American Society of Clinical Oncology .

Selby, P, Liu, L, Downing, A orcid.org/0000-0002-0335-7801 et al. (10 more authors) (2019) How can clinical research improve European health outcomes in cancer? Journal of Cancer Policy, 20. ARTN 100182. ISSN 2213-5383

Platt, JR, Todd, OM orcid.org/0000-0001-7212-8095, Hall, P et al. (14 more authors) (2023) FOxTROT2: innovative trial design to evaluate the role of neoadjuvant chemotherapy for treating locally advanced colon cancer in older adults or those with frailty. ESMO Open, 8 (1). 100642. ISSN 2059-7029

C7852/A19772

Hassanieh, S., Domingo, E., Blake, A. et al. (16 more authors) (2022) 337P Prediction of poor response to oxaliplatin by an RNA signature derived and validated in colorectal cancer clinical trials. In: Annals of Oncology. ESMO Congress 2022, 09-13 Sep 2022, Paris, France. Elsevier , S691.

Seligmann, JF, Domingo, E, Fisher, D et al. (17 more authors) (2022) The clinical relevance of tumor RAS/TP53 dual mutation in early and metastatic colorectal cancer (CRC). In: 2022 ASCO Annual Meeting, 03-07 Jun 2022, Chicago, Il, USA and Online.

Hoorn, ST, Sommeijer, DW, Elliot, F et al. (12 more authors) (2021) Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone. British Journal of Cancer. ISSN 0007-0920

Williams, C. orcid.org/0000-0002-1574-653X, Seligmann, J.F. orcid.org/0000-0003-4379-6005, Guetter, C. et al. (13 more authors) (2021) Artificial intelligence-assisted immunohistochemical (IHC) evaluation of tumor amphiregulin (AREG) and epiregulin (EREG) expression as a combined predictive biomarker for panitumumab (Pan) therapy benefit in RAS wild-type (wt) metastatic colorectal cancer (mCRC): Analysis within the phase III PICCOLO trial. In: Journal of Clinical Oncology. 2021 Gastrointestinal Cancers Symposium, 15-17 Jan 2021, Online. American Society of Clinical Oncology , p. 111.

Turnbull, SJ, West, E, Scott, K et al. (3 more authors) (2018) Chemotherapy to reverse diminished immune responses (IRs) associated with a raised neutrophil lymphocyte ratio (NLR) in patients with advanced colorectal cancer (aCRC). In: Journal of Clinical Oncology. American Society of Clinical Oncology, 24 May 2018. American Society of Clinical Oncology .

Platt, JR, Todd, OM orcid.org/0000-0001-7212-8095, Hall, P et al. (14 more authors) (2023) FOxTROT2: innovative trial design to evaluate the role of neoadjuvant chemotherapy for treating locally advanced colon cancer in older adults or those with frailty. ESMO Open, 8 (1). 100642. ISSN 2059-7029

Brown, LC, Graham, J, Fisher, D et al. (15 more authors) (2022) Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer. Clinical Trials, 19 (2). pp. 146-157. ISSN 1740-7745

CH/16/2/32089

Zakkaroff, C orcid.org/0000-0003-3668-8794, Biglands, JD orcid.org/0000-0002-1161-5022, Greenwood, JP orcid.org/0000-0002-2861-0914 et al. (4 more authors) (2018) Patient-specific coronary blood supply territories for quantitative perfusion analysis. Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization, 6 (2). pp. 137-154. ISSN 2168-1163

CRUK 04 05 BUDGET

Yin, J, Cohen, R, Jin, Z et al. (16 more authors) (2020) Prognostic and predictive impact of primary tumor sidedness in first-line trials for advanced colorectal cancer: An analysis of 7,828 patients in the ARCAD database. In: 2020 Gastrointestinal Cancers Symposium, 23-25 Jan 2020, San Francisco, California.

Ferraro, DA, Zalcberg, JR, Shi, Q et al. (3 more authors) (2018) Associations of incidence of common adverse events (AEs) and survival outcomes in metastatic colorectal cancer (mCRC) patients (pts) treated with first line chemotherapy: Findings from 9,812 pts in the ARCAD database. In: Journal of Clinical Oncology. 2018 Gastrointestinal Cancers Symposium, 18-20 Jan 2018, San Francisco, CA, USA. American Society of Clinical Oncology .

Selby, P, Liu, L, Downing, A orcid.org/0000-0002-0335-7801 et al. (10 more authors) (2019) How can clinical research improve European health outcomes in cancer? Journal of Cancer Policy, 20. ARTN 100182. ISSN 2213-5383

CRUK 05 06 BUDGET

Yin, J, Cohen, R, Jin, Z et al. (16 more authors) (2020) Prognostic and predictive impact of primary tumor sidedness in first-line trials for advanced colorectal cancer: An analysis of 7,828 patients in the ARCAD database. In: 2020 Gastrointestinal Cancers Symposium, 23-25 Jan 2020, San Francisco, California.

Ferraro, DA, Zalcberg, JR, Shi, Q et al. (3 more authors) (2018) Associations of incidence of common adverse events (AEs) and survival outcomes in metastatic colorectal cancer (mCRC) patients (pts) treated with first line chemotherapy: Findings from 9,812 pts in the ARCAD database. In: Journal of Clinical Oncology. 2018 Gastrointestinal Cancers Symposium, 18-20 Jan 2018, San Francisco, CA, USA. American Society of Clinical Oncology .

