Small molecule binding sites on the Ras:SOS complex can be exploited for inhibition of Ras activation.

Winter, JJ, Anderson, M, Blades, K et al. (16 more authors) (2015) Small molecule binding sites on the Ras:SOS complex can be exploited for inhibition of Ras activation. Journal of Medicinal Chemistry, 58 (5). 2265 - 2274. ISSN 0022-2623

Abstract

Metadata

Authors/Creators:
  • Winter, JJ
  • Anderson, M
  • Blades, K
  • Brassington, C
  • Breeze, AL
  • Chresta, C
  • Embrey, K
  • Fairley, G
  • Faulder, P
  • Finlay, MR
  • Kettle, JG
  • Nowak, T
  • Overman, R
  • Patel, SJ
  • Perkins, P
  • Spadola, L
  • Tart, J
  • Tucker, JA
  • Wrigley, G
Copyright, Publisher and Additional Information: © 2015 American Chemical Society. This document is the Accepted Manuscript version of a Published Work that appeared in final form in Journal of Medicinal Chemistry, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/jm501660t
Dates:
  • Published: 26 February 2015
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Biological Sciences (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 14 Oct 2015 15:16
Last Modified: 04 Nov 2017 14:54
Published Version: http://dx.doi.org/10.1021/jm501660t
Status: Published
Publisher: American Chemical Society
Identification Number: https://doi.org/10.1021/jm501660t
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