Chemotherapy induces Notch1-dependent MRP1 up-regulation, inhibition of which sensitizes breast cancer cells to chemotherapy

Kim, B, Stephen, SL, Hanby, AM et al. (9 more authors) (2015) Chemotherapy induces Notch1-dependent MRP1 up-regulation, inhibition of which sensitizes breast cancer cells to chemotherapy. BMC Cancer, 15. 634. ISSN 1471-2407

Abstract

Metadata

Authors/Creators:
  • Kim, B
  • Stephen, SL
  • Hanby, AM
  • Horgan, K
  • Perry, SL
  • Richardson, J
  • Roundhill, EA
  • Valleley, EMA
  • Verghese, ET
  • Williams, BJ
  • Thorne, JL
  • Hughes, TA
Copyright, Publisher and Additional Information: © 2015, Kim et al. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Keywords: Notch; ABC transporters; Chemoresistance; Breast Cancer; MRP1; Chemotherapy
Dates:
  • Published: September 2015
  • Accepted: 24 August 2015
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Biological Sciences (Leeds)
The University of Leeds > Faculty of Maths and Physical Sciences (Leeds) > School of Food Science and Nutrition (Leeds)
The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Inst of Biomed & Clin Sciences (LIBACS) (Leeds) > Genetics (LIBACS) (Leeds)
The University of Leeds > Faculty of Medicine and Health (Leeds) > Institute of Molecular Medicine (LIMM) (Leeds) > Section of Molecular Gastroenterology (Leeds)
The University of Leeds > Faculty of Medicine and Health (Leeds) > Institute of Molecular Medicine (LIMM) (Leeds) > Section of Experimental Oncology (Leeds)
The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cancer and Pathology (LICAP) > Section of Experimental Oncology (Leeds)
Funding Information:
FunderGrant number
Yorkshire Cancer ResearchLPP064
Yorkshire Cancer ResearchLPP064
Depositing User: Symplectic Publications
Date Deposited: 25 Aug 2015 11:42
Last Modified: 22 Feb 2019 09:48
Published Version: http://dx.doi.org/10.1186/s12885-015-1625-y
Status: Published
Publisher: BioMed Central
Identification Number: https://doi.org/10.1186/s12885-015-1625-y

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