Ferraro, DA, Zalcberg, JR, Shi, Q et al. (3 more authors) (2018) Associations of incidence of common adverse events (AEs) and survival outcomes in metastatic colorectal cancer (mCRC) patients (pts) treated with first line chemotherapy: Findings from 9,812 pts in the ARCAD database. In: Journal of Clinical Oncology. 2018 Gastrointestinal Cancers Symposium, 18-20 Jan 2018, San Francisco, CA, USA. American Society of Clinical Oncology .

Ferraro, DA, Zalcberg, JR, Shi, Q et al. (3 more authors) (2018) Associations of incidence of common adverse events (AEs) and survival outcomes in metastatic colorectal cancer (mCRC) patients (pts) treated with first line chemotherapy: Findings from 9,812 pts in the ARCAD database. In: Journal of Clinical Oncology. 2018 Gastrointestinal Cancers Symposium, 18-20 Jan 2018, San Francisco, CA, USA. American Society of Clinical Oncology .

Selby, P, Liu, L, Downing, A orcid.org/0000-0002-0335-7801 et al. (10 more authors) (2019) How can clinical research improve European health outcomes in cancer? Journal of Cancer Policy, 20. ARTN 100182. ISSN 2213-5383

Selby, P, Liu, L, Downing, A orcid.org/0000-0002-0335-7801 et al. (10 more authors) (2019) How can clinical research improve European health outcomes in cancer? Journal of Cancer Policy, 20. ARTN 100182. ISSN 2213-5383

Platt, JR, Todd, OM orcid.org/0000-0001-7212-8095, Hall, P et al. (14 more authors) (2023) FOxTROT2: innovative trial design to evaluate the role of neoadjuvant chemotherapy for treating locally advanced colon cancer in older adults or those with frailty. ESMO Open, 8 (1). 100642. ISSN 2059-7029

CS-2013-13-032

Robinson, JI orcid.org/0000-0001-5425-7520, Md Yusof, MY orcid.org/0000-0003-3131-9121, Davies, V et al. (20 more authors) (2022) Comprehensive genetic and functional analyses of Fc gamma receptors influence on response to rituximab therapy for autoimmunity. eBioMedicine, 86. 104343. ISSN 2352-3964

DRF-2014-07-155

Robinson, JI orcid.org/0000-0001-5425-7520, Md Yusof, MY orcid.org/0000-0003-3131-9121, Davies, V et al. (20 more authors) (2022) Comprehensive genetic and functional analyses of Fc gamma receptors influence on response to rituximab therapy for autoimmunity. eBioMedicine, 86. 104343. ISSN 2352-3964

FA/13/23/30122

Webster, PJ, Littlejohns, AT, Gaunt, HJ et al. (3 more authors) (2017) AZD1775 Induces Toxicity Through Double-Stranded DNA Breaks Independently of Chemotherapeutic Agents in p53-Mutated Colorectal Cancer Cells. Cell Cycle, 16 (22). pp. 2176-2182. ISSN 1538-4101

FS/14/22/30734 - H Gaunt

Webster, PJ, Littlejohns, AT, Gaunt, HJ et al. (3 more authors) (2017) AZD1775 Induces Toxicity Through Double-Stranded DNA Breaks Independently of Chemotherapeutic Agents in p53-Mutated Colorectal Cancer Cells. Cell Cycle, 16 (22). pp. 2176-2182. ISSN 1538-4101

FS/18/12/33270

Zagrapan, B, Eilenberg, W, Prausmueller, S et al. (21 more authors) (2019) A Novel Diagnostic and Prognostic Score for Abdominal Aortic Aneurysms Based on D-Dimer and a Comprehensive Analysis of Myeloid Cell Parameters. Thrombosis and Haemostasis, 119 (5). pp. 807-820. ISSN 0340-6245

FUND NUMBER 1T04

Thorne, JL orcid.org/0000-0002-3037-8528, Battaglia, S, Baxter, DE orcid.org/0000-0001-8830-6802 et al. (8 more authors) (2018) MiR-19b non-canonical binding is directed by HuR and confers chemosensitivity through regulation of P-glycoprotein in breast cancer. BBA - Gene Regulatory Mechanisms, 1861 (11). pp. 996-1006. ISSN 1874-9399

Fund No IT01

Seligmann, JF, Domingo, E, Fisher, D et al. (17 more authors) (2022) The clinical relevance of tumor RAS/TP53 dual mutation in early and metastatic colorectal cancer (CRC). In: 2022 ASCO Annual Meeting, 03-07 Jun 2022, Chicago, Il, USA and Online.

Hoorn, ST, Sommeijer, DW, Elliot, F et al. (12 more authors) (2021) Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone. British Journal of Cancer. ISSN 0007-0920

Hall, P, Swinson, D, Lord, S et al. (23 more authors) (2019) Optimizing Chemotherapy for Frail and Elderly Patients with Advanced Gastroesophageal Cancer (aGOAC): the GO2 Phase III Trial. In: 2019 NCRI Cancer Conference of National Cancer Research Institute, 03-05 Nov 2019, Glasgow, Scotland, UK.

Turnbull, SJ, West, E, Scott, K et al. (3 more authors) (2018) Chemotherapy to reverse diminished immune responses (IRs) associated with a raised neutrophil lymphocyte ratio (NLR) in patients with advanced colorectal cancer (aCRC). In: Journal of Clinical Oncology. American Society of Clinical Oncology, 24 May 2018. American Society of Clinical Oncology .

Platt, JR, Todd, OM orcid.org/0000-0001-7212-8095, Hall, P et al. (14 more authors) (2023) FOxTROT2: innovative trial design to evaluate the role of neoadjuvant chemotherapy for treating locally advanced colon cancer in older adults or those with frailty. ESMO Open, 8 (1). 100642. ISSN 2059-7029

Brown, LC, Graham, J, Fisher, D et al. (15 more authors) (2022) Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer. Clinical Trials, 19 (2). pp. 146-157. ISSN 1740-7745

Lee, RW, Danson, S, Elliot, M et al. (8 more authors) (2022) Importance of clinical research for the UK's 10-year cancer plan. The Lancet Oncology. ISSN 1470-2045

G0700124 ID 81396

Shaw, J, Gosein, R, Kalita, MM et al. (19 more authors) (2020) Rationally derived inhibitors of hepatitis C virus (HCV) p7 channel activity reveal prospect for bimodal antiviral therapy. eLife, 9. e52555.

G1001518

Ouboussad, L, Wong, C, Hunt, L et al. (3 more authors) (2016) A2.40 Investigating IL-6 pathway signalling kinetics in peripheral blood single cell subsets with tocilizumab therapy in patients with early rheumatoid arthritis. In: Annals of the Rheumatic Diseases. 36th European Workshop for Rheumatology Research, 25-27 Feb 2016, York, UK. BMJ Publishing Group , A31-A31.

Ouboussad, L, Wong, C, Hunt, L et al. (3 more authors) (2016) A2.40 Investigating IL-6 pathway signalling kinetics in peripheral blood single cell subsets with tocilizumab therapy in patients with early rheumatoid arthritis. In: Annals of the Rheumatic Diseases. 36th European Workshop for Rheumatology Research, 25-27 Feb 2016, York, UK. BMJ Publishing Group , A31-A31.

G1002076/1

Webster, PJ, Littlejohns, AT, Gaunt, HJ et al. (3 more authors) (2017) AZD1775 Induces Toxicity Through Double-Stranded DNA Breaks Independently of Chemotherapeutic Agents in p53-Mutated Colorectal Cancer Cells. Cell Cycle, 16 (22). pp. 2176-2182. ISSN 1538-4101

IE160146

Thorne, JL orcid.org/0000-0002-3037-8528, Battaglia, S, Baxter, DE orcid.org/0000-0001-8830-6802 et al. (8 more authors) (2018) MiR-19b non-canonical binding is directed by HuR and confers chemosensitivity through regulation of P-glycoprotein in breast cancer. BBA - Gene Regulatory Mechanisms, 1861 (11). pp. 996-1006. ISSN 1874-9399

L004PhD

Rippaus, N, Williams, J, Taggart, D et al. (3 more authors) (2016) Dural and parenchymal brain metastases in breast cancer are characterized by distinct inflammatory tumour microenvironments. In: Cancer Research. AACR Special Conference on Tumor Metastasis, 30 Nov - 03 Dec 2016, Austin, Texas, USA. American Association for Cancer Research .

L368

Watson, H, Cockbain, AJ, Spencer, J et al. (5 more authors) (2016) Measurement of red blood cell eicosapentaenoic acid (EPA) levels in a randomised trial of EPA in patients with colorectal cancer liver metastases. Prostaglandins, Leukotrienes and Essential Fatty Acids, 115. pp. 60-66. ISSN 0952-3278

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Turnbull, SJ, West, E, Scott, K et al. (3 more authors) (2018) Chemotherapy to reverse diminished immune responses (IRs) associated with a raised neutrophil lymphocyte ratio (NLR) in patients with advanced colorectal cancer (aCRC). In: Journal of Clinical Oncology. American Society of Clinical Oncology, 24 May 2018. American Society of Clinical Oncology .

Platt, JR, Todd, OM orcid.org/0000-0001-7212-8095, Hall, P et al. (14 more authors) (2023) FOxTROT2: innovative trial design to evaluate the role of neoadjuvant chemotherapy for treating locally advanced colon cancer in older adults or those with frailty. ESMO Open, 8 (1). 100642. ISSN 2059-7029

Brown, LC, Graham, J, Fisher, D et al. (15 more authors) (2022) Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer. Clinical Trials, 19 (2). pp. 146-157. ISSN 1740-7745

Lee, RW, Danson, S, Elliot, M et al. (8 more authors) (2022) Importance of clinical research for the UK's 10-year cancer plan. The Lancet Oncology. ISSN 1470-2045

L394

Brown, LC, Graham, J, Fisher, D et al. (15 more authors) (2022) Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer. Clinical Trials, 19 (2). pp. 146-157. ISSN 1740-7745

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Platt, JR, Todd, OM orcid.org/0000-0001-7212-8095, Hall, P et al. (14 more authors) (2023) FOxTROT2: innovative trial design to evaluate the role of neoadjuvant chemotherapy for treating locally advanced colon cancer in older adults or those with frailty. ESMO Open, 8 (1). 100642. ISSN 2059-7029

LMBRU

Ouboussad, L, Wong, C, Hunt, L et al. (3 more authors) (2016) A2.40 Investigating IL-6 pathway signalling kinetics in peripheral blood single cell subsets with tocilizumab therapy in patients with early rheumatoid arthritis. In: Annals of the Rheumatic Diseases. 36th European Workshop for Rheumatology Research, 25-27 Feb 2016, York, UK. BMJ Publishing Group , A31-A31.

LPP043

Rippaus, N, Taggart, D, Williams, J et al. (4 more authors) (2016) Metastatic site-specific polarization of macrophages in intracranial breast cancer metastases. Oncotarget, 7 (27). pp. 41473-41487.

Rippaus, N, Williams, J, Taggart, D et al. (3 more authors) (2016) Dural and parenchymal brain metastases in breast cancer are characterized by distinct inflammatory tumour microenvironments. In: Cancer Research. AACR Special Conference on Tumor Metastasis, 30 Nov - 03 Dec 2016, Austin, Texas, USA. American Association for Cancer Research .

LPP072

Bruns, A-F, Rippaus, N, Droop, A et al. (8 more authors) (2019) Chromatin remodelling to facilitate treatment resistance in glioblastoma. In: British Neuro-Oncology Society Annual Meeting 2019 (BNOS 2019), 03-05 Jul 2019, London, UK.

Rippaus, N, Manning, J, Droop, A et al. (9 more authors) (2019) OS9.5 Evidence that adult glioblastoma adapts to standard therapy though chromatin remodeling. In: 14th Meeting of the European Association of Neuro-Oncology, 19-22 Sep 2019, Lyon, France.

M SPRAKES

Ouboussad, L, Wong, C, Hunt, L et al. (3 more authors) (2016) A2.40 Investigating IL-6 pathway signalling kinetics in peripheral blood single cell subsets with tocilizumab therapy in patients with early rheumatoid arthritis. In: Annals of the Rheumatic Diseases. 36th European Workshop for Rheumatology Research, 25-27 Feb 2016, York, UK. BMJ Publishing Group , A31-A31.

M0653

Robinson, JI orcid.org/0000-0001-5425-7520, Md Yusof, MY orcid.org/0000-0003-3131-9121, Davies, V et al. (20 more authors) (2022) Comprehensive genetic and functional analyses of Fc gamma receptors influence on response to rituximab therapy for autoimmunity. eBioMedicine, 86. 104343. ISSN 2352-3964

MC_PC_13066

Shaw, J, Gosein, R, Kalita, MM et al. (19 more authors) (2020) Rationally derived inhibitors of hepatitis C virus (HCV) p7 channel activity reveal prospect for bimodal antiviral therapy. eLife, 9. e52555.

MP/19269

Ouboussad, L, Wong, C, Hunt, L et al. (3 more authors) (2016) A2.40 Investigating IL-6 pathway signalling kinetics in peripheral blood single cell subsets with tocilizumab therapy in patients with early rheumatoid arthritis. In: Annals of the Rheumatic Diseases. 36th European Workshop for Rheumatology Research, 25-27 Feb 2016, York, UK. BMJ Publishing Group , A31-A31.

MR/J00281X/1

Foley, JRJ, Swoboda, PP orcid.org/0000-0001-7162-7079, Fent, GJ et al. (9 more authors) (2018) Quantitative deformation analysis differentiates ischaemic and non-ischaemic cardiomyopathy: sub-group analysis of the VINDICATE trial. European Heart Journal - Cardiovascular Imaging, 19 (7). pp. 816-823. ISSN 2047-2404

MR/L01629X/1

Droop, A orcid.org/0000-0001-7695-7480, Bruns, A orcid.org/0000-0002-6970-4036, Tanner, G et al. (12 more authors) (2018) How to analyse the spatiotemporal tumour samples needed to investigate cancer evolution: A case study using paired primary and recurrent glioblastoma. International Journal of Cancer, 142 (8). pp. 1620-1626. ISSN 0020-7136

MR/M016587/1

Yin, J, Cohen, R, Jin, Z et al. (16 more authors) (2020) Prognostic and predictive impact of primary tumor sidedness in first-line trials for advanced colorectal cancer: An analysis of 7,828 patients in the ARCAD database. In: 2020 Gastrointestinal Cancers Symposium, 23-25 Jan 2020, San Francisco, California.

Platt, JR, Todd, OM orcid.org/0000-0001-7212-8095, Hall, P et al. (14 more authors) (2023) FOxTROT2: innovative trial design to evaluate the role of neoadjuvant chemotherapy for treating locally advanced colon cancer in older adults or those with frailty. ESMO Open, 8 (1). 100642. ISSN 2059-7029

Brown, LC, Graham, J, Fisher, D et al. (15 more authors) (2022) Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer. Clinical Trials, 19 (2). pp. 146-157. ISSN 1740-7745

MR/M01665X/1 - R118193

Robinson, JI orcid.org/0000-0001-5425-7520, Md Yusof, MY orcid.org/0000-0003-3131-9121, Davies, V et al. (20 more authors) (2022) Comprehensive genetic and functional analyses of Fc gamma receptors influence on response to rituximab therapy for autoimmunity. eBioMedicine, 86. 104343. ISSN 2352-3964

MR/T020504/1

Tanner, G., Barrow, R., Ajaib, S. et al. (27 more authors) (2024) IDHwt glioblastomas can be stratified by their transcriptional response to standard treatment, with implications for targeted therapy. Genome Biology, 25. 45. ISSN 1474-760X

Tanner, G., Finetti, M.A., Pollock, S. et al. (13 more authors) (2022) IDHwt Glioblastomas Show Opposing Resistance Mechanisms Across Patients in Response to Standard Treatment. In: BNOS 2022, 22-24 Jun 2022, Liverpool.

Varn, F.S., Johnson, K.C., Martinek, J. et al. (39 more authors) (2022) Longitudinal analysis of diffuse glioma reveals cell state dynamics at recurrence associated with changes in genetics and the microenvironment. In: American Association for Cancer Research Annual Meeting 2022, 08-13 Apr 2022, Philadelphia.

N/A

Thorne, JL orcid.org/0000-0002-3037-8528, Battaglia, S, Baxter, DE orcid.org/0000-0001-8830-6802 et al. (8 more authors) (2018) MiR-19b non-canonical binding is directed by HuR and confers chemosensitivity through regulation of P-glycoprotein in breast cancer. BBA - Gene Regulatory Mechanisms, 1861 (11). pp. 996-1006. ISSN 1874-9399

NCRN CC

Selby, P, Liu, L, Downing, A orcid.org/0000-0002-0335-7801 et al. (10 more authors) (2019) How can clinical research improve European health outcomes in cancer? Journal of Cancer Policy, 20. ARTN 100182. ISSN 2213-5383

Hall, PS, Swinson, D, Cairns, DA orcid.org/0000-0002-2338-0179 et al. (32 more authors) (2021) Efficacy of Reduced-Intensity Chemotherapy With Oxaliplatin and Capecitabine on Quality of Life and Cancer Control Among Older and Frail Patients With Advanced Gastroesophageal Cancer: The GO2 Phase 3 Randomized Clinical Trial. JAMA oncology, 7 (6). pp. 869-877. ISSN 2374-2437

Brown, LC, Graham, J, Fisher, D et al. (15 more authors) (2022) Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer. Clinical Trials, 19 (2). pp. 146-157. ISSN 1740-7745

Lee, RW, Danson, S, Elliot, M et al. (8 more authors) (2022) Importance of clinical research for the UK's 10-year cancer plan. The Lancet Oncology. ISSN 1470-2045

NCRN-EORTC-CR-UK LIASION

Lee, RW, Danson, S, Elliot, M et al. (8 more authors) (2022) Importance of clinical research for the UK's 10-year cancer plan. The Lancet Oncology. ISSN 1470-2045

NIHR 129268

Lee, RW, Danson, S, Elliot, M et al. (8 more authors) (2022) Importance of clinical research for the UK's 10-year cancer plan. The Lancet Oncology. ISSN 1470-2045

NIHR202395

Robinson, JI orcid.org/0000-0001-5425-7520, Md Yusof, MY orcid.org/0000-0003-3131-9121, Davies, V et al. (20 more authors) (2022) Comprehensive genetic and functional analyses of Fc gamma receptors influence on response to rituximab therapy for autoimmunity. eBioMedicine, 86. 104343. ISSN 2352-3964

NO EXT REF GIVEN

Ouboussad, L, Wong, C, Hunt, L et al. (3 more authors) (2016) A2.40 Investigating IL-6 pathway signalling kinetics in peripheral blood single cell subsets with tocilizumab therapy in patients with early rheumatoid arthritis. In: Annals of the Rheumatic Diseases. 36th European Workshop for Rheumatology Research, 25-27 Feb 2016, York, UK. BMJ Publishing Group , A31-A31.

NONE GIVEN

Ouboussad, L, Wong, C, Hunt, L et al. (3 more authors) (2016) A2.40 Investigating IL-6 pathway signalling kinetics in peripheral blood single cell subsets with tocilizumab therapy in patients with early rheumatoid arthritis. In: Annals of the Rheumatic Diseases. 36th European Workshop for Rheumatology Research, 25-27 Feb 2016, York, UK. BMJ Publishing Group , A31-A31.

Ouboussad, L, Wong, C, Hunt, L et al. (3 more authors) (2016) A2.40 Investigating IL-6 pathway signalling kinetics in peripheral blood single cell subsets with tocilizumab therapy in patients with early rheumatoid arthritis. In: Annals of the Rheumatic Diseases. 36th European Workshop for Rheumatology Research, 25-27 Feb 2016, York, UK. BMJ Publishing Group , A31-A31.

Ouboussad, L, Wong, C, Hunt, L et al. (3 more authors) (2016) A2.40 Investigating IL-6 pathway signalling kinetics in peripheral blood single cell subsets with tocilizumab therapy in patients with early rheumatoid arthritis. In: Annals of the Rheumatic Diseases. 36th European Workshop for Rheumatology Research, 25-27 Feb 2016, York, UK. BMJ Publishing Group , A31-A31.

NOT GIVEN

Hassanieh, S., Domingo, E., Blake, A. et al. (16 more authors) (2022) 337P Prediction of poor response to oxaliplatin by an RNA signature derived and validated in colorectal cancer clinical trials. In: Annals of Oncology. ESMO Congress 2022, 09-13 Sep 2022, Paris, France. Elsevier , S691.

Seligmann, JF, Domingo, E, Fisher, D et al. (17 more authors) (2022) The clinical relevance of tumor RAS/TP53 dual mutation in early and metastatic colorectal cancer (CRC). In: 2022 ASCO Annual Meeting, 03-07 Jun 2022, Chicago, Il, USA and Online.

Hoorn, ST, Sommeijer, DW, Elliot, F et al. (12 more authors) (2021) Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone. British Journal of Cancer. ISSN 0007-0920

Yin, J, Cohen, R, Jin, Z et al. (16 more authors) (2020) Prognostic and predictive impact of primary tumor sidedness in first-line trials for advanced colorectal cancer: An analysis of 7,828 patients in the ARCAD database. In: 2020 Gastrointestinal Cancers Symposium, 23-25 Jan 2020, San Francisco, California.

Yin, J, Cohen, R, Jin, Z et al. (16 more authors) (2020) Prognostic and predictive impact of primary tumor sidedness in first-line trials for advanced colorectal cancer: An analysis of 7,828 patients in the ARCAD database. In: 2020 Gastrointestinal Cancers Symposium, 23-25 Jan 2020, San Francisco, California.

Williams, C. orcid.org/0000-0002-1574-653X, Seligmann, J.F. orcid.org/0000-0003-4379-6005, Guetter, C. et al. (13 more authors) (2021) Artificial intelligence-assisted immunohistochemical (IHC) evaluation of tumor amphiregulin (AREG) and epiregulin (EREG) expression as a combined predictive biomarker for panitumumab (Pan) therapy benefit in RAS wild-type (wt) metastatic colorectal cancer (mCRC): Analysis within the phase III PICCOLO trial. In: Journal of Clinical Oncology. 2021 Gastrointestinal Cancers Symposium, 15-17 Jan 2021, Online. American Society of Clinical Oncology , p. 111.

Ouboussad, L, Wong, C, Hunt, L et al. (3 more authors) (2016) A2.40 Investigating IL-6 pathway signalling kinetics in peripheral blood single cell subsets with tocilizumab therapy in patients with early rheumatoid arthritis. In: Annals of the Rheumatic Diseases. 36th European Workshop for Rheumatology Research, 25-27 Feb 2016, York, UK. BMJ Publishing Group , A31-A31.

Brown, LC, Graham, J, Fisher, D et al. (15 more authors) (2022) Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer. Clinical Trials, 19 (2). pp. 146-157. ISSN 1740-7745

Newton Fund

Thorne, JL orcid.org/0000-0002-3037-8528, Battaglia, S, Baxter, DE orcid.org/0000-0001-8830-6802 et al. (8 more authors) (2018) MiR-19b non-canonical binding is directed by HuR and confers chemosensitivity through regulation of P-glycoprotein in breast cancer. BBA - Gene Regulatory Mechanisms, 1861 (11). pp. 996-1006. ISSN 1874-9399

No Ext Ref

Gracie, DJ orcid.org/0000-0001-9616-981X, Guthrie, EA orcid.org/0000-0002-5834-6616, Hamlin, PJ et al. (1 more author) (2018) Bi-directionality of Brain-Gut Interactions in Patients With Inflammatory Bowel Disease. Gastroenterology, 154 (6). pp. 1635-1646. ISSN 0016-5085

Hall, BJ, Hamlin, PJ, Gracie, DJ et al. (1 more author) (2018) The Effect of Antidepressants on the Course of Inflammatory Bowel Disease. Canadian Journal of Gastroenterology and Hepatology, 2018. ARTN 2047242. ISSN 2291-2789

Gracie, DJ orcid.org/0000-0001-9616-981X, Hamlin, PJ and Ford, AC orcid.org/0000-0001-6371-4359 (2018) Longitudinal impact of IBS-type symptoms on disease activity, healthcare utilization, psychological health, and quality of life in inflammatory bowel disease. American Journal of Gastroenterology, 113. pp. 702-712. ISSN 0002-9270

No Ext Ref Given

Rippaus, N, Taggart, D, Williams, J et al. (4 more authors) (2016) Metastatic site-specific polarization of macrophages in intracranial breast cancer metastases. Oncotarget, 7 (27). pp. 41473-41487.

Rippaus, N, Williams, J, Taggart, D et al. (3 more authors) (2016) Dural and parenchymal brain metastases in breast cancer are characterized by distinct inflammatory tumour microenvironments. In: Cancer Research. AACR Special Conference on Tumor Metastasis, 30 Nov - 03 Dec 2016, Austin, Texas, USA. American Association for Cancer Research .

Droop, A orcid.org/0000-0001-7695-7480, Bruns, A orcid.org/0000-0002-6970-4036, Tanner, G et al. (12 more authors) (2018) How to analyse the spatiotemporal tumour samples needed to investigate cancer evolution: A case study using paired primary and recurrent glioblastoma. International Journal of Cancer, 142 (8). pp. 1620-1626. ISSN 0020-7136

Barthel, F, Johnson, KC, Frederick Jr, V et al. (10 more authors) (2019) GENE-28. Longitudinal Molecular Trajectories of Diffuse Glioma in Adults. In: 24th Annual Scientific Meeting and Education Day of the Society for Neuro-Oncology, 20-24 Nov 2019, Phoenix, Arizona, USA.

Barthel, FP, Johnson, KC, Varn, FS et al. (86 more authors) (2019) Longitudinal Molecular Trajectories of Diffuse Glioma in Adults. Nature, 576. pp. 112-120. ISSN 0028-0836

Not Known

Rippaus, N, Taggart, D, Williams, J et al. (4 more authors) (2016) Metastatic site-specific polarization of macrophages in intracranial breast cancer metastases. Oncotarget, 7 (27). pp. 41473-41487.

Rippaus, N, Taggart, D, Williams, J et al. (4 more authors) (2016) Metastatic site-specific polarization of macrophages in intracranial breast cancer metastases. Oncotarget, 7 (27). pp. 41473-41487.

Rippaus, N, Williams, J, Taggart, D et al. (3 more authors) (2016) Dural and parenchymal brain metastases in breast cancer are characterized by distinct inflammatory tumour microenvironments. In: Cancer Research. AACR Special Conference on Tumor Metastasis, 30 Nov - 03 Dec 2016, Austin, Texas, USA. American Association for Cancer Research .

Rippaus, N, Williams, J, Taggart, D et al. (3 more authors) (2016) Dural and parenchymal brain metastases in breast cancer are characterized by distinct inflammatory tumour microenvironments. In: Cancer Research. AACR Special Conference on Tumor Metastasis, 30 Nov - 03 Dec 2016, Austin, Texas, USA. American Association for Cancer Research .

Damé-Teixeira, N, Parolo, CCF, Maltz, M et al. (3 more authors) (2016) Actinomyces spp. gene expression in root caries lesions. Journal of Oral Microbiology, 8. 32383. ISSN 2000-2297

Cowling, P, Hackney, R, Dube, B orcid.org/0000-0003-3277-3414 et al. (6 more authors) (2020) The use of a synthetic shoulder patch for large and massive rotator cuff tears – a feasibility study. BMC Musculoskeletal Disorders, 21 (1). 213. ISSN 1471-2474

Barthel, FP, Johnson, KC, Varn, FS et al. (86 more authors) (2019) Longitudinal Molecular Trajectories of Diffuse Glioma in Adults. Nature, 576. pp. 112-120. ISSN 0028-0836

Platt, JR, Todd, OM orcid.org/0000-0001-7212-8095, Hall, P et al. (14 more authors) (2023) FOxTROT2: innovative trial design to evaluate the role of neoadjuvant chemotherapy for treating locally advanced colon cancer in older adults or those with frailty. ESMO Open, 8 (1). 100642. ISSN 2059-7029

Rippaus, N, Manning, J, Droop, A et al. (9 more authors) (2019) OS9.5 Evidence that adult glioblastoma adapts to standard therapy though chromatin remodeling. In: 14th Meeting of the European Association of Neuro-Oncology, 19-22 Sep 2019, Lyon, France.

R&D PP 1107

Mathews, RJ, Robinson, JI orcid.org/0000-0001-5425-7520, Battellino, M et al. (17 more authors) (2014) Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment. Annals of the Rheumatic Diseases, 73 (6). pp. 1202-1210. ISSN 0003-4967

Ouboussad, L, Wong, C, Hunt, L et al. (3 more authors) (2016) A2.40 Investigating IL-6 pathway signalling kinetics in peripheral blood single cell subsets with tocilizumab therapy in patients with early rheumatoid arthritis. In: Annals of the Rheumatic Diseases. 36th European Workshop for Rheumatology Research, 25-27 Feb 2016, York, UK. BMJ Publishing Group , A31-A31.

R&D/PP/1101

Absolom, K orcid.org/0000-0002-5477-6643, Warrington, L orcid.org/0000-0002-8389-6134, Hudson, E orcid.org/0000-0001-8758-7163 et al. (17 more authors) (2021) Phase III Randomized Controlled Trial of eRAPID: eHealth Intervention During Chemotherapy. Journal of Clinical Oncology, 39 (7). pp. 734-747. ISSN 0732-183X

R&D/PP/1205

Derwa, Y, Williams, CJM, Sood, R et al. (6 more authors) (2018) Factors affecting clinical decision-making in inflammatory bowel disease and the role of point-of-care calprotectin. Therapeutic Advances in Gastroenterology, 11. pp. 1-18. ISSN 1756-283X

Gracie, DJ orcid.org/0000-0001-9616-981X, Williams, CJM, Sood, R orcid.org/0000-0003-1011-8910 et al. (4 more authors) (2017) Negative Effects on Psychological Health and Quality of Life of Genuine Irritable Bowel Syndrome-type Symptoms in Patients With Inflammatory Bowel Disease. Clinical Gastroenterology and Hepatology, 15 (3). 376-384.e5. ISSN 1542-3565

R&D/PP/1211

Damé-Teixeira, N, Parolo, CCF, Maltz, M et al. (3 more authors) (2016) Actinomyces spp. gene expression in root caries lesions. Journal of Oral Microbiology, 8. 32383. ISSN 2000-2297

Damé-Teixeira, N, Parolo, CCF, Maltz, M et al. (2 more authors) (2020) Gene expression profile of Scardovia spp. in the metatranscriptome of root caries. Brazilian Oral Research, 34. e042. ISSN 1806-8324

Ev, LD, Damé-Teixeira, N, Do, T orcid.org/0000-0002-5668-2181 et al. (2 more authors) (2020) The role of Candida albicans in root caries biofilms: an RNA-seq analysis. Journal of Applied Oral Science, 28. e20190578. ISSN 1678-7757

R116825

Robinson, JI orcid.org/0000-0001-5425-7520, Md Yusof, MY orcid.org/0000-0003-3131-9121, Davies, V et al. (20 more authors) (2022) Comprehensive genetic and functional analyses of Fc gamma receptors influence on response to rituximab therapy for autoimmunity. eBioMedicine, 86. 104343. ISSN 2352-3964

RCCCTF-Nov21\100001

Platt, JR, Todd, OM orcid.org/0000-0001-7212-8095, Hall, P et al. (14 more authors) (2023) FOxTROT2: innovative trial design to evaluate the role of neoadjuvant chemotherapy for treating locally advanced colon cancer in older adults or those with frailty. ESMO Open, 8 (1). 100642. ISSN 2059-7029

RCS REF 08-0843 SUBCONTR

Hassanieh, S., Domingo, E., Blake, A. et al. (16 more authors) (2022) 337P Prediction of poor response to oxaliplatin by an RNA signature derived and validated in colorectal cancer clinical trials. In: Annals of Oncology. ESMO Congress 2022, 09-13 Sep 2022, Paris, France. Elsevier , S691.

Seligmann, JF, Domingo, E, Fisher, D et al. (17 more authors) (2022) The clinical relevance of tumor RAS/TP53 dual mutation in early and metastatic colorectal cancer (CRC). In: 2022 ASCO Annual Meeting, 03-07 Jun 2022, Chicago, Il, USA and Online.

Platt, JR, Todd, OM orcid.org/0000-0001-7212-8095, Hall, P et al. (14 more authors) (2023) FOxTROT2: innovative trial design to evaluate the role of neoadjuvant chemotherapy for treating locally advanced colon cancer in older adults or those with frailty. ESMO Open, 8 (1). 100642. ISSN 2059-7029

RG/16/1/32092

Zakkaroff, C orcid.org/0000-0003-3668-8794, Biglands, JD orcid.org/0000-0002-1161-5022, Greenwood, JP orcid.org/0000-0002-2861-0914 et al. (4 more authors) (2018) Patient-specific coronary blood supply territories for quantitative perfusion analysis. Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization, 6 (2). pp. 137-154. ISSN 2168-1163

RP-DG-1209-10031

Absolom, K orcid.org/0000-0002-5477-6643, Warrington, L orcid.org/0000-0002-8389-6134, Hudson, E orcid.org/0000-0001-8758-7163 et al. (17 more authors) (2021) Phase III Randomized Controlled Trial of eRAPID: eHealth Intervention During Chemotherapy. Journal of Clinical Oncology, 39 (7). pp. 734-747. ISSN 0732-183X

RP-PG-0611-20008

Absolom, K orcid.org/0000-0002-5477-6643, Warrington, L orcid.org/0000-0002-8389-6134, Hudson, E orcid.org/0000-0001-8758-7163 et al. (17 more authors) (2021) Phase III Randomized Controlled Trial of eRAPID: eHealth Intervention During Chemotherapy. Journal of Clinical Oncology, 39 (7). pp. 734-747. ISSN 0732-183X

RSC91

Ouboussad, L, Wong, C, Hunt, L et al. (3 more authors) (2016) A2.40 Investigating IL-6 pathway signalling kinetics in peripheral blood single cell subsets with tocilizumab therapy in patients with early rheumatoid arthritis. In: Annals of the Rheumatic Diseases. 36th European Workshop for Rheumatology Research, 25-27 Feb 2016, York, UK. BMJ Publishing Group , A31-A31.

SENIOR INVESTIGATOR AWAR

Robinson, JI orcid.org/0000-0001-5425-7520, Md Yusof, MY orcid.org/0000-0003-3131-9121, Davies, V et al. (20 more authors) (2022) Comprehensive genetic and functional analyses of Fc gamma receptors influence on response to rituximab therapy for autoimmunity. eBioMedicine, 86. 104343. ISSN 2352-3964

SRC009

Ouboussad, L, Wong, C, Hunt, L et al. (3 more authors) (2016) A2.40 Investigating IL-6 pathway signalling kinetics in peripheral blood single cell subsets with tocilizumab therapy in patients with early rheumatoid arthritis. In: Annals of the Rheumatic Diseases. 36th European Workshop for Rheumatology Research, 25-27 Feb 2016, York, UK. BMJ Publishing Group , A31-A31.

TS/S012702/1 104687

Williams, C. orcid.org/0000-0002-1574-653X, Seligmann, J.F. orcid.org/0000-0003-4379-6005, Guetter, C. et al. (13 more authors) (2021) Artificial intelligence-assisted immunohistochemical (IHC) evaluation of tumor amphiregulin (AREG) and epiregulin (EREG) expression as a combined predictive biomarker for panitumumab (Pan) therapy benefit in RAS wild-type (wt) metastatic colorectal cancer (mCRC): Analysis within the phase III PICCOLO trial. In: Journal of Clinical Oncology. 2021 Gastrointestinal Cancers Symposium, 15-17 Jan 2021, Online. American Society of Clinical Oncology , p. 111.

X120

Hall, P, Swinson, D, Lord, S et al. (23 more authors) (2019) Optimizing Chemotherapy for Frail and Elderly Patients with Advanced Gastroesophageal Cancer (aGOAC): the GO2 Phase III Trial. In: 2019 NCRI Cancer Conference of National Cancer Research Institute, 03-05 Nov 2019, Glasgow, Scotland, UK.

Hall, PS, Swinson, D, Cairns, DA orcid.org/0000-0002-2338-0179 et al. (32 more authors) (2021) Efficacy of Reduced-Intensity Chemotherapy With Oxaliplatin and Capecitabine on Quality of Life and Cancer Control Among Older and Frail Patients With Advanced Gastroesophageal Cancer: The GO2 Phase 3 Randomized Clinical Trial. JAMA oncology, 7 (6). pp. 869-877. ISSN 2374-2437

Platt, JR, Todd, OM orcid.org/0000-0001-7212-8095, Hall, P et al. (14 more authors) (2023) FOxTROT2: innovative trial design to evaluate the role of neoadjuvant chemotherapy for treating locally advanced colon cancer in older adults or those with frailty. ESMO Open, 8 (1). 100642. ISSN 2059-7029

m16-4

Subramanian, V orcid.org/0000-0003-3603-0861, Burr, NE orcid.org/0000-0003-1988-2982 and Hull, MA orcid.org/0000-0001-7414-1576 (2018) Reply: Opioid Toxicity in Inflammatory Bowel Disease Patients Likely Includes Direct Enterocyte Effects That Exacerbate Disease. Clinical Gastroenterology and Hepatology, 16 (10). pp. 1680-1681. ISSN 1542-3565